Výsledky vyhledávání - "Andrew Needles"

Quantification of Endothelial αvβ3 Expression with High-Frequency Ultrasound and Targeted Microbubbles: In Vitro and In Vivo Studies

Autor: Andrew Needles, Thomas L. Theelen, Katja Steiger, Ilya Skachkov, Ben J. A. Janssen, Klazina Kooiman, Antonius F.W. van der Steen, Johan G. Bosch, Nico de Jong, Mat J.A.P. Daemen, Verya Daeichin, Judith C. Sluimer

Publikováno v: Ultrasound in Medicine and Biology, 42(9), 2283-2293. Elsevier Inc.
Ultrasound in medicine & biology, 42(9), 2283-2293. Elsevier USA
Ultrasound in Medicine and Biology, 42(9), 2283-2293. Elsevier Science

Angiogenesis is a critical feature of plaque development in atherosclerosis and might play a key role in both the initiation and later rupture of plaques. The precursory molecular or cellular pro-angiogenic events that initiate plaque growth and that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d702639bbc57f87e5fbd5d99a91b54e
https://doi.org/10.1016/j.ultrasmedbio.2016.05.005

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Quantification of bound microbubbles in ultrasound molecular imaging

Autor: Ilya Skachkov, Andrew Needles, Antonius F.W. van der Steen, Verya Daeichin, Klazina Kooiman, Johan G. Bosch, Judith C. Sluimer, Ben J. A. Janssen, Zeynettin Akkus, Nico de Jong, Mat J.A.P. Daemen

Publikováno v: Ieee Transactions on Ultrasonics Ferroelectrics and Frequency Control, 62(6), 1190-1200. IEEE
IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 62(6), 1190-1200. Institute of Electrical and Electronics Engineers Inc.
IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control, 62(6), 1190-1200. Institute of Electrical and Electronics Engineers Inc.

Molecular markers associated with diseases can be visualized and quantified noninvasively with targeted ultrasound contrast agent (t-UCA) consisting of microbubbles (MBs) that can bind to specific molecular targets. Techniques used for quantifying t-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9048e69c5c3a7ae211624f062fd1ba66
https://doi.org/10.1109/tuffc.2015.006264

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Subharmonic, non-linear fundamental and ultraharmonic imaging of microbubble contrast at high frequencies

Autor: F. Stuart Foster, Verya Daeichin, Johan G. Bosch, Nico de Jong, Andrew Needles, Antonius F.W. van der Steen

Publikováno v: Ultrasound in Medicine and Biology, 41(2), 486-497. Elsevier Inc.

There is increasing use of ultrasound contrast agent in high-frequency ultrasound imaging. However, conventional contrast detection methods perform poorly at high frequencies. We performed systematic in vitro comparisons of subharmonic, non-linear fu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7a0758df5d6dfa1e6ffbe1f553952c3
https://hdl.handle.net/1765/84718

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Ultrasound

Autor: Stuart Foster, J. M. Hyvelin, Minalini Lakshman, Andrew Needles, I. Tardy, François Tranquart

Publikováno v: Small Animal Imaging ISBN: 9783319422008

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f3a01f7456b5f93bb7b5a5c1025b032
https://doi.org/10.1007/978-3-319-42202-2_14

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Screening and quantification of the tumor microenvironment with micro-ultrasound and photoacoustic imaging

Autor: Andrew Needles, Minalini Lakshman

Publikováno v: Nature Methods. 12:iii-v

The family of Vevo® Imaging Systems from FUJIFILM VisualSonics, Inc. is leading to translational breakthroughs in the understanding of cancer progression and therapy. More specifically, high-frequency ultrasound and photoacoustic imaging of orthotop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::768ef3c7120bee13056d49facd066090
https://doi.org/10.1038/nmeth.f.381

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Development and initial application of a fully integrated photoacoustic micro-ultrasound system

Autor: A. Heinmiller, Desmond Hirson, J. Sun, D. Bates, Melissa Yin, Andrew Needles, F.S. Foster, C. Theodoropoulos

Publikováno v: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 60:888-897

Photoacoustic (PA) imaging for biomedical applications has been under development for many years. Based on the many advances over the past decade, a new photoacoustic imaging system has been integrated into a micro-ultrasound platform for co-register

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4adf0f5b80ea2911c36a44b7379be73
https://doi.org/10.1109/tuffc.2013.2646

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Novel Single-Chain Antibody-Targeted Microbubbles for Molecular Ultrasound Imaging of Thrombosis

Autor: Ingo Ahrens, Christoph E. Hagemeyer, Manfred Olschewski, Karlheinz Peter, Ephraem Leitner, Xiaowei Wang, Fu Jia, Andrew Needles, Paul C Armstrong, Jan David Hohmann

Publikováno v: Circulation. 125:3117-3126

Background— Molecular imaging is a fast emerging technology allowing noninvasive detection of vascular pathologies. However, imaging modalities offering high resolution currently do not allow real-time imaging. We hypothesized that contrast-enhance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8cc82e17d1898495c489f9e722baa4f6
https://doi.org/10.1161/circulationaha.111.030312

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A New 15–50 MHz Array-Based Micro-Ultrasound Scanner for Preclinical Imaging

Autor: F. Stuart Foster, Chris Chaggares, Desmond Hirson, Andrew Needles, James Mehi, Christopher J. White, Marc Lukacs

Publikováno v: Ultrasound in Medicine & Biology. 35:1700-1708

Most institutions now have a suite of imaging tools to follow mouse models of human disease. Micro-ultrasound is one of these tools and is second after whole-mouse fluorescence or bioluminescent imaging, in terms of installed systems. We report in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e65bec8a8691101f0b218a3c0008f52
https://doi.org/10.1016/j.ultrasmedbio.2009.04.012

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High-Frequency Subharmonic Pulsed-Wave Doppler and Color Flow Imaging of Microbubble Contrast Agents

Autor: Emmanuel Cherin, David E. Goertz, F.S. Foster, Allison S. Brown, Raffi Karshafian, Andrew Needles, Peter N. Burns

Publikováno v: Ultrasound in Medicine & Biology. 34:1139-1151

A recent study has shown the feasibility of subharmonic (SH) flow imaging at a transmit frequency of 20 MHz. This paper builds on these results by examining the performance of SH flow imaging as a function of transmit pressure. Further, we also inves

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c990339820fbb6f9d8b15fd6a49ac29
https://doi.org/10.1016/j.ultrasmedbio.2007.12.011

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Noninvasive Ultrasonic Measurement of Regional and Local Pulse-Wave Velocity in Mice

Autor: F. Stuart Foster, Yu-Qing Zhou, Andrew Needles, Ross Williams, R. Mark Henkelman, S. Lee Adamson, Emmanuel Cherin

Publikováno v: Ultrasound in Medicine & Biology. 33:1368-1375

Mouse models of human disease are increasingly used to study the nature of cardiovascular diseases such as atherosclerosis. The pulse wave velocity (PWV) provides an indirect measure of arterial stiffness and can be useful for characterizing disease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e9fbd9170634551cd77dfcfe85bf05
https://doi.org/10.1016/j.ultrasmedbio.2007.03.012

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