Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Andrew P. Morokoff"'
Autor:
Sarah F. Stuart, Peter Curpen, Adele J. Gomes, Michelle C. Lan, Shuai Nie, Nicholas A. Williamson, George Kannourakis, Andrew P. Morokoff, Adrian A. Achuthan, Rodney B. Luwor
Publikováno v:
Brain Sciences, Vol 14, Iss 1, p 89 (2024)
Glioblastoma is highly proliferative and invasive. However, the regulatory cytokine networks that promote glioblastoma cell proliferation and invasion into other areas of the brain are not fully defined. In the present study, we define a critical rol
Externí odkaz:
https://doaj.org/article/67b463ca5fd74a849d24bbbf4752968b
Autor:
Sarah F. Stuart, Ayenachew Bezawork-Geleta, Zammam Areeb, Juliana Gomez, Vanessa Tsui, Ahmad Zulkifli, Lucia Paradiso, Jordan Jones, Hong P. T. Nguyen, Tracy L. Putoczki, Paul V. Licciardi, George Kannourakis, Andrew P. Morokoff, Adrian A. Achuthan, Rodney B. Luwor
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3356 (2023)
Glioblastoma cells adapt to changes in glucose availability through metabolic plasticity allowing for cell survival and continued progression in low-glucose concentrations. However, the regulatory cytokine networks that govern the ability to survive
Externí odkaz:
https://doaj.org/article/746896258fcb47fa865cf5f0a4cfda65
Autor:
Clarissa A. Whitehead, Hong P.T. Nguyen, Andrew P. Morokoff, Rodney B. Luwor, Lucia Paradiso, Andrew H. Kaye, Theo Mantamadiotis, Stanley S. Stylli
Publikováno v:
Translational Oncology, Vol 11, Iss 6, Pp 1406-1418 (2018)
The most common primary central nervous system tumor in adults is the glioblastoma multiforme (GBM). The highly invasive nature of GBM cells is a significant factor resulting in the inevitable tumor recurrence and poor patient prognosis. Tumor cells
Externí odkaz:
https://doaj.org/article/f12dddd8362b479aa8ff965b8d2781c6
Autor:
Chenkai Ma, Hong P. T. Nguyen, Jordan J. Jones, Stanley S. Stylli, Clarissa A. Whitehead, Lucy Paradiso, Rodney B. Luwor, Zammam Areeb, Eric Hanssen, Ellie Cho, Ulrich Putz, Andrew H. Kaye, Andrew P. Morokoff
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2770 (2022)
Glioblastoma is the most aggressive brain tumour with short survival, partly due to resistance to conventional therapy. Glioma stem cells (GSC) are likely to be involved in treatment resistance, by releasing extracellular vesicles (EVs) containing sp
Externí odkaz:
https://doaj.org/article/7a906487ef7e4ed2a10e243bf2807fa1
Autor:
Juliana Gomez, Zammam Areeb, Sarah F. Stuart, Hong P. T. Nguyen, Lucia Paradiso, Ahmad Zulkifli, Sonakshi Madan, Vijay Rajagopal, Magdalene K. Montgomery, Hui K. Gan, Andrew M. Scott, Jordan Jones, Andrew H. Kaye, Andrew P. Morokoff, Rodney B. Luwor
Publikováno v:
Cancers, Vol 13, Iss 6, p 1198 (2021)
Reticulocalbin 1 (RCN1) is an endoplasmic reticulum (ER)-residing protein, involved in promoting cell survival during pathophysiological conditions that lead to ER stress. However, the key upstream receptor tyrosine kinase that regulates RCN1 express
Externí odkaz:
https://doaj.org/article/4e7ab66647e94fccb77f168917810ebd
Autor:
Marija Dinevska, Natalia Gazibegovic, Andrew P. Morokoff, Andrew H. Kaye, Katharine J. Drummond, Theo Mantamadiotis, Stanley S. Stylli
Publikováno v:
Cancers, Vol 12, Iss 10, p 2888 (2020)
Glioblastoma (GBM) is the most prevalent and malignant type of primary brain cancer. The rapid invasion and dissemination of tumor cells into the surrounding normal brain is a major driver of tumor recurrence, and long-term survival of GBM patients i
Externí odkaz:
https://doaj.org/article/0c98cb8acc0048d5a2c76e39ed08a7e5
Autor:
Dylan Jones, Clarissa A. Whitehead, Marija Dinevska, Samuel S. Widodo, Liam M. Furst, Andrew P. Morokoff, Andrew H. Kaye, Katharine J. Drummond, Theo Mantamadiotis, Stanley S. Stylli
Publikováno v:
Molecular and Cellular Biochemistry. 478:1251-1267
Glioblastoma (GBM) is the most prevalent primary central nervous system tumour in adults. The lethality of GBM lies in its highly invasive, infiltrative, and neurologically destructive nature resulting in treatment failure, tumour recurrence and deat
Autor:
Clarissa A. Whitehead, Haoyun Fang, Huaqi Su, Andrew P. Morokoff, Andrew H. Kaye, Eric Hanssen, Cameron J. Nowell, Katharine J. Drummond, David W. Greening, Laura J. Vella, Theo Mantamadiotis, Stanley S. Stylli
Publikováno v:
Cellular Oncology.
Purpose The therapeutic efficacy of radiotherapy/temozolomide treatment for glioblastoma (GBM) is limited by the augmented invasiveness mediated by invadopodia activity of surviving GBM cells. As yet, however the underlying mechanisms remain poorly u
Autor:
Benjamin Sinclair, Varduhi Cahill, Jarrel Seah, Andy Kitchen, Lucy E. Vivash, Zhibin Chen, Charles B. Malpas, Marie F. O'Shea, Patricia M. Desmond, Rodney J. Hicks, Andrew P. Morokoff, James A. King, Gavin C. Fabinyi, Andrew H. Kaye, Patrick Kwan, Samuel F. Berkovic, Meng Law, Terence J. O'Brien
Publikováno v:
Epilepsia. 63:1081-1092
Around 30% of patients undergoing surgical resection for drug-resistant mesial temporal lobe epilepsy (MTLE) do not obtain seizure freedom. Success of anterior temporal lobe resection (ATLR) critically depends on the careful selection of surgical can
Autor:
Paul M. Daniel, Frédéric Hollande, Andrew P. Morokoff, Gulay Filiz, Sebastian Dworkin, Theo Mantamadiotis, Daniel Brown, Wayne Ng, Nicole Kountouri, Stephanie Amiridis
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 2, p e0172791 (2017)
PLoS ONE, Vol 12, Iss 2, p e0172791 (2017)
Glioblastoma (GBM) is a heterogeneous tumor of the brain with a poor prognosis due to recurrence and drug resistance following therapy. Genome-wide profiling has revealed the existence of distinct GBM molecular subtypes that respond differently to ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b93541fc9763c8c99c234f613764a359