Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Andrew R, Harris"'
Publikováno v:
Heliyon, Vol 10, Iss 19, Pp e38214- (2024)
Atomic Force Microscopy (AFM) has become the gold standard tool for measuring mechanical properties of biological samples including proteins, single cells and tissues. However, investment in this specialized equipment and gaining expertise in its ope
Externí odkaz:
https://doaj.org/article/2507ebe0fcb14d458f5ca6212ca9aeef
Autor:
Sarah Desroches, Andrew R. Harris
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
The actin cytoskeleton plays a pivotal role in a broad range of physiological processes including directing cell shape and subcellular organization, determining cell mechanical properties, and sensing and transducing mechanical forces. The versatilit
Externí odkaz:
https://doaj.org/article/51750a4691fb44e3a6e484124ad04fb0
Autor:
Andrew R. Harris, Pamela Jreij, Brian Belardi, Aaron M. Joffe, Andreas R. Bausch, Daniel A. Fletcher
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The assembly of actin filaments into distinct cytoskeletal structures plays a critical role in cell physiology. Here, the authors use a combination of live cell imaging and in vitro single molecule binding measurements to show that tandem calponin ho
Externí odkaz:
https://doaj.org/article/ae02da38c3004ec79edd58117dec2542
Autor:
Kevin R Fingerman, Jerome Qiriazi, Cassidy L Barrientos, Max Blasdel, Jeffrey M Comnick, Andrew R Harris, Carisse Geronimo, Chih-Wei Hsu, Jeffrey M Kane, Elaine Oneil, Sabrinna Rios-Romero, Luke W Rogers, Mark Severy, Micah C Wright
Publikováno v:
Environmental Research Letters, Vol 18, Iss 3, p 034038 (2023)
California faces crisis conditions on its forested landscapes. A century of aggressive logging and fire suppression in combination with conditions exacerbated by climate change have created an ongoing ecological, economic, and public health emergency
Externí odkaz:
https://doaj.org/article/2a7b054a4313434ab1adcc2a08ba757c
Autor:
Emily C. Suter, Eva M. Schmid, Andrew R. Harris, Erik Voets, Brian Francica, Daniel A. Fletcher
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109587- (2021)
Summary: Cancer immunotherapies often modulate macrophage effector function by introducing either targeting antibodies that activate Fcγ receptors (FcγRs) or blocking antibodies that disrupt inhibitory SIRPα-CD47 engagement. However, how these com
Externí odkaz:
https://doaj.org/article/a86f2ef7a8184348b1f2465c0e30cb2b
Autor:
Adam J. Stevens, Andrew R. Harris, Josiah Gerdts, Ki H. Kim, Coralie Trentesaux, Jonathan T. Ramirez, Wesley L. McKeithan, Faranak Fattahi, Ophir D. Klein, Daniel A. Fletcher, Wendell A. Lim
Publikováno v:
Nature, vol 614, iss 7946
Cell adhesion molecules are ubiquitous in multicellular organisms, specifying precise cell–cell interactions in processes as diverse as tissue development, immune cell trafficking and the wiring of the nervous system1–4. Here we show that a wide
Autor:
Andreas R. Bausch, Andrew R. Harris, Pamela Jreij, Kathy Y. Wei, Brian Belardi, Hengameh Shams, Daniel A. Fletcher
Publikováno v:
Molecular biology of the cell, vol 30, iss 26
Molecular Biology of the Cell
Molecular Biology of the Cell
Tandem calponin homology domains are common actin-binding motifs found in proteins such as α-actinin, filamin, utrophin, and dystrophin that organize actin filaments into functional structures. Despite a conserved structural fold and regions of high
Autor:
Chunyu Zhao, Abdul Bhuiya, Jennifer A. Doudna, Melanie Ott, Emeric J Charles, Ming X. Tan, Brittney W. Thornton, Patrick D. Hsu, Amanda Mok, Arturo M. Escajeda, María Díaz de León Derby, Katherine S. Pollard, Daniel A. Fletcher, David F. Savage, G. Renuka Kumar, Noam Prywes, Tina Y. Liu, Dylan C. J. Smock, Shineui Kim, John J Desmarais, Eli J Dugan, Parinaz Fozouni, Sungmin Son, Liana F. Lareau, Neil A. Switz, Andrew R. Harris, Stephanie I. Stephens, Maxim Armstrong, Jeffrey Shu, Shrutee Jakhanwal, Anthony T. Iavarone, Roger McIntosh, Shreeya Agrawal, Gavin J. Knott
Publikováno v:
Nat Chem Biol
Nature Chemical Biology
medRxiv
article-version (status) pre
article-version (number) 1
Nature Chemical Biology
medRxiv
article-version (status) pre
article-version (number) 1
Direct, amplification-free detection of RNA has the potential to transform molecular diagnostics by enabling simple on-site analysis of human or environmental samples. CRISPR-Cas nucleases offer programmable RNA-guided RNA recognition that triggers c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c785d1b2d3e9f64e47f040660076a9bd
https://europepmc.org/articles/PMC10184463/
https://europepmc.org/articles/PMC10184463/
Autor:
Eva M. Schmid, Daniel A. Fletcher, Emily C. Suter, Andrew R. Harris, Erik Voets, Brian Francica
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109587-(2021)
Cell reports
Cell reports, vol 36, iss 8
Cell reports
Cell reports, vol 36, iss 8
SUMMARY Cancer immunotherapies often modulate macrophage effector function by introducing either targeting antibodies that activate Fcγ receptors (FcγRs) or blocking antibodies that disrupt inhibitory SIRPα-CD47 engagement. However, how these comp
Autor:
Bastian Joehnk, Sungmin Son, Gavin J. Knott, Chia-Lin Tsou, Keith Walcott, Melanie Ott, Maxim Armstrong, Charles Langelier, Parinaz Fozouni, G. Renuka Kumar, Pei Yi Chen, Jeannette M. Osterloh, María Díaz de León Derby, Andrew R. Harris, Amy Kistler, Carley N. Gray, Chunyu Zhao, Maira Phelps, Emily D. Crawford, Anke Meyer-Franke, Andreas S. Puschnik, Stephanie I. Stephens, Abdul Bhuiya, Daniel A. Fletcher, Jeffrey Shu, Neil A. Switz, Daniela Boehm, Katherine S. Pollard, Joseph L. DeRisi, Michael V. D’Ambrosio, Jennifer A. Doudna, Anita Sil
Publikováno v:
Cell
Cell, vol 184, iss 2
Cell, vol 184, iss 2
The December 2019 outbreak of a novel respiratory virus, SARS-CoV-2, has become an ongoing global pandemic due in part to the challenge of identifying symptomatic, asymptomatic, and pre-symptomatic carriers of the virus. CRISPR diagnostics can augmen