Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Andrew Palma"'
Autor:
Andrew Palma, Robert Newcomb
Publikováno v:
Brain Research. 638:95-102
omega-Conopeptides are antagonists of subtypes of neuronal calcium channels. Two omega-conopeptides, SVIB and MVIIC, have recently been identified which have a novel specificity for these ionophores. We have tested the actions these peptides, as well
Publikováno v:
The Journal of Membrane Biology. 120:67-73
We have examined the effects of changing extracellular pH on the function of nicotinic acetylcholine receptors from Torpedo californica using ion flux and electrophysiological methods. Agonist-induced cation efflux from vesicles containing purified,
Publikováno v:
Biophysical Journal. 62:61-63
McNamee, 1991). cDNA cloning reveals that each subunit has four homologous hydrophobic segments (Ml, M2, M3, and M4) that are believed to span the lipid bilayer. There is strong evidence that M2 is the ion channel-lining domain, but the specific func
Autor:
Andrew Palma, Katalin Tarczy-Hornoch, Balazs G. Szoke, Cong Ruth, James A. Miller, Gang Wang, David J. Dooley, Joseph A. Loo, George P. Miljanich, Robert Newcomb, Laszlo Urge, Xiao-hua Chen, William F. Hopkins, Richard W. Tsien, Laszlo Nadasdi, José R. Lemos
Publikováno v:
Biochemistry. 37(44)
We describe the first potent and selective blocker of the class E Ca2+channel. SNX-482, a novel 41 amino acid peptide present in the venom of the African tarantula, Hysterocrates gigas, was identified through its ability to inhibit human class E Ca2+
Autor:
Andrew Palma, Robert Newcomb, J.R. Bell, Daniel C. Chung, Laszlo Nadasdi, K Lau, J Fox, B Horne, Cong Ruth, S. Gaur
Publikováno v:
Biochemistry. 34(26)
A novel selective calcium channel antagonist peptide, SNX-325, has been isolated from the venom of the spider Segestria florentina. The peptide was isolated using as bioassays the displacement of radioiodinated omega-conopeptide SNX-230 (MVIIC) from
Publikováno v:
Cellular and molecular neurobiology. 10(3)
1. Nicotinic acetylcholine receptors (nAChR) from BC3H1 cells (which express a skeletal muscle-type receptor) and fromTorpedo californica electric organ were expressed inXenopus laevis oocytes and studied with a voltage-clamp technique. 2. We found t
Publikováno v:
Biochemistry. 29(23)
Previous chemical modification studies of the acetylcholine receptor [Yee, A.S., Corey, D.E., & McNamee, M.G. (1986) Biochemistry 25, 2110-2119] were extended by using fluorescent N-pyrenylmaleimide to alkylate purified Torpedo californica nicotinic