Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Andrew N. Tutt"'
Autor:
Ricarda M. Hoffmann, Ben G. T. Coumbe, Debra H. Josephs, Silvia Mele, Kristina M. Ilieva, Anthony Cheung, Andrew N. Tutt, James F. Spicer, David E. Thurston, Silvia Crescioli, Sophia N. Karagiannis
Publikováno v:
OncoImmunology, Vol 7, Iss 3 (2018)
Antibody-drug conjugates (ADCs) are emerging as effective tools in cancer therapy, combining the antibody's exquisite specificity for the target antigen-expressing cancer cell together with the cytotoxic potency of the payload. Much success stems fro
Externí odkaz:
https://doaj.org/article/5d2494482e864414bfd81f737138fa2c
Autor:
Kristina M. Ilieva, Judit Fazekas-Singer, Daniela Y. Achkova, Tihomir S. Dodev, Silvia Mele, Silvia Crescioli, Heather J. Bax, Anthony Cheung, Panagiotis Karagiannis, Isabel Correa, Mariangela Figini, Rebecca Marlow, Debra H. Josephs, Andrew J. Beavil, John Maher, James F. Spicer, Erika Jensen-Jarolim, Andrew N. Tutt, Sophia N. Karagiannis
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Monoclonal antibodies find broad application as therapy for various types of cancer by employing multiple mechanisms of action against tumors. Manipulating the Fc-mediated functions of antibodies that engage immune effector cells, such as NK cells, r
Externí odkaz:
https://doaj.org/article/bfbb7f2ff9a14713b7358d8a541f67b6
Autor:
Jonathan D.H. Morris, Andrew N. Tutt, Spiros Linardopoulos, Charles M. Marson, Ignatius A. Tavares, Yolanda Olmos, Marta Reyes-Corral, Caterina Giacomini, Chuay-Yeng Koo
Live images of growing MCF-10A cells treated with compound 43. Representative time-lapse video images showing GFP-α-tubulin expressing MCF10-A cells incubated in growth medium containing compound 43 (5 µM) for 48 hours.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::343cfa7530118221e29d23305a4f8bb8
https://doi.org/10.1158/1535-7163.22509819
https://doi.org/10.1158/1535-7163.22509819
Autor:
Jonathan D.H. Morris, Andrew N. Tutt, Spiros Linardopoulos, Charles M. Marson, Ignatius A. Tavares, Yolanda Olmos, Marta Reyes-Corral, Caterina Giacomini, Chuay-Yeng Koo
Supplementary Materials, Methods and Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f15aa36242e06bbd6ad39b8d1bacb25
https://doi.org/10.1158/1535-7163.22509825
https://doi.org/10.1158/1535-7163.22509825
Autor:
Jonathan D.H. Morris, Andrew N. Tutt, Spiros Linardopoulos, Charles M. Marson, Ignatius A. Tavares, Yolanda Olmos, Marta Reyes-Corral, Caterina Giacomini, Chuay-Yeng Koo
Profile showing the activity of 70 different kinases in the presence of TAOK inhibitor compounds. In vitro kinase assays were carried out incubating kinases with or without compound 43 or 63 (0.3 µM) as indicated. Changes in the phosphorylation of M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d81a71feb9317bfb0f52f38e26a7bf1
https://doi.org/10.1158/1535-7163.22509810
https://doi.org/10.1158/1535-7163.22509810
Autor:
Rachael Natrajan, Andrew N. Tutt, Syed Haider, Jyoti S. Choudhary, Fredrik Wallberg, Frances Daley, Paul Huang, Lukas Krasny, Simon McDade, Gerard Quinn, Sophie Postel-Vinay, Farzana Noor, Maggie C.U. Cheang, Erle M. Holgersen, Lesley-Ann Martin, Sunil Pancholi, Ioannis Roxanis, Patrycja Gazinska, Kalnisha Naidoo, Natasa Medic Milijic, Snezana Susnjar, Daniela Kolarevic, Naomi Guppy, Eleanor Knight, Daniela Novo, Rebecca Marlow, Richard Buus, Gillian Farnie, Keith Brennan, Giulia Falgari, Amy Gibson, Lu Yu, Divya Kriplani, Eamonn Morrison, Holly E. Barker, Sarah L. Maguire, Patty T. Wai, Hannah Cottom, Gareth Muirhead, Ioanna Mavrommati, Philip Bland, Barrie Peck
Enrichment analysis from TCGA RNA-seq and RPPA data comparing CREBBPaltered versus wild-type patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273510b1dd0d539ca6c9b1f08a4eff95
https://doi.org/10.1158/0008-5472.22426827
https://doi.org/10.1158/0008-5472.22426827
Autor:
Rachael Natrajan, Andrew N. Tutt, Syed Haider, Jyoti S. Choudhary, Fredrik Wallberg, Frances Daley, Paul Huang, Lukas Krasny, Simon McDade, Gerard Quinn, Sophie Postel-Vinay, Farzana Noor, Maggie C.U. Cheang, Erle M. Holgersen, Lesley-Ann Martin, Sunil Pancholi, Ioannis Roxanis, Patrycja Gazinska, Kalnisha Naidoo, Natasa Medic Milijic, Snezana Susnjar, Daniela Kolarevic, Naomi Guppy, Eleanor Knight, Daniela Novo, Rebecca Marlow, Richard Buus, Gillian Farnie, Keith Brennan, Giulia Falgari, Amy Gibson, Lu Yu, Divya Kriplani, Eamonn Morrison, Holly E. Barker, Sarah L. Maguire, Patty T. Wai, Hannah Cottom, Gareth Muirhead, Ioanna Mavrommati, Philip Bland, Barrie Peck
Supplementary Figures and legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30c794ec4e55abe3f4a584efaba6af9c
https://doi.org/10.1158/0008-5472.22426848
https://doi.org/10.1158/0008-5472.22426848
Autor:
Rachael Natrajan, Andrew N. Tutt, Syed Haider, Jyoti S. Choudhary, Fredrik Wallberg, Frances Daley, Paul Huang, Lukas Krasny, Simon McDade, Gerard Quinn, Sophie Postel-Vinay, Farzana Noor, Maggie C.U. Cheang, Erle M. Holgersen, Lesley-Ann Martin, Sunil Pancholi, Ioannis Roxanis, Patrycja Gazinska, Kalnisha Naidoo, Natasa Medic Milijic, Snezana Susnjar, Daniela Kolarevic, Naomi Guppy, Eleanor Knight, Daniela Novo, Rebecca Marlow, Richard Buus, Gillian Farnie, Keith Brennan, Giulia Falgari, Amy Gibson, Lu Yu, Divya Kriplani, Eamonn Morrison, Holly E. Barker, Sarah L. Maguire, Patty T. Wai, Hannah Cottom, Gareth Muirhead, Ioanna Mavrommati, Philip Bland, Barrie Peck
Triple-negative breast cancers (TNBC) are resistant to standard-of-care chemotherapy and lack known targetable driver gene alterations. Identification of novel drivers could aid the discovery of new treatment strategies for this hard-to-treat patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f47c62b476b5b1eb748b5362d5aeca
https://doi.org/10.1158/0008-5472.c.6512466.v1
https://doi.org/10.1158/0008-5472.c.6512466.v1
Autor:
Rachael Natrajan, Andrew N. Tutt, Syed Haider, Jyoti S. Choudhary, Fredrik Wallberg, Frances Daley, Paul Huang, Lukas Krasny, Simon McDade, Gerard Quinn, Sophie Postel-Vinay, Farzana Noor, Maggie C.U. Cheang, Erle M. Holgersen, Lesley-Ann Martin, Sunil Pancholi, Ioannis Roxanis, Patrycja Gazinska, Kalnisha Naidoo, Natasa Medic Milijic, Snezana Susnjar, Daniela Kolarevic, Naomi Guppy, Eleanor Knight, Daniela Novo, Rebecca Marlow, Richard Buus, Gillian Farnie, Keith Brennan, Giulia Falgari, Amy Gibson, Lu Yu, Divya Kriplani, Eamonn Morrison, Holly E. Barker, Sarah L. Maguire, Patty T. Wai, Hannah Cottom, Gareth Muirhead, Ioanna Mavrommati, Philip Bland, Barrie Peck
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c4effcc5998d9f682e738dbf181bdc
https://doi.org/10.1158/0008-5472.22426845
https://doi.org/10.1158/0008-5472.22426845
Autor:
Alan Ashworth, Graeme C.M. Smith, Małgorzata Z. Zdzienicka, Andrew N. Tutt, Mark J. O'Connor, Sabrina Giavara, Sally Swift, Aneta Białkowska, Katarzyna Kluzek, Christopher J. Lord, Nicholas C. Turner, Nuala McCabe
Supplementary Tables S1 & S2 and Figures S1a & S1b from Deficiency in the Repair of DNA Damage by Homologous Recombination and Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0275023ac8fe0956ac3319d08ea1d67d
https://doi.org/10.1158/0008-5472.22365228
https://doi.org/10.1158/0008-5472.22365228