Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Andrew P. Joy"'
1
Akademický článek
A multiparametric extraction method for Vn96-isolated plasma extracellular vesicles and cell-free DNA that enables multi-omic profiling
Autor: Jeremy W. Roy, Catherine A. Taylor, Annie P. Beauregard, Surendar R. Dhadi, D. Craig Ayre, Sheena Fry, Simi Chacko, Gabriel Wajnberg, Andrew P. Joy, Ngoc-Nu Mai-Thi, Nicolas Crapoulet, David A. Barnett, Anirban Ghosh, Stephen M. Lewis, Rodney J. Ouellette
Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Extracellular vesicles (EVs) have been recognized as a rich material for the analysis of DNA, RNA, and protein biomarkers. A remaining challenge for the deployment of EV-based diagnostic and prognostic assays in liquid biopsy testing is the
Externí odkaz: https://doaj.org/article/e9305174dbe849828499522865518299
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2
Akademický článek
EBF1 drives hallmark B cell gene expression by enabling the interaction of PAX5 with the MLL H3K4 methyltransferase complex
Autor: Charles E. Bullerwell, Philippe Pierre Robichaud, Pierre M. L. Deprez, Andrew P. Joy, Gabriel Wajnberg, Darwin D’Souza, Simi Chacko, Sébastien Fournier, Nicolas Crapoulet, David A. Barnett, Stephen M. Lewis, Rodney J. Ouellette
Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract PAX5 and EBF1 work synergistically to regulate genes that are involved in B lymphocyte differentiation. We used the KIS-1 diffuse large B cell lymphoma cell line, which is reported to have elevated levels of PAX5 expression, to investigate t
Externí odkaz: https://doaj.org/article/5b11cbd215904b91952bccb6c01327a7
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3
Akademický článek
Decrease of Intracellular Glutamine by STF-62247 Results in the Accumulation of Lipid Droplets in von Hippel-Lindau Deficient Cells
Autor: Mathieu Johnson, Sarah Nowlan, Gülsüm Sahin, David A. Barnett, Andrew P. Joy, Mohamed Touaibia, Miroslava Cuperlovic-Culf, Daina Zofija Avizonis, Sandra Turcotte
Publikováno v: Frontiers in Oncology, Vol 12 (2022)
Kidney cancer is one of the top ten cancer diagnosed worldwide and its incidence has increased the last 20 years. Clear Cell Renal Cell Carcinoma (ccRCC) are characterized by mutations that inactivate the von Hippel-Lindau (VHL) tumor suppressor gene
Externí odkaz: https://doaj.org/article/5f3d652ddd3a49e68bd3850cf9d62e57
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4
Akademický článek
CD24 induces changes to the surface receptors of B cell microvesicles with variable effects on their RNA and protein cargo
Autor: D. Craig Ayre, Ian C. Chute, Andrew P. Joy, David A. Barnett, Andrew M. Hogan, Marc P. Grüll, Lourdes Peña-Castillo, Andrew S. Lang, Stephen M. Lewis, Sherri L. Christian
Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract The CD24 cell surface receptor promotes apoptosis in developing B cells, and we recently found that it induces B cells to release plasma membrane-derived, CD24-bearing microvesicles (MVs). Here we have performed a systematic characterization
Externí odkaz: https://doaj.org/article/5fdc4db9bd1d46f7b03db8910ae362c7
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5
Akademický článek
Proteome profiling of extracellular vesicles captured with the affinity peptide Vn96: comparison of Laemmli and TRIzol© protein-extraction methods
Autor: Andrew P. Joy, D. Craig Ayre, Ian C. Chute, Annie-Pier Beauregard, Gabriel Wajnberg, Anirban Ghosh, Stephen M. Lewis, Rodney J. Ouellette, David A. Barnett
Publikováno v: Journal of Extracellular Vesicles, Vol 7, Iss 1 (2018)
Sample amount is often a limiting factor for multi-parametric analyses that encompass at least three areas of ‘-omics’ research: genomics, transcriptomics and proteomics. Limited sample amounts are also an important consideration when these multi
Externí odkaz: https://doaj.org/article/02f0fbbf7e514b39abed339d6e78c9d3
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6
Akademický článek
Extraction, Antioxidant Capacity, 5-Lipoxygenase Inhibition, and Phytochemical Composition of Propolis from Eastern Canada
Autor: Mariama Sambou, Jacques Jean-François, Fanta J. Ndongou Moutombi, Jérémie A. Doiron, Mathieu P.A. Hébert, Andrew P. Joy, Ngoc-Nu Mai-Thi, David A. Barnett, Marc E. Surette, Luc H. Boudreau, Mohamed Touaibia
Publikováno v: Molecules, Vol 25, Iss 10, p 2397 (2020)
Soxhlet (SE), microwave-assisted (MAE) and ultrasound-assisted (UAE) extraction were compared using ten extraction solvents for their efficiency to extract phenolic and flavonoid antioxidants from Eastern Canada propolis. Extracts were compared for t
Externí odkaz: https://doaj.org/article/9b11f523997f4b50a231f04a57a84c20
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8
Decrease of Intracellular Glutamine by STF-62247 Results in the Accumulation of Lipid Droplets in von Hippel-Lindau Deficient Cells
Autor: Mathieu Johnson, Sarah Nowlan, Gülsüm Sahin, David A. Barnett, Andrew P. Joy, Mohamed Touaibia, Miroslava Cuperlovic-Culf, Daina Zofija Avizonis, Sandra Turcotte
Publikováno v: Frontiers in Oncology, Vol 12 (2022)
Kidney cancer is one of the top ten cancer diagnosed worldwide and its incidence has increased the last 20 years. Clear Cell Renal Cell Carcinoma (ccRCC) are characterized by mutations that inactivate the von Hippel-Lindau (VHL) tumor suppressor gene
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a324cf0afd3e6ab6ae2e2d897199c46
https://pubmed.ncbi.nlm.nih.gov/35223522
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9
Akademický článek
Quantitative and functional characterization of the hyper-conserved protein of Prochlorococcus and marine Synechococcus.
Autor: Caroline E Whidden, Katrina G DeZeeuw, Jackie K Zorz, Andrew P Joy, David A Barnett, Milo S Johnson, Olga Zhaxybayeva, Amanda M Cockshutt
Publikováno v: PLoS ONE, Vol 9, Iss 10, p e109327 (2014)
A large fraction of any bacterial genome consists of hypothetical protein-coding open reading frames (ORFs). While most of these ORFs are present only in one or a few sequenced genomes, a few are conserved, often across large phylogenetic distances.
Externí odkaz: https://doaj.org/article/323fa0ef58074df5ba54ddf6783e4c3c
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