Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Andrew R. Collins"'
Autor:
Rosalie K. Elespuru, Shareen H. Doak, Andrew R. Collins, Maria Dusinska, Stefan Pfuhler, Mugimane Manjanatha, Renato Cardoso, Connie L. Chen
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Genotoxicity testing is performed to determine potential hazard of a chemical or agent for direct or indirect DNA interaction. Testing may be a surrogate for assessment of heritable genetic risk or carcinogenic risk. Testing of nanomaterials (NM) for
Externí odkaz:
https://doaj.org/article/2d21ba7877bd47e2a4f12d4d14fd3fcd
Autor:
Andrew R. Collins, Amaia Azqueta, Trine Gjesti Bentzen, Torgrim M. Langleite, Yolanda Lorenzo, Sergey Shaposhnikov
Publikováno v:
Bioingeniøren, Vol 45, Iss 5, Pp 6-11 (2010)
DNA damage is recognised as the first step in the process of carcinogenesis, induced by endogenous or environmental agents. At low levels, it is best detected with the comet assay (single cell gel electrophoresis), a method based on electrophoresis o
Externí odkaz:
https://doaj.org/article/48cd8c40e59d4ecc896447719db41e3e
Publikováno v:
Frontiers in Genetics, Vol 6 (2015)
Externí odkaz:
https://doaj.org/article/c9acc5bbb04d462d999b98117b9d835d
In vivo genotoxicity of nitramines, transformation products of amine-based carbon capture technology
Autor:
Claire Coutris, Andrew R. Collins
Publikováno v:
Frontiers in Genetics, Vol 6 (2015)
In times where we need to reduce our CO2 emissions to the atmosphere, it is important to get a clearer picture of the environmental impacts associated with potential mitigation technologies. Chemical absorption with amines is emerging as the most adv
Externí odkaz:
https://doaj.org/article/3b6a88d9bc624b9caa144e986edbd25c
Publikováno v:
Frontiers in Genetics, Vol 5 (2014)
Cellular repair enzymes remove virtually all DNA damage before it is fixed; repair therefore plays a crucial role in preventing cancer. Repair studied at the level of transcription correlates poorly with enzyme activity, and so assays of phenotype ar
Externí odkaz:
https://doaj.org/article/b026451dd4f04bd6b104633745a13cfe
Autor:
Pavel Vodicka, Alessio Naccarati, Pavel Soucek, Rajiv Kumar, Lubos Holubec, Vaclav Liska, Michaela Schneiderova, Miroslav Levy, Ludmila Lipska, Jiri Svec, Ludmila Vodickova, Pavel Prochazka, Andrew R. Collins, Vlasta Korenkova, Jana Slyskova
PDF file, 59K, Table shows list of genes analyzed by MSP with their respective primers sequences and reaction conditions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b33d2718e56a3a84111565549d4e7e37
https://doi.org/10.1158/1078-0432.22446977
https://doi.org/10.1158/1078-0432.22446977
Autor:
Pavel Vodicka, Alessio Naccarati, Pavel Soucek, Rajiv Kumar, Lubos Holubec, Vaclav Liska, Michaela Schneiderova, Miroslav Levy, Ludmila Lipska, Jiri Svec, Ludmila Vodickova, Pavel Prochazka, Andrew R. Collins, Vlasta Korenkova, Jana Slyskova
PDF file, 65K, Table shows list of genes analyzed by qPCR with their respective primers sequences and reaction conditions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c1049aad19fde6ea9470b0b23e3f031
https://doi.org/10.1158/1078-0432.22446980.v1
https://doi.org/10.1158/1078-0432.22446980.v1
Autor:
Pavel Vodicka, Alessio Naccarati, Pavel Soucek, Rajiv Kumar, Lubos Holubec, Vaclav Liska, Michaela Schneiderova, Miroslav Levy, Ludmila Lipska, Jiri Svec, Ludmila Vodickova, Pavel Prochazka, Andrew R. Collins, Vlasta Korenkova, Jana Slyskova
Purpose: DNA repair capacity (DRC) is a determinant not only of cancer development but also of individual response to therapy. Previously, altered base and nucleotide excision repair (BER and NER) have been described in lymphocytes of patients with s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3213a70bc6e3af2ee80e57890276dd19
https://doi.org/10.1158/1078-0432.c.6520937
https://doi.org/10.1158/1078-0432.c.6520937
Autor:
Pavel Vodicka, Alessio Naccarati, Pavel Soucek, Rajiv Kumar, Lubos Holubec, Vaclav Liska, Michaela Schneiderova, Miroslav Levy, Ludmila Lipska, Jiri Svec, Ludmila Vodickova, Pavel Prochazka, Andrew R. Collins, Vlasta Korenkova, Jana Slyskova
PDF file, 57K, Table shows list of genes analyzed by MS-HRM with their respective primers sequences and reaction conditions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba7b58ded3f0c6659e7ec583e9ac3ba
https://doi.org/10.1158/1078-0432.22446974
https://doi.org/10.1158/1078-0432.22446974
Autor:
Andrew R. Collins, Maria Dusinska
Publikováno v:
The Comet Assay in Toxicology ISBN: 9781782622871
This review will focus on biomarkers of genotoxic exposure and cancer risk, and in particular on the measurement of DNA damage and DNA repair using the Comet assay. Molecular biomarkers can be applied in the context of case-control, cohort or interve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::047b34c41beead7812952dc0a48bc0bc
https://doi.org/10.1039/9781782622895-00238
https://doi.org/10.1039/9781782622895-00238