Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Andrew Oliveira Silva"'
Autor:
Andrew Oliveira Silva, Thais Cardoso Bitencourt, Jose Eduardo Vargas, Lucas Rosa Fraga, Eduardo Filippi-Chiela
Publikováno v:
Genetics and Molecular Biology, Vol 47, Iss suppl 1 (2024)
Abstract Senescence is a cellular state in which the cell loses its proliferative capacity, often irreversibly. Physiologically, it occurs due to a limited capacity of cell division associated with telomere shortening, the so-called replicative senes
Externí odkaz:
https://doaj.org/article/7985ae2e4eee4ebc914be328d0a3b137
Autor:
Maiquidieli Dal Berto, Giovana Tavares dos Santos, Aniúsca Vieira dos Santos, Andrew Oliveira Silva, José Eduardo Vargas, Rafael José Vargas Alves, Fernanda Barbisan, Ivana Beatrice Mânica da Cruz, Claudia Giuliano Bica
Publikováno v:
Discover Oncology, Vol 12, Iss 1, Pp 1-19 (2021)
Abstract Tamoxifen (TMX) is used as adjuvant therapy for estrogen receptor-positive (ER+) breast cancer cases due to its affinity and inhibitory effects. However, about 30% of cases show drug resistance, resulting in recurrence and metastasis, the le
Externí odkaz:
https://doaj.org/article/d6512120cfa24b16ae327a65e57f2e4d
Autor:
Edina Poletto, Andrew Oliveira Silva, Ricardo Weinlich, Priscila Keiko Matsumoto Martin, Davi Coe Torres, Roberto Giugliani, Guilherme Baldo
Publikováno v:
Expert Opinion on Biological Therapy. 23:353-364
Autor:
Andrea Baldasso-Zanon, Andrew Oliveira Silva, Nayara Franco, Rafael Picon, Guido Lenz, Patrícia Luciana da Costa Lopez, Eduardo Filippi-Chiela
Colorectal cancer (CRC) is the third most common and deadliest cancers globally. The primary chemotherapy used for treating CRC is a co-treatment of 5-fluoruracil (5FU) and Oxaliplatin (OXA). In this study, we investigated the cellular mechanisms tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0c2cec588e3650c47531c044e383d0e
https://doi.org/10.21203/rs.3.rs-2975359/v1
https://doi.org/10.21203/rs.3.rs-2975359/v1
Autor:
Ivana Beatrice Mânica da Cruz, Andrew Oliveira Silva, Giovana Tavares dos Santos, José Eduardo Vargas, Claudia Giuliano Bica, Rafael José Vargas Alves, Maiquidieli Dal Berto, Aniúsca Vieira dos Santos, Fernanda Barbisan
Publikováno v:
Discover. Oncology
Discover Oncology, Vol 12, Iss 1, Pp 1-19 (2021)
Discover Oncology, Vol 12, Iss 1, Pp 1-19 (2021)
Tamoxifen (TMX) is used as adjuvant therapy for estrogen receptor-positive (ER+) breast cancer cases due to its affinity and inhibitory effects. However, about 30% of cases show drug resistance, resulting in recurrence and metastasis, the leading cau
Autor:
Giovana Ravizzoni Onzi, Julia C Marcolin, Karine R Begnini, Luiza C. Pereira, Guido Lenz, Julieti H Buss, Eloisa Dalsin, Carolina Nunes Santo, Daphne Torgo, Giovana B Mantovani, Juliano Luiz Faccioni, Sidia M. Callegari-Jacques, Álvaro Vigo, Luana S. Lenz, Jephesson A.F. Santos, Paula A Bracco, Maurício Tavares Tamborindeguy, Thayana Monteiro, Andrew Oliveira Silva
Publikováno v:
Cancer research. 81(4)
Several phenotypes that impact the capacity of cancer cells to survive and proliferate are dynamic. Here we used the number of cells in colonies as an assessment of fitness and devised a novel method called Dynamic Fitness Analysis (DynaFit) to measu
Autor:
Marilda da Cruz Fernandes, Márcia Rosângela Wink, Giselle de Souza Moraes, Fábio Klamt, Andrew Oliveira Silva
Publikováno v:
European journal of cell biology. 99(5)
Differently of two-dimensional cell culture, three-dimensional (3D) multicellular spheroid model allows cells to establish cell-cell/cell-matrix interactions over the entire cell surface, more closely mimicking tumor microenvironments and cellular su
Autor:
Augusto Valadão Junqueira, Gláucia Confortin, Franciele Cristina Kipper, André Luis Marc, Eliseu Paglioli Neto, Guido Lenz, Andrew Oliveira Silva
Publikováno v:
Investigational New Drugs. 36:323-331
Glioblastoma (GBM) is a very aggressive tumor that has not had substantial therapeutic improvement since the introduction of temozolomide (TMZ) in combination with radiotherapy. Combining TMZ with other chemotherapeutic agents is a strategy that coul
Autor:
Márcia Giovenardi, Silvana Almeida, Andrew Oliveira Silva, Marilene Porawski, Vanessa Bollis, Renata Padilha Guedes, Ana Carolina de Moura, Alethea Gatto Barschak, Vanessa Feistauer, Joana Fisch
Publikováno v:
Physiologybehavior. 204
Genetic and environmental factors related to maternal diet may predispose offspring to serious diseases. However, consequences of a maternal diet intervention during gestation and lactation, and its association with caloric restriction after weaning
Autor:
Patrícia Luciana da Costa Lopez, Guido Lenz, Emilly Schlee Villodre, Karina Bettega Felipe, Andrew Oliveira Silva
Publikováno v:
Tumor Biology. 37:13743-13749
Although cancer is a chronic disease, most of the in vitro experiments to assess the effectiveness of intervention are performed in hours or a few days. Moreover, none of the available methodologies to measure cell proliferation are adapted to provid