Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Andrew R Lynch"'
Autor:
Amber S Zhou, John B Tucker, Christina M Scribano, Andrew R Lynch, Caleb L Carlsen, Sophia T Pop-Vicas, Srishrika M Pattaswamy, Mark E Burkard, Beth A Weaver
Publikováno v:
PLoS Biology, Vol 21, Iss 10, p e3002339 (2023)
Microtubule-targeted agents are commonly used for cancer treatment, though many patients do not benefit. Microtubule-targeted drugs were assumed to elicit anticancer activity via mitotic arrest because they cause cell death following mitotic arrest i
Externí odkaz:
https://doaj.org/article/45f914589aa54be58c9b45687e9358a8
Publikováno v:
eLife, Vol 11 (2022)
Chromosomal instability (CIN)—persistent chromosome gain or loss through abnormal mitotic segregation—is a hallmark of cancer that drives aneuploidy. Intrinsic chromosome mis-segregation rate, a measure of CIN, can inform prognosis and is a promi
Externí odkaz:
https://doaj.org/article/7f548a7a7f9c4dcaa81c622dfb9ba2ff
