Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Andrew R Pachner"'
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0160071 (2016)
Disease in the spinal cord is a major component of disability in multiple sclerosis, yet current techniques of imaging spinal cord injury are insensitive and nonspecific. This study seeks to remove this major impediment to research in multiple sclero
Externí odkaz:
https://doaj.org/article/539775f338f64d22a3e7c8071449bec2
Publikováno v:
Fluids and Barriers of the CNS, Vol 18, Iss 1, Pp 1-4 (2021)
Abstract Pilz et al. (Fluids Barriers CNS 17:7; 2020) investigated how CSF CXCL13 concentrations are influenced by CXCL13 serum concentrations and blood-CSF barrier (BCSFB) function, comparing the impact of serum CXCL13 levels and Qalbumin (CSF album
Externí odkaz:
https://doaj.org/article/9194d1a5cf214560aebc032a69ee1e45
Autor:
Andrew R. Pachner
Publikováno v:
Frontiers in Neurology, Vol 12 (2022)
There have been tremendous advances in the neuroimmunology of multiple sclerosis over the past five decades, which have led to improved diagnosis and therapy in the clinic. However, further advances must take into account an understanding of some of
Externí odkaz:
https://doaj.org/article/4bd540a6eef544f1adb559aec7a0b1f5
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Multiple Sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system. Once thought to be primarily driven by T cells, B cells are emerging as central players in MS immunopathogenesis. Interest in multiple B cell phenotypes i
Externí odkaz:
https://doaj.org/article/9e9cf9c7f9d042b18df4060c50d31ea3
Autor:
Adriana Marques, Henry M. Feder, Ira Schwartz, Gary P. Wormser, Andrew R. Pachner, Charles S. Pavia
Publikováno v:
Clin Infect Dis
The role that microorganisms might have in the development of Alzheimer disease is a topic of considerable interest. In this article, we discuss whether there is credible evidence that Lyme disease is a cause of Alzheimer disease and critically revie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79183192e7880c81c8266c183ff47a1c
https://doi.org/10.1093/cid/ciab993
https://doi.org/10.1093/cid/ciab993
Autor:
Yike Jiang, Chaya D. Patel, Richard Manivanh, Brian North, Iara M. Backes, David A. Posner, Francesca Gilli, Andrew R. Pachner, Lananh N. Nguyen, David A. Leib
Publikováno v:
mBio, Vol 8, Iss 4 (2017)
ABSTRACT While antibody responses to neurovirulent pathogens are critical for clearance, the extent to which antibodies access the nervous system to ameliorate infection is poorly understood. In this study on herpes simplex virus 1 (HSV-1), we demons
Externí odkaz:
https://doaj.org/article/6dbbb3e5cd3f47c88be594817ba86771
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-15 (2019)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background The mechanisms driving multiple sclerosis (MS), the most common cause of non-traumatic disability in young adults, remain unknown despite extensive research. Especially puzzling are the underlying molecular processes behind the two major d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab135102c4e8c4a73fd47ca156cd2cf3
http://link.springer.com/article/10.1186/s12974-019-1501-9
http://link.springer.com/article/10.1186/s12974-019-1501-9
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Multiple Sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system. Once thought to be primarily driven by T cells, B cells are emerging as central players in MS immunopathogenesis. Interest in multiple B cell phenotypes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5f78b8d3f9ac55fd65276572133fee
https://doi.org/10.3389/fimmu.2021.676686
https://doi.org/10.3389/fimmu.2021.676686
Publikováno v:
Fluids and Barriers of the CNS
Fluids and Barriers of the CNS, Vol 18, Iss 1, Pp 1-4 (2021)
Fluids and Barriers of the CNS, Vol 18, Iss 1, Pp 1-4 (2021)
Elevation of the chemokine CXCL13 in CSF frequently occurs during active and acute CNS inflammatory processes and presumably is associated with B cell-related immune activation. Elevation levels, however, vary a lot and "leaking" of CXCL13 from blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b457f63ab2593fe2ce6baaa2688801b
http://europepmc.org/articles/PMC7905854
http://europepmc.org/articles/PMC7905854
Publikováno v:
Multiple Sclerosis Journal-Experimental, Translational and Clinical
Background Clinicians caring for patients with Multiple Sclerosis (MS) need improved biomarkers to aid them in disease management. Objective We assessed the predictive value of the candidate biomarker CXCL13 index in comparison to oligoclonal bands (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b61f589f73e03641e3ff6aafc7fa5a4f
https://pubmed.ncbi.nlm.nih.gov/33403120
https://pubmed.ncbi.nlm.nih.gov/33403120