Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Andrew P, Fellowes"'
Autor:
Christopher R McEvoy, Timothy Semple, Bhargavi Yellapu, David Y Choong, Huiling Xu, Gisela Mir Arnau, Andrew P Fellowes, Stephen B Fox
Publikováno v:
BioTechniques, Vol 68, Iss 1, Pp 48-51 (2020)
Tumor DNA sequencing results can have important clinical implications. However, its use is often limited by low DNA input, owing to small tumor biopsy size. To help overcome this limitation we have developed a simple improvement to a commonly used ne
Externí odkaz:
https://doaj.org/article/8d50b3db32cc400ea046aa1aabde26c5
Publikováno v:
Modern Pathology. 36:100049
Autor:
Christopher R, McEvoy, Damien, Kee, Owen W J, Prall, Timothy D, Clay, Clare, Scott, Anastasia, Backhouse, Stephen B, Fox, Andrew P, Fellowes, Huiling, Xu
Publikováno v:
JCO precision oncology. 3
Autor:
Angela, Mweempwa, Huiling, Xu, Joseph H A, Vissers, Richard W, Tothill, Andrew D, Pattison, Andrew P, Fellowes, David M, Thomas, Gary, Richardson, Rodney J, Hicks, Sean M, Grimmond, Stephen B, Fox, Stephen J, Luen, Jayesh, Desai, Benjamin J, Solomon
Publikováno v:
JCO precision oncology. 5
Autor:
John F. Markham, Andrew P. Fellowes, Thomas Green, Jose Luis Leal, Roxane Legaie, Darren Cullerne, Tessa Morris, Tom John, Ben Solomon, Stephen B. Fox
Targeted RNA sequencing (RNA-seq) from FFPE specimens is used clinically in cancer for its ability to estimate gene expression and to detect fusions. Using a cohort of NSCLC patients, we sought to determine whether targeted RNA-seq could be used to m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9451ba0c35c58ce26a0b1dcb8f0b1ca3
Autor:
Christopher R, McEvoy, Holly, Holliday, Niko, Thio, Catherine, Mitchell, David Y, Choong, Bhargavi, Yellapu, Hui San, Leong, Huiling, Xu, Stephen, Lade, Judy, Browning, Elena A, Takano, David J, Byrne, Anthony J, Gill, Cuong P, Duong, Jason, Li, Andrew P, Fellowes, Stephen B, Fox, Alexander, Swarbrick, Owen W J, Prall
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 101(1)
Most NUTM1-rearranged neoplasms (NRNs) have fusions between NUTM1 and BRD (bromodomain-containing) family members and are termed NUT carcinomas (NCs) because they show some squamous differentiation. However, some NRNs are associated with fusions betw
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1645:146-151
Sequencing of all three fibrinogen genes from an individual with hypofibrinogenaemia led to the identification of two new point mutations in the Bbeta gene. Family studies showed the mutations Bbeta255 Arg-->His (Fibrinogen Merivale) and Bbeta148 Lys
Publikováno v:
Blood. 95:1709-1713
We investigated the molecular basis of hypofibrinogenemia in a man with a normal thrombin clotting time. Protein analysis indicated equal plasma expression of 2 different Bbeta alleles, and DNA sequencing confirmed heterozygosity for a new Bbeta235 P
Publikováno v:
British Journal of Haematology. 101:24-31
Fibrinogen Banks Peninsula was identified in the mother of a patient referred for investigation following recurrent epistaxis. Coagulation tests revealed prolonged thrombin and reptilase times and a decreased functional fibrinogen level. Thrombin-cat
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1138:290-296
We have identified a new species of apolipoprotein (apo) B in an individual with heterozygous hypobetalipoproteinemia. The new apo B (apo B-32) is the result of a single point mutation (1450 Gln----Stop) in the apo B gene that prevents full length tr