Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Andrew P, Kowalczyk"'
Autor:
Tadahiko Seo, Anthony M Lowery, Haifang Xu, William Giang, Sergey M Troyanovsky, Peter A Vincent, Andrew P Kowalczyk
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0290485 (2024)
Cadherin family proteins play a central role in epithelial and endothelial cell-cell adhesion. The dynamic regulation of cell adhesion is achieved in part through endocytic membrane trafficking pathways that modulate cadherin cell surface levels. Her
Externí odkaz:
https://doaj.org/article/b54ca59df666457a903728babb8e2202
Autor:
Yeon Ja Choi, Christine Laclef, Ning Yang, Abraham Andreu-Cervera, Joshua Lewis, Xuming Mao, Li Li, Elizabeth R Snedecor, Ken-Ichi Takemaru, Chuan Qin, Sylvie Schneider-Maunoury, Kenneth R Shroyer, Yusuf A Hannun, Peter J Koch, Richard A Clark, Aimee S Payne, Andrew P Kowalczyk, Jiang Chen
Publikováno v:
PLoS Genetics, Vol 15, Iss 1, p e1007914 (2019)
Cilia-related proteins are believed to be involved in a broad range of cellular processes. Retinitis pigmentosa GTPase regulator interacting protein 1-like (RPGRIP1L) is a ciliary protein required for ciliogenesis in many cell types, including epider
Externí odkaz:
https://doaj.org/article/91c59b0e21eb42e691e40426a8db2724
Autor:
Volker Spindler, Brenda Gerull, Kathleen J. Green, Andrew P. Kowalczyk, Rudolf Leube, Ali J. Marian, Hendrik Milting, Eliane J. Müller, Carien Niessen, Aimee S. Payne, Nicolas Schlegel, Enno Schmidt, Pavel Strnad, Ritva Tikkanen, Franziska Vielmuth, Jens Waschke
Publikováno v:
Journal of cell science. 136(1)
Desmosome diseases are caused by dysfunction of desmosomes, which anchor intermediate filaments (IFs) at sites of cell–cell adhesion. For many decades, the focus of attention has been on the role of actin filament-associated adherens junctions in d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e647fdef5b453b011c2912320c31d0
https://pubmed.ncbi.nlm.nih.gov/36594662
https://pubmed.ncbi.nlm.nih.gov/36594662
Autor:
Omer Shafraz, Matthias Rübsam, Sara N Stahley, Amber L Caldara, Andrew P Kowalczyk, Carien M Niessen, Sanjeevi Sivasankar
Publikováno v:
eLife, Vol 7 (2018)
Desmosomes are adhesive junctions composed of two desmosomal cadherins: desmocollin (Dsc) and desmoglein (Dsg). Previous studies demonstrate that E-cadherin (Ecad), an adhesive protein that interacts in both trans (between opposing cells) and cis (on
Externí odkaz:
https://doaj.org/article/5821de065c2f44f7a1df069725e9a5e5
Autor:
Sindora R. Baddam, Paul T. Arsenovic, Vani Narayanan, Nicole R. Duggan, Carl R. Mayer, Shaston T. Newman, Dahlia A. Abutaleb, Abhinav Mohan, Andrew P. Kowalczyk, Daniel E. Conway
Publikováno v:
Cells, Vol 7, Iss 7, p 66 (2018)
Cell-cell junctions are critical structures in a number of tissues for mechanically coupling cells together, cell-to-cell signaling, and establishing a barrier. In many tissues, desmosomes are an important component of cell-cell junctions. Loss or im
Externí odkaz:
https://doaj.org/article/b5a830ecd59548cfa00828a64ab02402
Autor:
Sara N Stahley, Masataka Saito, Victor Faundez, Michael Koval, Alexa L Mattheyses, Andrew P Kowalczyk
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87809 (2014)
Strong intercellular adhesion is critical for tissues that experience mechanical stress, such as the skin and heart. Desmosomes provide adhesive strength to tissues by anchoring desmosomal cadherins of neighboring cells to the intermediate filament c
Externí odkaz:
https://doaj.org/article/f26634a8dbb7446da5ecc252d87bcd06
Autor:
Andrew P. Kowalczyk, William F. Dean, Alexa L. Mattheyses, Tara M. Urner, Reena R. Beggs, Emily I. Bartle, Tejeshwar C. Rao
Publikováno v:
The Journal of Cell Biology
Desmosomes regulate intercellular adhesion, which controls tissue strength and plasticity. Bartle et al. show that desmosome adhesive strength is modulated through protein exchange in and out of desmosomes, not cadherin order. This exchange is tuned
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff31c5fdfed488317ce0c78abed053c
https://doi.org/10.1083/jcb.201906153
https://doi.org/10.1083/jcb.201906153
Publikováno v:
Biophysical Journal. 121:280a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::636a739a208e0658eae5fff68d5dcec9
https://doi.org/10.1016/j.bpj.2021.11.1360
https://doi.org/10.1016/j.bpj.2021.11.1360
Autor:
Masataka Saito, Sara N Stahley, Christopher Y Caughman, Xuming Mao, Dana K Tucker, Aimee S Payne, Masayuki Amagai, Andrew P Kowalczyk
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50696 (2012)
Pemphigus vulgaris (PV) is an autoimmune epidermal blistering disease caused by autoantibodies directed against the desmosomal cadherin desmoglein-3 (Dsg3). Significant advances in our understanding of pemphigus pathomechanisms have been derived from
Externí odkaz:
https://doaj.org/article/7d26637be73a43b3928bd2dfeb90b566
Autor:
Masayuki Amagai, Detlef Zillikens, Eliane J. Müller, Andrew P. Kowalczyk, Volker Spindler, Animesh A. Sinha, Enno Schmidt, Eli Sprecher, Michael Hertl, Jens Waschke, Sergei A. Grando, Marcel F. Jonkman, Carlo Pincelli, Rüdiger Eming, Aimee S. Payne
Publikováno v:
Journal of Investigative Dermatology. 138(1):32-37
The autoimmune blistering skin disease pemphigus is caused by IgG autoantibodies against desmosomal cadherins, but the precise mechanisms are in part a matter of controversial discussions. This review focuses on the currently existing models of the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07dc82e4da6e23e2ac2b59c0fdd4a6f7
https://hdl.handle.net/11370/da8c302a-6d4a-4ffb-9c4c-5ed02b19e548
https://hdl.handle.net/11370/da8c302a-6d4a-4ffb-9c4c-5ed02b19e548