Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Andrew Nickel"'
Publikováno v:
Circulation. 142
Introduction: Transcatheter aortic valve replacement (TAVR) has surpassed surgical valve replacement for the management of severe aortic stenosis. High grade AV block is a well-described complication following TAVR. Prior models for predicting risk o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78f033e92d6f63ca28d13fbba2d641fa
https://doi.org/10.1161/circ.142.suppl_3.13505
https://doi.org/10.1161/circ.142.suppl_3.13505
Autor:
Katherine A. Grant-Young, Andrew Nickel, Rajesh Onkardas Bora, Prakash Anjanappa, Bender John A, Kevin Kish, Kap-Sun Yeung, Dawn D. Parker, Joseph Raybon, Mark R. Witmer, Karen Rigat, Matthew G. Soars, Steven Sheriff, Yue-Zhong Shu, Kenneth S. Santone, Prashantha Gunaga, Kyle Parcella, Nicholas A. Meanwell, Jay O. Knipe, Susan B. Roberts, Alicia Ng, Michael Sinz, Kathy Mosure, Ying-Kai Wang, Brett R. Beno, Mengping Liu, Elizabeth Colston, Dennis M. Grasela, John F. Kadow, Qi Gao, Min Gao, Umesh Hanumegowda, Roy Haskell, Julie A. Lemm, Xiaoliang Zhuo, Changhong Wan, Kumaravel Selvakumar
Publikováno v:
Journal of Medicinal Chemistry. 60:4369-4385
The hepatitis C virus (HCV) NS5B replicase is a prime target for the development of direct-acting antiviral drugs for the treatment of chronic HCV infection. Inspired by the overlay of bound structures of three structurally distinct NS5B palm site al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e500f8c2cd73d6873f1280c193d753
https://doi.org/10.1021/acs.jmedchem.7b00328
https://doi.org/10.1021/acs.jmedchem.7b00328
Publikováno v:
Journal of the American College of Cardiology. 75:528
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0237bf0ca4c7607106415e4306203f3a
https://doi.org/10.1016/s0735-1097(20)31155-4
https://doi.org/10.1016/s0735-1097(20)31155-4
Autor:
Andrew Nickel, Faisal M. Merchant, Angel R. Leon, Mikhael F. El-Chami, Nabil F. Saba, Akshar V. Patel
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The incidence of cancer treatment–induced arrhythmia ( CTIA ) associated with novel, targeted chemotherapeutic agents ( TCA s) has not been well described. Methods and Results We identified all patients treated at our institution from Ja
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fddc20315662d3829124c33fa85ef6f
https://doi.org/10.1161/jaha.118.010101
https://doi.org/10.1161/jaha.118.010101
Autor:
Zhong Yang, Jay O. Knipe, Susan B. Roberts, Yong Tu, Paul E. Morin, Ying-Kai Wang, John Wan, Andrew Nickel, Katharine A. Grant-Young, Piyasena Hewawasam, Sam T. Chao, Xiaoliang Zhuo, Bergstrom Carl P, Brett R. Beno, Qi Gao, Dianlin Xie, Chong-Hwan Chang, Dawn D. Parker, Mian Gao, Alicia Regueiro-Ren, Mengping Liu, Umesh Hanumegowda, Richard J. Colonno, Kathy Mosure, Nicholas A. Meanwell, Min Ding, Lenore A. Pelosi, John F. Kadow, Xiaofan Zheng, Steven Sheriff, Voss Stacey A, Alicia Ng, Kenneth S. Santone, Mark R. Witmer, Jung-Hui Sun, Robert G. Gentles, Bender John A, Min Gao, Yi Wang, Jeff Tredup, Daniel M. Camac, Scott W. Martin, Thomas W. Hudyma, Julie A. Lemm, Kap-Sun Yeung, Karen Rigat
Publikováno v:
Journal of Medicinal Chemistry. 57:1855-1879
Described herein are structure-activity relationship studies that resulted in the optimization of the activity of members of a class of cyclopropyl-fused indolobenzazepine HCV NS5B polymerase inhibitors. Subsequent iterations of analogue design and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bef74807d123b8140c1724c36314db30
https://doi.org/10.1021/jm4016894
https://doi.org/10.1021/jm4016894
Autor:
Nicholas A. Meanwell, Brett R. Beno, John F. Kadow, Andrew Nickel, Susan B. Roberts, Steven Sheriff, Kyle Parcella, Changhong Wan, Ying-Kai Wang
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(2)
Alkoxyanthranilic acid derivatives have been identified to inhibit HCV NS5B polymerase, binding in an allosteric site located at the convergence of the palm and thumb regions. Information from co-crystal structures guided the structural design strate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d64a35dc5186a2ed177454a25ff779
https://pubmed.ncbi.nlm.nih.gov/27908764
https://pubmed.ncbi.nlm.nih.gov/27908764
Autor:
Andrew Nickel, Richard L. Pederson, Arthur A. Mallari, Yann Schrodi, Choon Woo Lee, Jason Papazian, Garik Mkrtumyan, Diana Stoianova, Jane Uy, Thay Ung, Wen-Hao Wei
Publikováno v:
Topics in Catalysis. 55:518-523
Recently, considerable attention has been focused on the use of olefin metathesis to convert oleochemicals into value-added products such as the bifunctional molecule methyl 9-decenoate, but the implementation of this process has been hampered by low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e5975657fcf156c1b2f3a2cf603b946
https://doi.org/10.1007/s11244-012-9830-2
https://doi.org/10.1007/s11244-012-9830-2
Publikováno v:
Journal of the American College of Cardiology. 71:A273
The incidence of cancer treatment-induced arrhythmia (CTIA) associated with novel, targeted chemotherapeutic agents (TCAs) has not been well described. We retrospectively identified all patients treated at our institution from January 2010 to Decembe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f23cb735dc7257e11a6b52e29b72d84
https://doi.org/10.1016/s0735-1097(18)30814-3
https://doi.org/10.1016/s0735-1097(18)30814-3
Publikováno v:
Proceedings of the Human Factors and Ergonomics Society Annual Meeting. 47:1122-1125
Three strategies for the trackball control of an end effector on a laparoscopic graspers tool were tested to see which strategy was most intuitive to the user. The three strategies (UURR, UDRL, UDRR) were tested on four different orientations of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1907a804a783792d3c58e789df179b84
https://doi.org/10.1177/154193120304701004
https://doi.org/10.1177/154193120304701004
Autor:
Andrew Nickel, Richard L. Pederson
Publikováno v:
Olefin Metathesis: Theory and Practice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b216f3d468104bc6193aa8a8d8de5207
https://doi.org/10.1002/9781118711613.ch11
https://doi.org/10.1002/9781118711613.ch11
