Effective decellularisation of human saphenous veins for biocompatible arterial tissue engineering applications: Bench optimisation and feasibility in vivo testing

Autor: Nadiah S Sulaiman, Andrew R Bond, Vito D Bruno, John Joseph, Jason L Johnson, M-Saadeh Suleiman, Sarah J George, Raimondo Ascione

Publikováno v: Journal of Tissue Engineering, Vol 12 (2021)

Human saphenous vein (hSV) and synthetic grafts are commonly used conduits in vascular grafting, despite high failure rates. Decellularising hSVs (D-hSVs) to produce vascular scaffolds might be an effective alternative. We assessed the effectiveness

Externí odkaz: https://doaj.org/article/62046e31c2f54310850ddd8ac08b28b9

Plaque Size Is Decreased but M1 Macrophage Polarization and Rupture Related Metalloproteinase Expression Are Maintained after Deleting T-Bet in ApoE Null Mice.

Autor: Aikaterini Tsaousi, Elaine M Hayes, Karina Di Gregoli, Andrew R Bond, Laura Bevan, Anita C Thomas, Andrew C Newby

Publikováno v: PLoS ONE, Vol 11, Iss 2, p e0148873 (2016)

BACKGROUND:Thelper1 (Th1) lymphocytes have been previously implicated in atherosclerotic plaque growth but their role in plaque vulnerability to rupture is less clear. We investigated whether T-bet knockout that prevents Th1 lymphocyte differentiatio

Externí odkaz: https://doaj.org/article/55f6eff7c91b40f5b0acfdfc775ade44

Hearts from mice fed a non-obesogenic high-fat diet exhibit changes in their oxidative state, calcium and mitochondria in parallel with increased susceptibility to reperfusion injury.

Autor: Ben Littlejohns, Philippe Pasdois, Simon Duggan, Andrew R Bond, Kate Heesom, Christopher L Jackson, Gianni D Angelini, Andrew P Halestrap, M-Saadeh Suleiman

Publikováno v: PLoS ONE, Vol 9, Iss 6, p e100579 (2014)

High-fat diet with obesity-associated co-morbidities triggers cardiac remodeling and renders the heart more vulnerable to ischemia/reperfusion injury. However, the effect of high-fat diet without obesity and associated co-morbidities is presently unk

Externí odkaz: https://doaj.org/article/df9dab9275f54eb1904a4e874a09670a

Effective decellularisation of human saphenous veins for biocompatible arterial tissue engineering applications: Bench optimisation and feasibility in vivo testing

Autor: M-Saadeh Suleiman, John Joseph, Andrew R Bond, Vito Domenico Bruno, Sarah J George, Nadiah Sulaiman, Jason L. Johnson, Raimondo Ascione

Publikováno v: Journal of Tissue Engineering, Vol 12 (2021)
Sulaiman, N S, Bond, A R, Bruno, V D, Joseph, J, Johnson, J L, Suleiman, M-S, George, S J & Ascione, R 2021, ' Effective decellularisation of human saphenous veins for biocompatible arterial tissue engineering applications : Bench optimisation and feasibility in vivo testing ', Journal of Tissue Engineering, vol. 12, 2041731420987529 . https://doi.org/10.1177/2041731420987529
Journal of Tissue Engineering

Human saphenous vein (hSV) and synthetic grafts are commonly used conduits in vascular grafting, despite high failure rates. Decellularising hSVs (D-hSVs) to produce vascular scaffolds might be an effective alternative. We assessed the effectiveness

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a1597c1a8cdc4b0b76ff3122bbef988
https://doaj.org/article/62046e31c2f54310850ddd8ac08b28b9

Manganese-enhanced MRI: comparison of agents in the rat pancreas

Autor: Lucy E Kershaw, Alexandra R. Roberts, Rob Janiczek, Shareen Forbes, Antonella Napolitano, Andrew R Bond, Scott Semple, Pilar Jimenez-Royo, David M.L. Lilburn, Philip S. Murphy, Maurits A. Jansen, Salamah Mohammad Alwahsh

Publikováno v: Kershaw, L E, Lilburn, D M, Jansen, M A, Bond, A R, Alwahsh, S M, Jimenez-royo, P, Napolitano, A, Murphy, P, Roberts, A, Robjaniczek,, Forbes, S & Semple, S I 2020, ' Manganese-enhanced MRI: comparison of agents in the rat pancreas ', Journal of Magnetic Resonance Open, pp. 100002 . https://doi.org/10.1016/j.jmro.2020.100002
Journal of Magnetic Resonance Open, Vol 1, Iss, Pp 100002-(2019)

Mangafodipir was approved for use as an MRI contrast agent in the late 1990s for liver and pancreas imaging but it was removed from the European market for commercial reasons in 2012. Previously, preliminary work in mice and in diabetic patients show

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12fd339801380046b8a33199b7d9f5e9
https://www.pure.ed.ac.uk/ws/files/151369550/1_s2.0_S2666441020300029_main.pdf