Zobrazeno 1 - 10
of 223
pro vyhledávání: '"Andrew P. Somlyo"'
Autor:
John D. Matthew, Shizhen Luo, Avril V. Somlyo, Andra S. Stevenson, Andrew P. Somlyo, Masumi Eto
Publikováno v:
FEBS Letters. 578:73-79
Ca2+-sensitization of smooth muscle occurs through inhibition of myosin light chain phosphatase (MLCP) leading to an increase in the MLCK:MLCP activity ratio. MLCP is inhibited through phosphorylation of its regulatory subunit (MYPT-1) following acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f5ffaba1cf4f214e20471f790dae8b
https://doi.org/10.1016/j.febslet.2004.10.072
https://doi.org/10.1016/j.febslet.2004.10.072
Autor:
Avril V. Somlyo, Andrew P. Somlyo
Publikováno v:
Journal of Muscle Research and Cell Motility. 25:583-621
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb4fa910284f03740ef743dabfa6bc50
https://doi.org/10.1007/s10974-004-3146-1
https://doi.org/10.1007/s10974-004-3146-1
Autor:
David R. Trentham, Avril V. Somlyo, Alexander S. Khromov, Martin R. Webb, Andrew P. Somlyo, Michael A. Ferenczi
Publikováno v:
Biophysical Journal. 86:2318-2328
The effects of myosin regulatory light chain (RLC) phosphorylation and strain on adenosine diphosphate (ADP) release from cross-bridges in phasic (rabbit bladder (Rbl)) and tonic (femoral artery (Rfa)) smooth muscle were determined by monitoring fluo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652fb3decf2c6bb128c9e3e1bee9b872
https://doi.org/10.1016/s0006-3495(04)74289-7
https://doi.org/10.1016/s0006-3495(04)74289-7
Publikováno v:
Journal of Biological Chemistry. 278:39892-39896
The purpose of this study was to determine whether steric blockage of one head by the second head of native two-headed myosin was responsible for the inactivity of nonphosphorylated two-headed myosin compared with the high activity of single-headed m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ace4a166803ecfdca45130f8ac9e8b1d
https://doi.org/10.1074/jbc.m306094200
https://doi.org/10.1074/jbc.m306094200
Autor:
Clayton P. Phelps, Andrew P. Somlyo, Avril V. Somlyo, Mary C. Beckerle, Isabelle Gorenne, Robert K. Nakamoto
Publikováno v:
American Journal of Physiology-Cell Physiology. 285:C674-C685
An 80-kDa protein, prominently expressed in smooth muscle, was microsequenced and identified as LPP, the product of the lipoma-preferred partner gene (Petit MMR, Mols R, Schoenmakers EFPM, Mandahl N, and Van de Ven WJM. Genomics 36: 118-129, 1996). U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4e3b75985ac3f7a52ae28ded38dc66
https://doi.org/10.1152/ajpcell.00608.2002
https://doi.org/10.1152/ajpcell.00608.2002
Autor:
Avril V. Somlyo, Joseph G. Akar, Joseph Craft, Andrew P. Somlyo, Ruoya Ho, David E. Haines, Thomas H. Everett
Publikováno v:
Circulation. 107:1810-1815
Background— Ion channel remodeling occurs during atrial fibrillation (AF); however, the extent of alteration in the subcellular distribution of elements (Na, K, Cl, Ca, Mg, P) is unknown. Electron probe microanalysis was used to determine the total
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82484393fb0555d3bcb9096f76aa6524
https://doi.org/10.1161/01.cir.0000058462.23347.93
https://doi.org/10.1161/01.cir.0000058462.23347.93
Autor:
Charles G. diPierro, Masumi Eto, Matthew Barrett, Paul W. Read, Andrew P. Somlyo, Clayton P. Phelps, Avril V. Somlyo, Jennifer J. Gibson, Charles E. Myers, M. Christine Burnitz
Publikováno v:
The FASEB Journal. 17:223-234
The purpose of this study was to determine the effects of inhibitors of Rho kinase (ROK) and matrix metalloproteinases (MMPs) on angiogenesis and tumor growth and to evaluate ROK activity in human prostate cancer PC3 cells and endothelial cells (HUVE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71cb1060160c29c7c689546018aa4356
https://doi.org/10.1096/fj.02-0655com
https://doi.org/10.1096/fj.02-0655com
Publikováno v:
Journal of Biological Chemistry. 277:12479-12485
Binding of the urokinase-type plasminogen activator (uPA) to its receptor activates diverse cell signaling pathways. How these signals are integrated so that cell physiology is altered remains unclear. In this study, we demonstrated that migration of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd426561dde1e3fa8eb59b51dd25b34
https://doi.org/10.1074/jbc.m111147200
https://doi.org/10.1074/jbc.m111147200