Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Andrew R McNamara"'
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131497 (2015)
The p53 tumor suppressor gene (TP53) is reported to be mutated in nearly half of all tumors and plays a central role in genome integrity. Detection of mutations in p53 can be accomplished by many assays, including the AmpliChip p53 Research Test. The
Externí odkaz:
https://doaj.org/article/0a256f9472b34d50842222be7dddf4af
Publikováno v:
Journal of Orthopaedic Trauma. 36:S1-S6
Objectives Performing an examination under general anesthesia (EUA) using dynamic stress fluoroscopy of patients with posterior wall acetabular fractures has been used as a tool to determine hip stability and the need for surgical intervention. The p
Publikováno v:
American journal of orthopedics (Belle Mead, N.J.). 45(3)
Friction blisters are a common sequela of many athletic activities. Their significance can range from minor annoyance to major performance disruptions. The latter is particularly true in baseball pitchers, who sustain repeated trauma between the base
Autor:
Andrew R. McNamara, Julio C. Sokolich, Timothy D. Light, Kokou D. Zamba, David K. Meyerholz, Amin D. Jaskille, Michelle Griffin
Publikováno v:
Journal of Surgical Research. 162:258-263
Background The cellular processes that contribute to cell death in burns are poorly understood. This study evaluated the distribution and extent of apoptosis in an established rat model of acute dermal burn injury. Materials and Methods A branding ir
Autor:
Kokou D. Zamba, Travis L. Piester, Timothy D. Light, Andrew R. McNamara, David K. Meyerholz, Amin D. Jaskille, Kristine C. Orion, Julio C. Sokolich
Publikováno v:
Journal of Trauma: Injury, Infection & Critical Care. 67:996-1003
Hypothesis: The addition of drotrecogin alfa (DA), an anti-inflammatory useful in septic shock, to standard burn shock resuscitation fluids will protect burned, injured skin from further injury. Methods: Anesthetized animals were subjected to a stand
Autor:
Andrew R. McNamara
Publikováno v:
AMA journal of ethics. 17(7)
The current state of our health care system is analogous to the status of science that Kuhn describes as "a proliferation of compelling articulations, the willingness to try anything, the expression of explicit discontent, the recourse to philosophy
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 6, p e0131497 (2015)
PLoS ONE, Vol 10, Iss 6, p e0131497 (2015)
The p53 tumor suppressor gene (TP53) is reported to be mutated in nearly half of all tumors and plays a central role in genome integrity. Detection of mutations in p53 can be accomplished by many assays, including the AmpliChip p53 Research Test. The
Autor:
Lutz-Peter Berg, Casey C. Case, Mark Isalan, Michael J. Moore, Albert Lai, Dmitry Guschin, H. Steven Zhang, Ya-Li Lee, Chris Ullman, Hong Qi, Albert R. Davalos, Bradley Campos, Andrew W. Snowden, Andrew R. McNamara, Siyuan Tan, Carl O. Pabo, Yann Jouvenot, S. Kaye Spratt, Philip D. Gregory, Lindsey Reynolds, Judith Campisi, Katherine Howes
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 100(21)
Zinc-finger protein transcription factors (ZFP TFs) can be designed to control the expression of any desired target gene, and thus provide potential therapeutic tools for the study and treatment of disease. Here we report that a ZFP TF can repress ta
Publikováno v:
Nucleic acids research. 30(17)
DNA methylation is now seen as a primary signal in the cell for mediating transcriptional repression through chromatin formation. The construction and evaluation of enzymes capable of influencing this process in vivo is therefore of significant inter
Autor:
Kevin G. Ford, Andrew R. McNamara
A three zinc-finger protein that binds specifically to the cDNA representing the unique fusion gene BCR:Abl, associated with acute lymphoblastic leukaemia, has previously been characterised. At this breakpoint, a sequence homology of 8/9 bp exists be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce4963097566ff677b91798f0385caa
https://europepmc.org/articles/PMC115248/
https://europepmc.org/articles/PMC115248/