Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Andrew Neil James Mckenzie"'
Autor:
Tianxiao Liu, Zhaojie Meng, Jing Liu, Jie Li, Yuanyuan Zhang, Zhiyong Deng, Songyuan Luo, Minjie Wang, Qin Huang, Shuya Zhang, Pauline Fendt, Julie Devouassoux, Dazhu Li, Andrew Neil James McKenzie, Matthias Nahrendorf, Peter Libby, Junli Guo, Guo-Ping Shi
Publikováno v:
Cardiovascular Research. 119:1046-1061
Aims Group 2 innate lymphoid cells (ILC2s) regulate adaptive and innate immunities. In mouse heart, production of myocardial infarction (MI) increased ILC2 accumulation, suggesting a role for ILC2 in cardiac dysfunction post-MI. Methods and results W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8fcedecb9c7ae3eb979167d22a48444
https://doi.org/10.1093/cvr/cvac144
https://doi.org/10.1093/cvr/cvac144
Autor:
John T. Woosley, Warren D. Shlomchik, Trisha A. Dant, Shannon Reisdorf, Andrew Neil James Mckenzie, Karen P. McKinnon, Jenny P.-Y. Ting, David A. Serody, Danny W. Bruce, Heather E. Stefanski, Dietmar M. W. Zaiss, Bruce R. Blazar, James M. Coghill, Justin E. Wilson, Jonathan S. Serody, Paul M. Armistead, Hemamalini Bommiasamy, Benjamin G. Vincent
Acute graft-versus-host disease (aGVHD) is the most common complication for patients undergoing allogeneic stem cell transplantation. Despite extremely aggressive therapy targeting donor T cells, patients with grade III or greater aGVHD of the lower
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4385fdaa1f7b033f47a5862085777762
Autor:
Donal O'Shea, Roger J. S. Preston, Andrew E. Hogan, Andrew Neil James Mckenzie, Emily Hams, Felicity A. Wurlod, Hans Reimer Rodewald, Rachel Bermingham, Padraic G. Fallon
Publikováno v:
The FASEB Journal
Induction of a type 2 cellular response in the white adipose tissue leads to weight loss and improves glucose homeostasis in obese animals. Injection of obese mice with recombinant helminth-derived Schistosoma mansoni egg-derived ω1 (ω1), a potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4835987ed3fce1176edd76fff0d2dc7
http://mural.maynoothuniversity.ie/12402/
http://mural.maynoothuniversity.ie/12402/
Autor:
Hye Young Kim, Andrew Neil James Mckenzie, Dirk E. Smith, Dale T. Umetsu, Rosemarie H. DeKruyff, Nicole Baumgarth, Lee A. Albacker, Ya-Jen Chang
Publikováno v:
Nature Immunology. 12:631-638
Patients with asthma, a major public health problem, are at high risk for serious disease from influenza virus infection, but the pathogenic mechanisms by which influenza A causes airway disease and asthma are not fully known. We show here in a mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10e47c19855016d8aff34183d67d74f
https://doi.org/10.1038/ni.2045
https://doi.org/10.1038/ni.2045
Autor:
Waldiceu A. Verri, Fabiane Sônego, Foo Y. Liew, José C. Alves-Filho, Damo Xu, Maria Auxiliadora-Martins, Andrew Neil James Mckenzie, Fabricio O. Souto, Anibal Basile-Filho, Fernando Q. Cunha, Andressa de Freitas
Publikováno v:
Nature Medicine. 16:708-712
Sepsis is a systemic inflammatory condition following bacterial infection with a high mortality rate and limited therapeutic options. Here we show that interleukin-33 (IL-33) reduces mortality in mice with experimental sepsis from cecal ligation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c473c80f6afea1a650c48e6054a2232d
https://doi.org/10.1038/nm.2156
https://doi.org/10.1038/nm.2156
Autor:
Masato Kubo, Hisamichi Aizawa, Yoichi Nakanishi, Hiromasa Inoue, Takafumi Matsumoto, Brian G. Oliver, Kentaro Tanaka, Akihiko Yoshimura, Hiroyuki Tanaka, Tomoaki Hoshino, Janette K. Burgess, Atsushi Moriwaki, Judith L. Black, Koichiro Matsumoto, Satoru Fukuyama, Takako Nakano, Andrew Neil James Mckenzie
Publikováno v:
American Journal of Respiratory and Critical Care Medicine, 179(11), 992-998. AMER THORACIC SOC
RATIONALE: Th2 cytokines play an important role in allergic diseases. These cytokines activate signal transduction pathways, including Janus kinase/signal transducer and activator of transcription (STAT) signaling. Although the suppressor of cytokine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b583907d0315f2120c04f3582580a494
https://doi.org/10.1164/rccm.200806-992oc
https://doi.org/10.1164/rccm.200806-992oc
Autor:
Luke J. Higgins, Eric R. Schreiter, Shoji Sanada, Richard T. Lee, Andrew Neil James Mckenzie, Daihiko Hakuno
Publikováno v:
Journal of Clinical Investigation. 117:1538-1549
ST2 is an IL-1 receptor family member with transmembrane (ST2L) and soluble (sST2) isoforms. sST2 is a mechanically induced cardiomyocyte protein, and serum sST2 levels predict outcome in patients with acute myocardial infarction or chronic heart fai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e524421f875b58ffb426a9d0a9baabdb
https://doi.org/10.1172/jci30634
https://doi.org/10.1172/jci30634
Autor:
Kaushik Parthasarathi, Kesha Robinson, Debra D. Donaldson, Gabriele Grunig, Viswanath P. Kurup, Andrew Neil James Mckenzie, Eleen Daley, Anthony Chow, Thomas Tschernig, Jocelyn Padilla
Publikováno v:
The Journal of Immunology. 174:8097-8105
The large inhibitory effect of IL-13 blockers on the asthma phenotype prompted us to ask whether IL-13 would play a role in regulating the allergic immune response in addition to its documented effects on structural pulmonary cells. Because IL-13 doe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69149fdbcecd40aadce0586e29aaca62
https://doi.org/10.4049/jimmunol.174.12.8097
https://doi.org/10.4049/jimmunol.174.12.8097
Autor:
Chih-Hao Lee, Ling Qi, David Jacobi, Lingling Dai, Hang Shi, Karen Inouye, Sihao Liu, Kristopher J. Stanya, Joseph P. Mizgerd, Matthew R. Gangl, Yewei Ji, Jillian Barlow, Prerna Bhargava, Andrew Neil James Mckenzie
Hyperglycemia is a result of impaired insulin action on glucose production and disposal, and a major target of antidiabetic therapies. The study of insulin-independent regulatory mechanisms of glucose metabolism may identify new strategies to lower b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d87eda614c59d9475edc84da66479810
https://europepmc.org/articles/PMC3533296/
https://europepmc.org/articles/PMC3533296/
Autor:
Zhou Zhu, Tao Zheng, Sun Young Oh, Lauren Cohn, Yoon Keun Kim, Andrew Neil James Mckenzie, Robert J. Homer
Asthma is a chronic inflammatory disorder of the airways. Type 2 T helper (Th) cell-dominated inflammation in the lung is a hallmark of asthma. Src homology 2 domain-containing protein tyrosine phosphatase (SHP)-1 is a negative regulator in the signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d94f3fd4da8d705cf54bc5ea42dc819
https://europepmc.org/articles/PMC2677436/
https://europepmc.org/articles/PMC2677436/