Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andrew P Cairns"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Targeted protein degradation (TPD) is a rapidly expanding field, with various PROTACs (proteolysis-targeting chimeras) in clinical trials and molecular glues such as immunomodulatory imide drugs (IMiDs) already well established in the treatment of ce
Externí odkaz:
https://doaj.org/article/e0ff70d75267414ca024682086e6d311
Autor:
Joseph A. M. Paddison, Georg Ehlers, Andrew B. Cairns, Jason S. Gardner, Oleg A. Petrenko, Nicholas P. Butch, Dmitry D. Khalyavin, Pascal Manuel, Henry E. Fischer, Haidong Zhou, Andrew L. Goodwin, J. Ross Stewart
Publikováno v:
npj Quantum Materials, Vol 6, Iss 1, Pp 1-8 (2021)
Abstract In partially ordered magnets, order and disorder coexist in the same magnetic phase, distinct from both spin liquids and spin solids. Here, we determine the nature of partial magnetic ordering in the canonical frustrated antiferromagnet Gd2T
Externí odkaz:
https://doaj.org/article/2969a7d067f84fd2bfbb90befc66c561
Autor:
Omer Ad, Kyle S. Hoffman, Andrew G. Cairns, Aaron L. Featherston, Scott J. Miller, Dieter Söll, Alanna Schepartz
Publikováno v:
ACS Central Science, Vol 5, Iss 7, Pp 1289-1294 (2019)
Externí odkaz:
https://doaj.org/article/faa14b0313454a72837f55c6e90d28b7
Autor:
Rachel Kelly, Andrew G. Cairns, Jörgen Ådén, Fredrik Almqvist, Alexis-Pierre Bemelmans, Emmanuel Brouillet, Tommy Patton, Declan P. McKernan, Eilís Dowd
Publikováno v:
Biomolecules, Vol 11, Iss 11, p 1685 (2021)
Animal models of Parkinson’s disease, in which the human α-synuclein transgene is overexpressed in the nigrostriatal pathway using viral vectors, are widely considered to be the most relevant models of the human condition. However, although highly
Externí odkaz:
https://doaj.org/article/c447a4e33b7344ddb7f816064af2a6e0
Autor:
Alistair R. Overy, Andrew B. Cairns, Matthew J. Cliffe, Arkadiy Simonov, Matthew G. Tucker, Andrew L. Goodwin
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Conventional crystallography focuses on structurally-ordered systems, where interesting physics or novel material functions emerge. Here, Overy et al. propose an approach of designing functional materials with strongly correlated disorder, which can
Externí odkaz:
https://doaj.org/article/d67c4dbaa68a433e8217dbf7f3282553
Autor:
Antony Nearchou, Mero-Lee U. Cornelius, Jonathan M. Skelton, Zöe L. Jones, Andrew B. Cairns, Ines E. Collings, Paul R. Raithby, Stephen A. Wells, Asel Sartbaeva
Publikováno v:
Molecules, Vol 24, Iss 3, p 641 (2019)
The roles of organic additives in the assembly and crystallisation of zeolites are still not fully understood. This is important when attempting to prepare novel frameworks to produce new zeolites. We consider 18-crown-6 ether (18C6) as an additive,
Externí odkaz:
https://doaj.org/article/a6ad80a4132f43729ed6617bbd1e5225
Autor:
Joe eGallagher, Andrew J Cairns, David eThomas, Emma eTimms-Taravella, Kirsten eSkot, Adam eChalton, Peter eWilliams, Lesley B Turner
Publikováno v:
Frontiers in Plant Science, Vol 6 (2015)
Differences have been shown between ryegrass and fescue within the Festulolium subline introgression family for fructan synthesis, metabolism and polymer-size traits. It is well-established that there is considerable variation for water-soluble carbo
Externí odkaz:
https://doaj.org/article/fda576dd9a6b4bac85260c91c1e30cd8
Autor:
Joe A Gallagher, Andrew J Cairns, David eThomas, Adam eCharlton, Peter eWilliams, Lesley B Turner
Publikováno v:
Frontiers in Plant Science, Vol 6 (2015)
The fructans found as storage carbohydrates in temperate forage grasses have a physiological role in regrowth and stress tolerance. They are also important for the nutritional value of fresh and preserved livestock feeds, and are potentially useful a
Externí odkaz:
https://doaj.org/article/a434319b6f0f48d589f6847a210a0892
Publikováno v:
Nephrology Dialysis Transplantation. 15:1232-1234
Publikováno v:
Annals of the Rheumatic Diseases. 64:338-339
Osteoporosis is a common feature of ankylosing spondylitis (AS), and vertebral fractures are an increasingly recognised complication. A cumulative fracture prevalence of between 9.5% and 18% has been reported, with a six- to eightfold relative increa