Zobrazeno 1 - 4
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pro vyhledávání: '"Andrew R. Beardsley"'
Autor:
Daniel C. Flynn, Xinghui Sun, Jun Liu, Lyndell Millecchia, Vincent Castranova, Andrew R. Beardsley
Publikováno v:
Journal of Biological Chemistry. 282:7232-7241
When cells are migrating, caveolin-1, the principal protein component of caveolae, is excluded from the leading edge and polarized at the cell rear. The dynamic feature depends on a specific sequence motif that directs intracellular trafficking of th
Publikováno v:
FEBS letters. 583(22)
Caveolin-1 (Cav-1) plays an important role in the organization of signaling molecules involved in a variety of signaling pathways, including those mediating cell motility. Here we show that amino acids K47–K57 of Cav-1 are a highly conserved sequen
Publikováno v:
Cell cycle (Georgetown, Tex.). 6(2)
Angiogenesis, the development of new blood vessels from preexisting capillary, is required for tumor growth and metastasis. The process is not fully understood yet, but involves endothelial cell proliferation, migration and differentiation. Recently,
Publikováno v:
The Journal of biological chemistry. 280(5)
The ability of a cell to move requires the asymmetrical organization of cellular activities. To investigate polarized cellular activity in moving endothelial cells, human endothelial cells were incubated in a Dunn chamber to allow migration toward va