Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Andrew P. Bluhm"'
Autor:
Michael H. Norris, Andrew P. Bluhm, Morgan C. Metrailer, Treenate Jiranantasak, Alexander Kirpich, Ted Hadfield, Jose Miguel Ponciano, Jason K. Blackburn
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract The Bacillus anthracis exosporium nap is the outermost portion of spore that interacts with the environment and host systems. Changes to this layer have the potential to impact wide-ranging physiological and immunological processes. The uniq
Externí odkaz:
https://doaj.org/article/f557ffbd5c7e4b17b41bf5e76739127a
Autor:
Marco Grodzki, Andrew P. Bluhm, Moritz Schaefer, Abderrahmane Tagmount, Max Russo, Amin Sobh, Roya Rafiee, Chris D. Vulpe, Stephanie M. Karst, Michael H. Norris
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-18 (2022)
Abstract Background The COVID-19 pandemic has resulted in 275 million infections and 5.4 million deaths as of December 2021. While effective vaccines are being administered globally, there is still a great need for antiviral therapies as antigenicall
Externí odkaz:
https://doaj.org/article/0389603ba2a943b3a03f0bb2d378231d
Autor:
Yun Heacock-Kang, Ian A. McMillan, Michael H. Norris, Zhenxin Sun, Jan Zarzycki-Siek, Andrew P. Bluhm, Darlene Cabanas, Robert E. Norton, Natkunam Ketheesan, Jeff F. Miller, Herbert P. Schweizer, Tung T. Hoang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Prokaryotic cell transcriptomics has been limited to mixed or sub-population dynamics and individual cells within heterogeneous populations. Here the authors develop a ‘TRANSITomic’ approach to profile transcriptomes of single Burkholderia pseudo
Externí odkaz:
https://doaj.org/article/7548060208f54f84aeb09a6fe6e50257
Autor:
Treenate Jiranantasak, Jamie S. Benn, Morgan C. Metrailer, Samantha J. Sawyer, Madison Q. Burns, Andrew P. Bluhm, Jason K. Blackburn, Michael H. Norris
Publikováno v:
PLoS ONE, Vol 17, Iss 9 (2022)
Anthrax is a zoonosis caused by the environmentally maintained, spore-forming bacterium Bacillus anthracis, affecting humans, livestock, and wildlife nearly worldwide. Bacterial spores are ingested, inhaled, and may be mechanically transmitted by bit
Externí odkaz:
https://doaj.org/article/ea885dc0c155491aa4de30844452e0b9
Autor:
John E. Ekakoro, Arnold Lubega, Edrine B. Kayaga, Dickson Ndoboli, Andrew P. Bluhm, Eddie M. Wampande, Jason K. Blackburn, Karyn A. Havas, Michael H. Norris
Publikováno v:
Pathogens, Vol 11, Iss 11, p 1363 (2022)
Burkholderia pseudomallei is a Gram-negative bacterium that causes melioidosis, a disease of humans and animals. It is primarily transmitted through direct contact with contaminated soil and surface water. The epidemiology of this pathogen in Africa,
Externí odkaz:
https://doaj.org/article/e15c6db5d395407a8a1e7a229dd7e4cd
Autor:
Yun Heacock-Kang, Ian A. McMillan, Jan Zarzycki-Siek, Zhenxin Sun, Andrew P. Bluhm, Darlene Cabanas, Tung T. Hoang
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Natural competency requires uptake of exogenous DNA from the environment and the integration of that DNA into recipient bacteria can be used for DNA-repair or genetic diversification. The Burkholderia genus is unique in that only some of the
Externí odkaz:
https://doaj.org/article/5a535abc1cd140ba895e895a2e73f401
Autor:
David A. Ostrov, Andrew P. Bluhm, Danmeng Li, Juveriya Qamar Khan, Megha Rohamare, Karthic Rajamanickam, Kalpana K. Bhanumathy, Jocelyne Lew, Darryl Falzarano, Franco J. Vizeacoumar, Joyce A. Wilson, Marco Mottinelli, Siva Rama Raju Kanumuri, Abhisheak Sharma, Christopher R. McCurdy, Michael H. Norris
Publikováno v:
Pathogens, Vol 10, Iss 11, p 1514 (2021)
(1) Background: There is a strong need for prevention and treatment strategies for COVID-19 that are not impacted by SARS-CoV-2 mutations emerging in variants of concern. After virus infection, host ER resident sigma receptors form direct interaction
Externí odkaz:
https://doaj.org/article/63add6fb9ba140d2866daea0ebf129c3
Autor:
John E, Ekakoro, Arnold, Lubega, Edrine B, Kayaga, Dickson, Ndoboli, Andrew P, Bluhm, Eddie M, Wampande, Jason K, Blackburn, Karyn A, Havas, Michael H, Norris
Publikováno v:
Pathogens (Basel, Switzerland). 11(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e58281390ae7a9831d1c35aad18428e6
https://pubmed.ncbi.nlm.nih.gov/36422614
https://pubmed.ncbi.nlm.nih.gov/36422614
Autor:
Michael H Norris, Yun Heacock-Kang, Jan Zarzycki-Siek, Andrew P Bluhm, Ian A McMillan, Herbert P Schweizer, Tung T Hoang
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189018 (2017)
Burkholderia spp. are genetically and physiologically diverse. Some strains are naturally transformable and capable of DNA catabolism. Burkholderia pseudomallei (Bp) strains 1026b and K96243 and B. thailandensis strain E264 are able to utilize DNA as
Externí odkaz:
https://doaj.org/article/9dadebfb7c7448368da264b1bd7e795f
Autor:
Michael H. Norris, Leah R. Reznikov, Danmeng Li, David A. Ostrov, Yan-Shin J. Liao, Atul J. Butte, Rohit Vashisht, Ashley N. Brown, Andrew P. Bluhm
Publikováno v:
Biochemical and Biophysical Research Communications
There is an urgent need to identify therapies that prevent SARS-CoV-2 infection and improve the outcome of COVID-19 patients. Although repurposed drugs with favorable safety profiles could have significant benefit, widely available prevention or trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf5bd2bcb2d6d3c725173b5e8beaddc
https://doi.org/10.1016/j.bbrc.2020.11.095
https://doi.org/10.1016/j.bbrc.2020.11.095