Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Andrew R. Crow"'
Autor:
Danielle Marjoram, Alan H. Lazarus, Ian K. Campbell, Michael Kim, Patrick J. Mott, Jennifer Brasseit, Chao Ching Jen, Andrew R. Crow, Rick Kapur, Simrat S Kahlon, Adrian Zuercher, Yoelys Cruz-Leal, Sandra Koernig, Issaka Yougbaré, Fabian Käsermann, Ramsha Khan, Alaa Amash, Heyu Ni, John W. Semple
Publikováno v:
Science translational medicine, 11(506):eaau8217. American Association for the Advancement of Science
Treatment of autoimmune and inflammatory diseases typically involves immune suppression. In an opposite strategy, we show that administration of the highly inflammatory erythrocyte-specific antibody Ter119 into mice remodels the monocyte cellular lan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3775f874a82cc199d63ec89e8a03f0
https://pure.amc.nl/en/publications/treating-murine-inflammatory-diseases-with-an-antierythrocyte-antibody(07971f1e-2181-4261-89c4-21ccc0858001).html
https://pure.amc.nl/en/publications/treating-murine-inflammatory-diseases-with-an-antierythrocyte-antibody(07971f1e-2181-4261-89c4-21ccc0858001).html
Autor:
Andrew R. Crowley, Matthew R. Mehlenbacher, Mohammad M. Sajadi, Anthony L. DeVico, George K. Lewis, Margaret E. Ackerman
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTAntibody-mediated effector functions are widely considered to unfold according to an associative model of IgG-Fcγ receptor (FcγR) interactions. The associative model presupposes that Fc receptors cannot discriminate antigen-bound IgG from f
Externí odkaz:
https://doaj.org/article/5559437caf7c436bac7eade70d7f9afd
Publikováno v:
Transfusion. 55:1492-1500
Background Several monoclonal antibodies to CD44 can successfully ameliorate murine immune thrombocytopenia (ITP). As these antibodies may be a potential replacement for intravenous immune globulin (IVIG) in the treatment of ITP and other autoimmune
Autor:
Andrew R. Crow, Alan H. Lazarus
Publikováno v:
Seminars in Hematology. 53:S20-S22
Immune thrombocytopenia (ITP) is an autoimmune disorder characterised by platelet clearance resulting from the production of platelet-reactive autoantibodies. Platelet clearance appears to occur mainly via phagocytosis in the mononuclear phagocytic s
Publikováno v:
Journal of Thrombosis and Haemostasis. 7:245-248
Intravenous immunoglobulin (IVIg) is used to treat an ever-increasing number of autoimmune diseases. While the exact mechanism of action of IVIg has remained elusive, many theories have been suggested, including mononuclear phagocytic system blockade
Autor:
Vinayakumar Siragam, Andrew R. Crow, John Freedman, Alan H. Lazarus, Hoang Le-Tien, Davor Brinc
Publikováno v:
The Journal of Immunology. 181:948-953
Hemolytic disease of the fetus and newborn can be effectively prevented by administration of anti-D to the mother. The administered IgG results in the attenuation of RBC-specific Ab production, a process termed Ab-mediated immune suppression (AMIS).
Publikováno v:
ISBT Science Series. 3:152-158
Evidence for the Role of a Second Fc-Binding Receptor in Placental IgG Transfer in Nonhuman Primates
Autor:
Yvonne J. Rosenberg, Tracy Ordonez, Urjeet S. Khanwalkar, Philip Barnette, Shilpi Pandey, Iara M. Backes, Claire E. Otero, Benjamin S. Goldberg, Andrew R. Crowley, David A. Leib, Mariya B. Shapiro, Xiaoming Jiang, Lori A. Urban, Jonathan Lees, Ann J. Hessell, Sallie Permar, Nancy L. Haigwood, Margaret E. Ackerman
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Transplacental transfer of maternal antibodies provides the fetus and newborn with passive protection against infectious diseases. While the role of the highly conserved neonatal Fc receptor (FcRn) in transfer of IgG in mammals is undisputed
Externí odkaz:
https://doaj.org/article/25f9b49593274f65bc8c9255adb1a843
Publikováno v:
British Journal of Haematology. 139:275-279
Haemolytic disease of the newborn (HDN) can be prevented by the passive administration of anti-D to the mother. The most accepted theory to describe this activity of anti-D is based upon its ability to clear opsonized erythrocytes before their recogn
Publikováno v:
Acta Paediatrica. 87:21-25
Adult chronic idiopathic thrombocytopenic purpura (ITP) is an autoimmune disease characterized by production of autoreactive antibodies to platelet antigens. It is now becoming clear that autoantibody production, in general, is regulated by T helper