Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Andrew Protheroe"'
Autor:
John McGrane, Ricky Frazer, Amarnath Challapalli, Gihan Ratnayake, Zhaung Boh, Alison Clayton, Caroline Chau, Anand Sharma, Manal Elgendy, Natalie Charnley, Wael Mohamed, Sarah Kingdon, Andrew Protheroe, Anna Lydon, Anna Halstead, Vicky Ford, Iqtedar Muazzam, Dawn Lee, G. J. Melendez‐Torres, Amit Bahl
Publikováno v:
Cancer Medicine, Vol 13, Iss 12, Pp n/a-n/a (2024)
Abstract Introduction Clinical trials show improved progression‐free survival (PFS) and overall survival (OS) in first‐line metastatic renal cell carcinoma (mRCC) patients with immunotherapy containing systemic anti‐cancer therapies (SACT). How
Externí odkaz:
https://doaj.org/article/048d2238b38645769fc48b7be6b8ca68
Autor:
Janet Brown, Brooke Harrow, Anne Marciniak, Christine McCarthy, Aude Houchard, Lori Cirneanu, Andrew Protheroe
Publikováno v:
Drugs - Real World Outcomes, Vol 11, Iss 2, Pp 195-207 (2024)
Abstract Background and Objective The tyrosine kinase inhibitors cabozantinib and axitinib have been widely used in England to treat advanced renal cell carcinoma following prior vascular endothelial growth factor-targeted therapy, but data on real-w
Externí odkaz:
https://doaj.org/article/82bbb121fd2349b08c067d0b6d0b35bf
Autor:
Thomas Starkey, Maria C. Ionescu, Michael Tilby, Martin Little, Emma Burke, Matthew W. Fittall, Sam Khan, Justin K. H. Liu, James R. Platt, Rosie Mew, Arvind R. Tripathy, Isabella Watts, Sophie Therese Williams, Nathan Appanna, Youssra Al-Hajji, Matthew Barnard, Liza Benny, Alexander Burnett, Jola Bytyci, Emma L. Cattell, Vinton Cheng, James J. Clark, Leonie Eastlake, Kate Gerrand, Qamar Ghafoor, Simon Grumett, Catherine Harper-Wynne, Rachel Kahn, Alvin J. X. Lee, Oliver Lomas, Anna Lydon, Hayley Mckenzie, NCRI Consumer Forum, Hari Panneerselvam, Jennifer S. Pascoe, Grisma Patel, Vijay Patel, Vanessa A. Potter, Amelia Randle, Anne S. Rigg, Tim M. Robinson, Rebecca Roylance, Tom W. Roques, Stefan Rozmanowski, René L. Roux, Ketan Shah, Remarez Sheehan, Martin Sintler, Sanskriti Swarup, Harriet Taylor, Tania Tillett, Mark Tuthill, Sarah Williams, Yuxin Ying, Andrew Beggs, Tim Iveson, Siow Ming Lee, Gary Middleton, Mark Middleton, Andrew Protheroe, Tom Fowler, Peter Johnson, Lennard Y. W. Lee
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Patients with cancer are at increased risk of hospitalisation and mortality following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, the SARS-CoV-2 phenotype evolution in patients with cancer since 2020 has
Externí odkaz:
https://doaj.org/article/b2a7d9f7273c4fa49fa236821ef7154d
Autor:
Srinivasa R. Rao, Andrew Protheroe, Lucia Cerundolo, David Maldonado-Perez, Lisa Browning, Alastair D. Lamb, Richard J. Bryant, Ian G. Mills, Dan J. Woodcock, Freddie C. Hamdy, Ian P. M. Tomlinson, Clare Verrill
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12722 (2023)
Prostate cancer is typically of acinar adenocarcinoma type but can occasionally present as neuroendocrine and/or ductal type carcinoma. These are associated with clinically aggressive disease, and the former often arises on a background of androgen d
Externí odkaz:
https://doaj.org/article/3dc858a542854e47aba148547ce1d7ed
Autor:
Stephan Ursprung, Helen Mossop, Ferdia A. Gallagher, Evis Sala, Richard Skells, Jamal A. N. Sipple, Thomas J. Mitchell, Anita Chhabra, Kate Fife, Athena Matakidou, Gemma Young, Amanda Walker, Martin G. Thomas, Mireia Crispin Ortuzar, Mark Sullivan, Andrew Protheroe, Grenville Oades, Balaji Venugopal, Anne Y. Warren, John Stone, Tim Eisen, James Wason, Sarah J. Welsh, Grant D. Stewart
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Window-of-opportunity trials, evaluating the engagement of drugs with their biological target in the time period between diagnosis and standard-of-care treatment, can help prioritise promising new systemic treatments for later-pha
Externí odkaz:
https://doaj.org/article/c51c1579691f49dabf5c4459307d8325
Autor:
Karin Purshouse, Sarah Chamberlain, Maria Soares, Mark Tuthill, Andrew Protheroe, David R. Mole
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-6 (2019)
Abstract Background Patients with metastatic renal carcinoma frequently have pre-existing renal impairment and not infrequently develop worsening renal function as a complication of their treatment. The presence of pancreatic metastases in patients w
Externí odkaz:
https://doaj.org/article/d2b0c6a624ba4947bd9bccfcfb3c41e8
Autor:
Kai Rakovic, Richard Colling, Lisa Browning, Monica Dolton, Margaret R. Horton, Andrew Protheroe, Alastair D. Lamb, Richard J. Bryant, Richard Scheffer, James Crofts, Ewart Stanislaus, Clare Verrill
Publikováno v:
Diagnostics, Vol 12, Iss 5, p 1225 (2022)
There has been particular interest in the deployment of digital pathology (DP) and artificial intelligence (AI) in the diagnosis of prostate cancer, but little is known about the views of the public on their use. Prostate Cancer UK supporters were in
Externí odkaz:
https://doaj.org/article/a0d50451df7243d296850f599a640310
Autor:
Andrew Protheroe, Pedro J Romero, Richard Bryant, Lucy Carter, Julianne Hollidge, Ian Poulton, Megan Baker, Celia Mitton, Andrea Baines, Armin Meier, Richard Harrop, Ruth MacPherson, Steven Kennish, Susan Morgan, Selena Vigano, James Catto, Adrian V S Hill
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Prostate cancer (PCa) has been under investigation as a target for antigen-specific immunotherapies in metastatic disease settings for the last two decades leading to a licensure of the first therapeutic cancer vaccine, Sipuleucel-T, in 20
Externí odkaz:
https://doaj.org/article/868557a8fdb8438aa71d8b212334c883
Autor:
Richard Colling, Andrew Protheroe, Mark Sullivan, Ruth Macpherson, Mark Tuthill, Jacqueline Redgwell, Zoe Traill, Angus Molyneux, Elizabeth Johnson, Niveen Abdullah, Andrea Taibi, Nikki Mercer, Harry R. Haynes, Anthony Sackville, Judith Craft, Joao Reis, Gabrielle Rees, Maria Soares, Ian S. D. Roberts, Darrin Siiankoski, Helen Hemsworth, Derek Roskell, Sharon Roberts-Gant, Kieron White, Jens Rittscher, Jim Davies, Lisa Browning, Clare Verrill
Publikováno v:
Diagnostics, Vol 11, Iss 12, p 2191 (2021)
Background: In this article we share our experience of creating a digital pathology (DP) supraregional germ cell tumour service, including full digitisation of the central laboratory. Methods: DP infrastructure (Philips) was deployed across our hospi
Externí odkaz:
https://doaj.org/article/3ca0341550b64a49b16959b7daed5916
Autor:
Abhisek Ghosh, Korsuk Sirinukunwattana, Nasullah Khalid Alham, Lisa Browning, Richard Colling, Andrew Protheroe, Emily Protheroe, Stephanie Jones, Alan Aberdeen, Jens Rittscher, Clare Verrill
Publikováno v:
Cancers, Vol 13, Iss 6, p 1325 (2021)
Testicular cancer is the most common cancer in men aged from 15 to 34 years. Lymphovascular invasion refers to the presence of tumours within endothelial-lined lymphatic or vascular channels, and has been shown to have prognostic significance in test
Externí odkaz:
https://doaj.org/article/8d7d12ccb38f4d2eb4f9e1af6d3e9f02