Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Andrew N. Krutchinsky"'
Autor:
Chao-yuh Yang, Jin Wang, Andrew N. Krutchinsky, Brian T. Chait, Joel D. Morrisett, Charles V. Smith
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 11, Pp 1891-1896 (2001)
In contrast to the multiple low abundance 2,4-dinitrophenylhydrazine-reactive tryptic peptides formed by oxidation of LDL with reagent HOCl in vitro, myeloperoxidase-catalyzed oxidation produces a dominant product in considerably greater yield and se
Externí odkaz:
https://doaj.org/article/b5ab23b6e9a947df8b201764a4720650
Publikováno v:
PLoS ONE, Vol 2, Iss 4, p e358 (2007)
The combination of high accuracy, sensitivity and speed of single and multiple-stage mass spectrometric analyses enables the collection of comprehensive sets of data containing detailed information about complex biological samples. To achieve these p
Externí odkaz:
https://doaj.org/article/271aa4b634654d9990d2f4d68cc69b10
Publikováno v:
Journal of the American Society for Mass Spectrometry. 26:659-667
We demonstrate that the efficiency of ion transmission from atmosphere to vacuum through stainless steel electrodes that contain slowly divergent conical duct (ConDuct) channels can be close to 100%. Here, we explore the properties of 2.5-cm-long ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c8ddd8310babe0407d737b600871de
https://doi.org/10.1007/s13361-014-1063-0
https://doi.org/10.1007/s13361-014-1063-0
Autor:
Raul Andino, Bassam Berry, Michel Tassetto, John D. Gross, Andrew N. Krutchinsky, Changhui Deng, Ashley Acevedo, Arabinda Nayak, Mark Kunitomi, Christophe Antoniewski
Publikováno v:
Nature structural & molecular biology
Nature structural & molecular biology, vol 17, iss 5
Nature structural & molecular biology, vol 17, iss 5
Insect viruses have evolved strategies to control the host RNAi antiviral defense mechanism. In nature, Drosophila melanogaster C virus (DCV) infection causes low mortality and persistent infection, whereas the closely related cricket paralysis virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83579797653cd92bfec159a3336494ca
http://europepmc.org/articles/PMC3815677
http://europepmc.org/articles/PMC3815677
Autor:
Poulomi Acharya, Changhui Deng, Nicholas Hoe, Andrew N. Krutchinsky, YongQiang Wang, Maria Almira Correia, Mingxiang Liao
Publikováno v:
Journal of Biological Chemistry. 284:5671-5684
Cytochromes P450 (P450s) incur phosphorylation. Although the precise role of this post-translational modification is unclear, marking P450s for degradation is plausible. Indeed, we have found that after structural inactivation, CYP3A4, the major huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5646fe64738b39f4ea4ba88ff8d78ed
https://doi.org/10.1074/jbc.m806104200
https://doi.org/10.1074/jbc.m806104200
Autor:
Cristina Ghenoiu, Eileen M. Woo, Hironori Funabiki, Lisa Postow, Andrew N. Krutchinsky, Brian T. Chait
Publikováno v:
The Journal of Cell Biology
The Ku70/Ku80 heterodimer, or Ku, is the central component of the nonhomologous end joining (NHEJ) pathway of double strand break (DSB) repair. Because Ku forms a ring through which the DSB threads, it likely becomes topologically attached to DNA dur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d46fbdb7c24159bd71e9ce754049ef
https://doi.org/10.1083/jcb.200802146
https://doi.org/10.1083/jcb.200802146
Publikováno v:
Nature. 454:353-357
The cell cycle couples growth and cell division to ensure the consistent size and shape of individual cells. This involves a vast array of genes and proteins, and requires sophisticated mechanisms to keep them acting in step. Two reports in this issu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7a59a5b410381b33fb3d16eb185afae
https://doi.org/10.1038/nature07050
https://doi.org/10.1038/nature07050
Publikováno v:
International Journal of Mass Spectrometry. 268:93-105
We describe a prototype tandem mass spectrometer that is designed to increase the efficiency of linked-scan analyses by >100-fold over conventional linked-scan instruments. The key element of the mass spectrometer is a novel high ion capacity ion tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e86a3e72d502b382514f1c95aee1a955
https://doi.org/10.1016/j.ijms.2007.06.015
https://doi.org/10.1016/j.ijms.2007.06.015
Autor:
Srihari C. Sampath, Alexander Tarakhovsky, Agnes Viale, Ming-Ming Zhou, Ingrid Mecklenbräuker, Eugene Rudensky, Ivan Marazzi, Andrew N. Krutchinsky, Brian T. Chait, Srinath C Sampath, Kyoko L. Yap
Publikováno v:
Molecular Cell. 27(4):596-608
Epigenetic gene silencing in eukaryotes is regulated in part by lysine methylation of the core histone proteins. While histone lysine methylation is known to control gene expression through the recruitment of modification-specific effector proteins,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4597dbd0d231d75e8b2dd696ed4525d3
Autor:
Andrew N. Krutchinsky, Xiaoting Zhang, Brian T. Chait, Robert G. Roeder, Wei Chen, Soichiro Yamamura, Aya Fukuda
Publikováno v:
Molecular Cell. 19:89-100
Human TRAP/Mediator is a key coactivator for many transcription factors that act through direct interactions with distinct subunits, and MED1/TRAP220 is the main subunit target for various nuclear receptors. Remarkably, the current study shows that M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c63104987bf45b8a7af1ce0939b1dbf
https://doi.org/10.1016/j.molcel.2005.05.015
https://doi.org/10.1016/j.molcel.2005.05.015