Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Andrew Podd"'
Autor:
Yinghong He, Guoping Fu, Wasif N. Khan, Jacqueline A. Wright, Yuhong Chen, Andrew Podd, Renren Wen, Eden Kleiman, Demin Wang, Mei Yu
Publikováno v:
The Journal of Immunology. 189:5185-5193
Anergy is a key physiological mechanism for restraining self-reactive B cells. A marked portion of peripheral B cells are anergic B cells that largely depend on BAFF for survival. BAFF activates the canonical and noncanonical NF-κB pathways, both of
Autor:
Roza Nurieva, Xiaopeng Qi, Renren Wen, Stephanie S. Watowich, Junmei Wang, Hua Huang, Mei Yu, Andrei Alekseev, Chen Dong, Yuhong Chen, Haiyan S. Li, Demin Wang, Hai Qi, Andrew Podd
Publikováno v:
Journal of Biological Chemistry. 287:11234-11239
Recent work has identified a new subset of CD4(+) T cells named as Tfh cells that are localized in germinal centers and critical in germinal center formation. Tfh cell differentiation is regulated by IL-6 and IL-21, possibly via STAT3 factor, and B c
Autor:
Gowthami M. Arepally, Liudi Yuan, Andrew Podd, Yongwei Zheng, Demin Wang, Mei Yu, Debra K. Newman, Renren Wen
Heparin-induced thrombocytopenia (HIT) is an immune-mediated disorder that can cause fatal arterial or venous thrombosis/thromboembolism. Immune complexes consisting of platelet factor 4 (PF4), heparin, and PF4/heparin-reactive antibodies are central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2080152d0501b85ee31cc76c3d7b8151
https://europepmc.org/articles/PMC3637017/
https://europepmc.org/articles/PMC3637017/
Autor:
Sandra L. Haberichter, Tricia L Slobodianuk, Veronica H. Flood, Andrew Podd, Kenneth D. Friedman
Publikováno v:
Blood. 126:1090-1090
Laboratory testing of von Willebrand disease (VWD) continues to be a complicated and much debated subject. There are multiple tests recommended to assess varying aspects of von Willebrand factor (VWF) function, and no single test that identifies all
Autor:
Zhijian J. Chen, James Schuman, Mei Yu, Demin Wang, Andrew Podd, Yuhong Chen, Renren Wen, Hong Hsing Liu
The kinase TAK1 is essential for T-cell receptor (TCR)–mediated nuclear factor κB (NF-κB) activation and T-cell development. However, the role of TAK1 in B-cell receptor (BCR)–mediated NF-κB activation and B-cell development is not clear. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::375ee14462eb989e3d5aed31e52b648a
https://europepmc.org/articles/PMC2680363/
https://europepmc.org/articles/PMC2680363/
Autor:
Mei Yu, Magdalena Chrzanowska-Wodnicka, Gilbert C. White, Yuhong Chen, Andrew Podd, Demin Wang, Renren Wen
B-cell development is orchestrated by complex signaling networks. Rap1 is a member of the Ras superfamily of small GTP-binding proteins and has 2 isoforms, Rap1a and Rap1b. Although Rap1 has been suggested to have an important role in a variety of ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db7e6b9012f53fc8ef909bb75533283
https://europepmc.org/articles/PMC2343596/
https://europepmc.org/articles/PMC2343596/
Autor:
Geqiang Li, Renren Wen, Demin Wang, Lie Di, Xuezhi Dai, Lothar Hennighausen, Andrew Podd, Kevin D. Bunting, Yuhong Chen
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 179(2)
The two closely related Stat5 (Stat5A and Stat5B) proteins are activated by a broad spectrum of cytokines. However, with the complication of the involvement of Stat5A/5B in stem cell function, the role of Stat5A/5B in the development and function of
Publikováno v:
Blood. 124:1548-1548
Dabigatran is a potent, competitive, and reversible direct thrombin inhibitor, that binds to the active site of thrombin, inhibiting both free and clot-bound thrombin. It is the active form of dabigatran etexilate, which is a low molecular weight pro
Autor:
Yongwei Zheng, Mei Yu, Andrew Podd, Debra K. Newman, Renren Wen, Gowthami M Arepally, Demin Wang
Publikováno v:
Blood. 120:1175-1175
Abstract 1175 Heparin-induced thrombocytopenia (HIT) is an immune-mediated disorder that can cause fatal arterial or venous thrombosis/thromboembolism. Immune complexes consisting of platelet factor 4 (PF4), heparin and PF4/heparin-reactive antibodie
Publikováno v:
The Journal of Immunology. 188:121.19-121.19
Recent work has identified a new subset of CD4+ T cells named as T follicular helper (Tfh) cells that are localized in germinal centers and critical in germinal-center formation. Tfh cell differentiation is regulated by IL-6 and IL-21, possibly via S