Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Andrew R M Bradbury"'
Autor:
Nileena Velappan, Fortunato Ferrara, Sara D'Angelo, Devin Close, Leslie Naranjo, Madeline R Bolding, Sarah C Mozden, Camille B Troup, Donna K McCullough, Analyssa Gomez, Marijo Kedge, Andrew R M Bradbury
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0280930 (2023)
Antibodies are important reagents for research, diagnostics, and therapeutics. Many examples of chimeric proteins combining the specific target recognition of antibodies with complementing functionalities such as fluorescence, toxicity or enzymatic a
Externí odkaz:
https://doaj.org/article/11a2f16525564b46ab218f4b5b96ed0c
Autor:
M Lisa Phipps, Antoinetta M Lillo, Yulin Shou, Emily N Schmidt, Chad D Paavola, Leslie Naranjo, Sara Bemdich, Basil I Swanson, Andrew R M Bradbury, Jennifer S Martinez
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0160940 (2016)
Peptides are important affinity ligands for microscopy, biosensing, and targeted delivery. However, because they can have low affinity for their targets, their selection from large naïve libraries can be challenging. When selecting peptidic ligands
Externí odkaz:
https://doaj.org/article/a14a429d1cf94888b031aa2aef531c09
Autor:
Fortunato Ferrara, Adeline Fanni, Andre A. R. Teixeira, Esteban Molina, Camila Leal-Lopes, Ashley DeAguero, Sara D’Angelo, M. Frank Erasmus, Laura Spector, Luis Antonio Rodriguez Carnero, Jianquan Li, Thomas J. Pohl, Nikolai Suslov, Klervi Desrumeaux, Conor McMahon, Sagar Kathuria, Andrew R. M. Bradbury
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
We previously described an in vitro single-chain fragment (scFv) library platform originally designed to generate antibodies with excellent developability properties. The platform design was based on the use of clinical antibodies as scaffolds into w
Externí odkaz:
https://doaj.org/article/08adf8bbba7940a8b4cc3c5378c32316
Autor:
Fortunato Ferrara, Leslie A Naranjo, Sandeep Kumar, Tiziano Gaiotto, Harshini Mukundan, Basil Swanson, Andrew R M Bradbury
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49535 (2012)
BACKGROUND: Current diagnostic methods for tuberculosis (TB), a major global health challenge that kills nearly two million people annually, are time-consuming and inadequate. During infection a number of bacterial molecules that play a role in the i
Externí odkaz:
https://doaj.org/article/22b93ca1f51d4fa48c03a6110d02f1d6
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25727 (2011)
Antibody fragments are easily isolated from in vitro selection systems, such as phage and yeast display. Lacking the Fc portion of the antibody, they are usually labeled using small peptide tags recognized by antibodies. In this paper we present an e
Externí odkaz:
https://doaj.org/article/0c042e9ff1714f0ebaefad9539444eb6
Autor:
Antonietta M Lillo, Joanne E Ayriss, Yulin Shou, Steven W Graves, Andrew R M Bradbury, Peter Pavlik
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e27756 (2011)
BACKGROUND: Most Yersinia pestis strains are known to express a capsule-like antigen, fraction 1 (F1)(.) F1 is encoded by the caf1 gene located on the large 100-kb pFra plasmid, which is found in Y. pestis but not in closely related species such as Y
Externí odkaz:
https://doaj.org/article/f491a553c8f242ee98433e9ed026e874
Autor:
M. Frank Erasmus, Fortunato Ferrara, Sara D’Angelo, Laura Spector, Camila Leal-Lopes, André A. Teixeira, Jesper Sørensen, Suhani Nagpal, Kathryn Perea-Schmittle, Alok Choudhary, William Honnen, David Calianese, Luis Antonio Rodriguez Carnero, Simon Cocklin, Victor Greiff, Abraham Pinter, Andrew R. M. Bradbury
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/341f118a08db4ff7bb9c491729af0860
Autor:
M. Frank Erasmus, Molly Dovner, Fortunato Ferrara, Sara D’Angelo, André A. Teixeira, Camila Leal-Lopes, Laura Spector, Elizabeth Hopkins, Andrew R. M. Bradbury
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTAccurate and efficient affinity measurement techniques are essential for the biophysical characterization of therapeutic monoclonal antibodies, one of the fastest growing drug classes. Surface plasmon resonance (SPR) is widely used for determ
Externí odkaz:
https://doaj.org/article/8d9d6973ecb14fbf9cc087829f04f11c
Autor:
M. Frank Erasmus, Fortunato Ferrara, Sara D’Angelo, Laura Spector, Camila Leal‑Lopes, André A. Teixeira, Jesper Sørensen, Suhani Nagpal, Kathryn Perea‑Schmittle, Alok Choudhary, William Honnen, David Calianese, Luis Antonio Rodriguez Carnero, Simon Cocklin, Victor Greiff, Abraham Pinter, Andrew R. M. Bradbury
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/857d7a448bd248a0ae37d45019f7079d
Autor:
Fortunato Ferrara, Sara D’Angelo, M. Frank Erasmus, André A. Teixeira, Camila Leal-Lopes, Laura P. Spector, Tom Pohl, Adeline Fanni, Simon Cocklin, Andrew R. M. Bradbury
Publikováno v:
mAbs. 14
The intense international focus on the COVID-19 pandemic has provided a unique opportunity to use a wide array of novel tools to carry out scientific studies on the SARS-CoV-2 virus. The value of these comparative studies extends far beyond their con