Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Andrew R Hall"'
Autor:
Emmanuel Ansong, Qi Ying, Dede N Ekoue, Ryan Deaton, Andrew R Hall, Andre Kajdacsy-Balla, Wancai Yang, Peter H Gann, Alan M Diamond
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127295 (2015)
Selenium-Binding Protein 1 (SBP1, SELENBP1, hSP56) is a selenium-associated protein shown to be at lower levels in tumors, and its lower levels are frequently predictive of a poor clinical outcome. Distinguishing indolent from aggressive prostate can
Externí odkaz:
https://doaj.org/article/491d50acecea4c8b977a7c7e5b910602
Autor:
Hilary K Siddall, Derek M Yellon, Sang-Bing Ong, Uma A Mukherjee, Niall Burke, Andrew R Hall, Plamena R Angelova, Marthe H R Ludtmann, Emma Deas, Sean M Davidson, Mihaela M Mocanu, Derek J Hausenloy
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62400 (2013)
Mutations in PTEN inducible kinase-1 (PINK1) induce mitochondrial dysfunction in dopaminergic neurons resulting in an inherited form of Parkinson's disease. Although PINK1 is present in the heart its exact role there is unclear. We hypothesized that
Externí odkaz:
https://doaj.org/article/dde8266e1e2f4f309d4fe3816f92898f
Autor:
Tara J. Bowen, Andrew D. Southam, Andrew R. Hall, Ralf J. M. Weber, Gavin R. Lloyd, Ruth Macdonald, Amanda Wilson, Amy Pointon, Mark R. Viant
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Untargeted metabolomics is an established approach in toxicology for characterising endogenous metabolic responses to xenobiotic exposure. Detecting the xenobiotic and its biotransformation products as part of the metabolomics analysis provi
Externí odkaz:
https://doaj.org/article/4910e9a54ea449d1b77c4b11d29fc8ec
Autor:
Xiu-Yi Kwek, Andrew R. Hall, Wei-Wen Lim, Khairunnisa Katwadi, Poh Loong Soong, Elina Grishina, Kun-Han Lin, Gustavo Crespo-Avilan, En Ping Yap, Nur Izzah Ismail, Kroekkiat Chinda, Ying Ying Chung, Heming Wei, Winston Shim, David Montaigne, Andrew Tinker, Sang-Bing Ong, Derek J. Hausenloy
Publikováno v:
Scientific Reports. 12
Mitochondrial dysfunction induced by acute cardiac ischemia–reperfusion (IR), may increase susceptibility to arrhythmias by perturbing energetics, oxidative stress production and calcium homeostasis. Although changes in mitochondrial morphology are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d47b9eedc9ba586d15ea13dca89baa9a
https://doi.org/10.1038/s41598-022-25625-0
https://doi.org/10.1038/s41598-022-25625-0
Autor:
Andrew R. Hall, Qutuba G. Karwi, Sanjeev Kumar, Rachel Dongworth, Dunja Aksentijević, Tariq R. Altamimi, Kevin Timothy Fridianto, Kroekkiat Chinda, Sauri Hernandez-Resendiz, Mohammad U. Mahmood, Evangelos Michelakis, Chrishan J. Ramachandra, Jianhong Ching, Jose M. Vicencio, Michael J. Shattock, Jean-Paul Kovalik, Derek M. Yellon, Gary Lopaschuk, Derek J. Hausenloy
Publikováno v:
Scientific Reports. 12
Fasting increases susceptibility to acute myocardial ischaemia/reperfusion injury (IRI) but the mechanisms are unknown. Here, we investigate the role of the mitochondrial NAD+-dependent deacetylase, Sirtuin-3 (SIRT3), which has been shown to influenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::630b210e57f99b8be56b2c480b4892a4
https://doi.org/10.1038/s41598-022-23847-w
https://doi.org/10.1038/s41598-022-23847-w
Autor:
Giacomo Germani, Amar P. Dhillon, Emmanuel Tsochatzis, Margarita Papatheodoridi, Massimo Pinzani, Gary Burgess, Jeremy D. Gale, G. Pieri, Andrew R. Hall, Manuel Rodríguez-Perálvarez
Publikováno v:
Liver International. 41:1608-1613
Collagen proportionate area (CPA, %) is used to quantify liver fibrosis. Here, we assessed CPA performance to sub-classify cirrhosis. CPA was measured in explanted livers from consecutively transplanted patients for hepatitis C virus-related cirrhosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0006108d00126c1d8dcb2b9392df8fc
https://doi.org/10.1111/liv.14909
https://doi.org/10.1111/liv.14909
Autor:
Anja V. Gruszczyk, Alva M. Casey, Andrew M. James, Hiran A. Prag, Nils Burger, Georgina R. Bates, Andrew R. Hall, Fay M. Allen, Thomas Krieg, Kourosh Saeb-Parsy, Michael P. Murphy
Publikováno v:
Redox biology. 54
Funder: National Institute for Health Research (NIHR)
Cell models of cardiac ischemia-reperfusion (IR) injury are essential to facilitate understanding, but current monolayer cell models poorly replicate the in vivo IR injury that occurs within
Cell models of cardiac ischemia-reperfusion (IR) injury are essential to facilitate understanding, but current monolayer cell models poorly replicate the in vivo IR injury that occurs within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e66fd2d96bbee5510ebb4acd67eb7c4
https://pubmed.ncbi.nlm.nih.gov/35749842
https://pubmed.ncbi.nlm.nih.gov/35749842
Correction: Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction
Autor:
Jose Miguel Vicencio, Derek J. Hausenloy, Andrew R. Hall, Derek M. Yellon, RK Dongworth, Siavash Beikoghli Kalkhoran, Gerald W. Dorn, Alex Dyson, Niall Burke
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-1 (2021)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb84da09497a400294240f6c59baf2c
https://doi.org/10.1038/s41419-021-03946-8
https://doi.org/10.1038/s41419-021-03946-8
Publikováno v:
Trends in pharmacological sciences. 42(8)
Cardiac physiology and homeostasis are maintained by the interaction of multiple cell types, via both intra- and intercellular signaling pathways. Perturbations in these signaling pathways induced by oncology therapies can reduce cardiac function, ul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6fc4fd1564099131229e2a9ffd2b7b
https://pubmed.ncbi.nlm.nih.gov/34092416
https://pubmed.ncbi.nlm.nih.gov/34092416
Autor:
Thomas Krieg, Naveenan Navaratnam, Thomas P. Bright, Robin Willows, Michael P. Murphy, David Carling, Andrew R. Hall, Elizabeth C. Hinchy, Anja V. Gruszczyk, Georgina Bates
Publikováno v:
The Journal of Biological Chemistry
Mitochondrial reactive oxygen species (ROS) production is a tightly regulated redox signal that transmits information from the organelle to the cell. Other mitochondrial signals, such as ATP, are sensed by enzymes, including the key metabolic sensor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdaa64697d93b99a467072ee7b38115b
https://doi.org/10.1074/jbc.ra118.002579
https://doi.org/10.1074/jbc.ra118.002579