Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Andrew R Rahmberg"'
Autor:
Zachary Strongin, Timothy N Hoang, Gregory K Tharp, Andrew R Rahmberg, Justin L Harper, Kevin Nguyen, Lavinia Franchitti, Barbara Cervasi, Max Lee, Zhan Zhang, Eli A Boritz, Guido Silvestri, Vincent C Marconi, Steven E Bosinger, Jason M Brenchley, Deanna A Kulpa, Mirko Paiardini
Publikováno v:
PLoS Pathogens, Vol 18, Iss 7, p e1010723 (2022)
Despite the advent of effective antiretroviral therapy (ART), human immunodeficiency virus (HIV) continues to pose major challenges, with extensive pathogenesis during acute and chronic infection prior to ART initiation and continued persistence in a
Externí odkaz:
https://doaj.org/article/0d173f19d60843dc8264274e0962880c
Autor:
James R. Rose, Bagdeser Akdogan-Ozdilek, Andrew R. Rahmberg, Michael D. Powell, Sakeenah L. Hicks, Christopher D. Scharer, Jeremy M. Boss
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-19 (2023)
An integrated analysis uncovers transcriptional and epigenetic differences of human circulating memory T cell subsets and identifies unique transcription factor networks associated with memory subset differentiation.
Externí odkaz:
https://doaj.org/article/a067bd43035a480cbc06a1f70910044e
Autor:
Quentin Le Hingrat, Paola Sette, Cuiling Xu, Andrew R. Rahmberg, Lilas Tarnus, Haritha Annapureddy, Adam Kleinman, Egidio Brocca-Cofano, Ranjit Sivanandham, Sindhuja Sivanandham, Tianyu He, Daniel J. Capreri, Dongzhu Ma, Jacob D. Estes, Jason M. Brenchley, Cristian Apetrei, Ivona Pandrea
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
HIV infection results in the depletion of CD4+ T cells overtime and the loss of coordinated cellular immunity, but how this corresponds to the SIV infected African Green Monkey (AGM) model of non-progressive disease is not known. Here the authors ass
Externí odkaz:
https://doaj.org/article/3fb3a179a4c24353b99b12d1f312421c
Autor:
Alexandra M. Ortiz, Jennifer Simpson, Charlotte A. Langner, Phillip J. Baker, Cynthia Aguilar, Kelsie Brooks, Jacob K. Flynn, Carol L. Vinton, Andrew R. Rahmberg, Heather D. Hickman, Jason M. Brenchley
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Defective gastrointestinal barrier function and, in turn, microbial translocation have been identified as significant contributors to persistent inflammation in antiretroviral (ARV)-treated people living with HIV. Metabolic supplementation o
Externí odkaz:
https://doaj.org/article/cf5b60b70f2f47a591ba68af57beaeed
Autor:
Andrew R. Rahmberg, Chuanfeng Wu, Taehoon Shin, So Gun Hong, Luxin Pei, Heather D. Hickman, Cynthia E. Dunbar, Jason M. Brenchley
Publikováno v:
Blood. 140:38-39
Macrophages are critical orchestrators of tissue immunity, from the initiation and resolution of antimicrobial immune responses to the subsequent repair of damaged tissue. Murine studies have demonstrated that tissue-resident macrophages are comprise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c34cc533775453ee957d349cba6681e
https://doi.org/10.1182/blood-2022-158576
https://doi.org/10.1182/blood-2022-158576
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 209(2)
African green monkeys (AGMs), Chlorocebus pygerythrus, are a natural host for a lentivirus related to HIV, SIV. SIV-infected AGMs rarely progress to AIDS despite robust viral replication. Though multiple mechanisms are involved, a primary component i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36af70942f1ac4ca447f557cc4a2065d
https://pubmed.ncbi.nlm.nih.gov/35750337
https://pubmed.ncbi.nlm.nih.gov/35750337
Autor:
Alexandra M, Ortiz, Jennifer, Simpson, Charlotte A, Langner, Phillip J, Baker, Cynthia, Aguilar, Kelsie, Brooks, Jacob K, Flynn, Carol L, Vinton, Andrew R, Rahmberg, Heather D, Hickman, Jason M, Brenchley
Publikováno v:
Scientific reports. 12(1)
Defective gastrointestinal barrier function and, in turn, microbial translocation have been identified as significant contributors to persistent inflammation in antiretroviral (ARV)-treated people living with HIV. Metabolic supplementation of short-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::84aa1c9024d4239d4e761290e213093c
https://pubmed.ncbi.nlm.nih.gov/35523797
https://pubmed.ncbi.nlm.nih.gov/35523797
Publikováno v:
The Journal of Immunology. 208:57.02-57.02
Memory T cells (MTC), an indispensable part of adaptive immune memory, have historically been categorized by the cell surface proteins CCR7 and CD45RA into specialized subtypes (TCM, TEM, and TEMRA), each with unique functions. However, the epigeneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::892654af9b6b9a082f49af0a889820e8
https://doi.org/10.4049/jimmunol.208.supp.57.02
https://doi.org/10.4049/jimmunol.208.supp.57.02
Autor:
Michael Duane Powell, James R Rose, Dennis Neeld, Andrew R Rahmberg, Christopher D Scharer, Jeremy M Boss
Publikováno v:
The Journal of Immunology. 208:112.21-112.21
The surface immune checkpoint inhibitor Programed Death-1 (PD-1), encoded by PDCD1, is expressed throughout the immune system. Notably, PD-1 expression is amongst its highest in a specialized subset of CD4+ T follicular helper (TFH) cells. TFH cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ac96d1a1a583a4634b20ba9d5682702
https://doi.org/10.4049/jimmunol.208.supp.112.21
https://doi.org/10.4049/jimmunol.208.supp.112.21
Autor:
Andrew R. Rahmberg, Jeremy M. Boss, Christopher D. Scharer, Parimal Majumder, Joshua T. Lee, Tian Mi, Gaurav Kumar
Publikováno v:
The Journal of Experimental Medicine
A super enhancer termed DR/DQ-SE within the MHC-II locus was examined by CRISPR mutagenesis. DR/DQ-SE was found to regulate HLA-DRB1, -DQA1, and -DQB1 gene expression by controlling chromatin interactions/looping between MHC-II gene promoters and CTC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f97c2a33b4dc49cf370550f79721167
http://europepmc.org/articles/PMC7041702
http://europepmc.org/articles/PMC7041702