Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Andrew R, Williams"'
Autor:
Audrey Inge Schytz Andersen-Civil, Pankaj Arora, Ling Zhu, Laura J. Myhill, Nilay Büdeyri Gökgöz, Josue L. Castro-Mejia, Milla M. Leppä, Lars H. Hansen, Jacob Lessard-Lord, Juha-Pekka Salminen, Stig M. Thamsborg, Dennis Sandris Nielsen, Yves Desjardins, Andrew R. Williams
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Polyphenols are phytochemicals commonly found in plant-based diets which have demonstrated immunomodulatory and anti-inflammatory properties. However, the interplay between polyphenols and pathogens at mucosal barrier surfaces has not yet been elucid
Externí odkaz:
https://doaj.org/article/233c6a6acbed41518fd7900f4017b093
Autor:
Charlotte Smith Bonde, Helena Mejer, Laura J. Myhill, Ling Zhu, Penille Jensen, Nilay Büdeyri Gökgöz, Lukasz Krych, Dennis Sandris Nielsen, Kerstin Skovgaard, Stig Milan Thamsborg, Andrew R. Williams
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Brown seaweeds have a rich bioactive content known to modulate biological processes, including the mucosal immune response and microbiota function, and may therefore have the potential to control enteric pathogens. Here, we tested if dietary
Externí odkaz:
https://doaj.org/article/3040d3b755d1471f839e92bcb36803c6
Autor:
Angela H. Valente, Karen M. R. Jensen, Laura J. Myhill, Ling Zhu, Caroline M. J. Mentzel, Lukasz Krych, Henrik T. Simonsen, Josue L. Castro-Mejía, Alex Gobbi, Knud Erik Bach Knudsen, Dennis S. Nielsen, Stig M. Thamsborg, Andrew R. Williams
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background The influence of diet on immune function and resistance to enteric infection and disease is becoming ever more established. Highly processed, refined diets can lead to inflammation and gut microbiome dysbiosis, whilst health-promo
Externí odkaz:
https://doaj.org/article/424ae6d16692466fa29bd877b07a6eb4
Autor:
Nathalie Acevedo, Ana Lozano, Josefina Zakzuk, Kevin Llinás-Caballero, David Brodin, Peter Nejsum, Andrew R. Williams, Luis Caraballo
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundAscaris lumbricoides cystatin (Al-CPI) prevents the development of allergic airway inflammation and dextran-induced colitis in mice models. It has been suggested that helminth-derived cystatins inhibit cathepsins in dendritic cells (DC), bu
Externí odkaz:
https://doaj.org/article/a9d51a70d2224ea4b19bed7ff98a9752
Autor:
Helene Israelson, Amalie Vedsted-Jakobsen, Ling Zhu, Aurelie Gagnaire, Alexandra von Münchow, Nina Polakovicova, Angela H. Valente, Ali Raza, Audrey I. S. Andersen-Civil, John E. Olsen, Laura J. Myhill, Peter Geldhof, Andrew R. Williams
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Diet composition plays a large role in regulating gut health and enteric infection. In particular, synthetic “Western-style” diets may predispose to disease, while whole-grain diets containing high levels of crude fiber are thought to pr
Externí odkaz:
https://doaj.org/article/8e0eeb2c6bf54fd3b98aaefec31e55b8
Autor:
Miguel Peña-Espinoza, Yeambell Romero-Uzqueda, Angela H. Valente, Matthew de Roode, Henrik T. Simonsen, Stig M. Thamsborg, Andrew R. Williams, Rodrigo López-Muñoz
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 20, Iss , Pp 43-53 (2022)
Chagas disease, caused by the protozoa Trypanosoma cruzi, is a potentially life-threatening parasitic zoonosis infecting 6–7 million people worldwide, mainly in Latin America. Due to the limited numbers of drugs available against this neglected dis
Externí odkaz:
https://doaj.org/article/cb66f6511bf248cba1e8d950b0f98cfd
Autor:
Audrey Inge Schytz Andersen-Civil, Milla Marleena Leppä, Stig M. Thamsborg, Juha-Pekka Salminen, Andrew R. Williams
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Andersen-Civil et al isolated a range of proanthocyanidin (PAC) polymer mixtures from plant material and demonstrated that polymer size was a key determinant of the ability of PACs to regulate inflammatory responses in murine macrophages, and intesti
Externí odkaz:
https://doaj.org/article/9f7678958b34441e839b880a3cb7d8c6
Autor:
Angela H. Valente, Matthew de Roode, Madeleine Ernst, Miguel Peña-Espinoza, Louis Bornancin, Charlotte S. Bonde, María Martínez-Valladares, Sabrina Ramünke, Jürgen Krücken, Henrik T. Simonsen, Stig M. Thamsborg, Andrew R. Williams
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 15, Iss , Pp 105-114 (2021)
Increasing resistance towards anthelmintic drugs has necessitated the search for alternative treatments for the control of gastrointestinal nematode parasites. Animals fed on chicory (Cichorium intybus L.), a temperate (pasture) crop, have reduced pa
Externí odkaz:
https://doaj.org/article/f2991e8f16ac47349d19e0ef6c3edf38
Publikováno v:
Pathogens, Vol 12, Iss 6, p 755 (2023)
ABC transporters, a family of ATP-dependent transmembrane proteins, are responsible for the active transport of a wide range of molecules across cell membranes, including drugs, toxins, and nutrients. Nematodes possess a great diversity of ABC transp
Externí odkaz:
https://doaj.org/article/ff4551f5916a458293279c2dbb324fcb
Publikováno v:
Pathogens, Vol 12, Iss 4, p 536 (2023)
Enteric helminth infection is an increasing concern in companion animals due to reports of resistance to commonly used anthelmintic drugs. Thus, the assessment of new therapeutic options such as bioactive dietary additives is of high importance. Here
Externí odkaz:
https://doaj.org/article/f99890e734584331aed02ff517dd77ee