Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Andrew R Crow"'
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71882 (2013)
Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder characterized by a low platelet count and the production of anti-platelet antibodies. The majority of ITP patients have antibodies to platelet integrin α(IIb)β₃ (GPIIbIIIa) which ca
Externí odkaz:
https://doaj.org/article/65027d08a6b143549c4606c6147756a4
Autor:
Danielle Marjoram, Alan H. Lazarus, Ian K. Campbell, Michael Kim, Patrick J. Mott, Jennifer Brasseit, Chao Ching Jen, Andrew R. Crow, Rick Kapur, Simrat S Kahlon, Adrian Zuercher, Yoelys Cruz-Leal, Sandra Koernig, Issaka Yougbaré, Fabian Käsermann, Ramsha Khan, Alaa Amash, Heyu Ni, John W. Semple
Publikováno v:
Science translational medicine, 11(506):eaau8217. American Association for the Advancement of Science
Treatment of autoimmune and inflammatory diseases typically involves immune suppression. In an opposite strategy, we show that administration of the highly inflammatory erythrocyte-specific antibody Ter119 into mice remodels the monocyte cellular lan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3775f874a82cc199d63ec89e8a03f0
https://pure.amc.nl/en/publications/treating-murine-inflammatory-diseases-with-an-antierythrocyte-antibody(07971f1e-2181-4261-89c4-21ccc0858001).html
https://pure.amc.nl/en/publications/treating-murine-inflammatory-diseases-with-an-antierythrocyte-antibody(07971f1e-2181-4261-89c4-21ccc0858001).html
Publikováno v:
Transfusion. 55:1492-1500
Background Several monoclonal antibodies to CD44 can successfully ameliorate murine immune thrombocytopenia (ITP). As these antibodies may be a potential replacement for intravenous immune globulin (IVIG) in the treatment of ITP and other autoimmune
Autor:
Andrew R. Crow, Alan H. Lazarus
Publikováno v:
Seminars in Hematology. 53:S20-S22
Immune thrombocytopenia (ITP) is an autoimmune disorder characterised by platelet clearance resulting from the production of platelet-reactive autoantibodies. Platelet clearance appears to occur mainly via phagocytosis in the mononuclear phagocytic s
Publikováno v:
Journal of Thrombosis and Haemostasis. 7:245-248
Intravenous immunoglobulin (IVIg) is used to treat an ever-increasing number of autoimmune diseases. While the exact mechanism of action of IVIg has remained elusive, many theories have been suggested, including mononuclear phagocytic system blockade
Autor:
Vinayakumar Siragam, Andrew R. Crow, John Freedman, Alan H. Lazarus, Hoang Le-Tien, Davor Brinc
Publikováno v:
The Journal of Immunology. 181:948-953
Hemolytic disease of the fetus and newborn can be effectively prevented by administration of anti-D to the mother. The administered IgG results in the attenuation of RBC-specific Ab production, a process termed Ab-mediated immune suppression (AMIS).
Publikováno v:
ISBT Science Series. 3:152-158
Publikováno v:
British Journal of Haematology. 139:275-279
Haemolytic disease of the newborn (HDN) can be prevented by the passive administration of anti-D to the mother. The most accepted theory to describe this activity of anti-D is based upon its ability to clear opsonized erythrocytes before their recogn
Publikováno v:
Acta Paediatrica. 87:21-25
Adult chronic idiopathic thrombocytopenic purpura (ITP) is an autoimmune disease characterized by production of autoreactive antibodies to platelet antigens. It is now becoming clear that autoantibody production, in general, is regulated by T helper
Publikováno v:
Blood. 109:155-158
The exact mechanism of action of IVIg in the amelioration of immune thrombocytopenic purpura (ITP) is still unclear. Studies have suggested that IVIg may function through the regulation of cytokines, including interleukin-1 receptor antagonist (IL-1R