Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Andrew N. Gifford"'
Autor:
Omar Alijevic, Oihane Jaka, Ainhoa Alzualde, Diana Maradze, Wenhao Xia, Stefan Frentzel, Andrew N. Gifford, Manuel C. Peitsch, Julia Hoeng, Kyoko Koshibu
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Alkaloids that target nicotinic acetylcholine receptors (nAChR) are of great interest because of the critical role they play in mood and anxiety. However, understanding of the neuropharmacological effects of nicotinic alkaloids, such as cotinine and
Externí odkaz:
https://doaj.org/article/925b8dd9ceda4d1e880f07f68ae43631
Autor:
Keshun Yu, Juliana Moreira Soares, Mihir Kumar Mandal, Caixia Wang, Bidisha Chanda, Andrew N. Gifford, Joanna S. Fowler, Duroy Navarre, Aardra Kachroo, Pradeep Kachroo
Publikováno v:
Cell Reports, Vol 3, Iss 4, Pp 1266-1278 (2013)
Systemic acquired resistance (SAR), a highly desirable form of plant defense, provides broad-spectrum immunity against diverse pathogens. The recent identification of seemingly unrelated chemical inducers of SAR warrants an investigation of their mut
Externí odkaz:
https://doaj.org/article/61b868a29ca847c2acc91d54d0dbc755
Publikováno v:
Molecular Imaging and Biology. 19:837-845
Purpose LRRK2 (leucine-rich repeat kinase 2) has recently been proven to be a promising drug target for Parkinson’s disease (PD) due to an apparent enhanced activity caused by mutations associated with familial PD. To date, there have been no repor
Publikováno v:
Molecular imaging and biology. 19(6)
Publikováno v:
Molecular imaging and biology. 19(6)
LRRK2 (leucine-rich repeat kinase 2) has recently been proven to be a promising drug target for Parkinson's disease (PD) due to an apparent enhanced activity caused by mutations associated with familial PD. To date, there have been no reports in whic
Publikováno v:
Molecular Plant Pathology. 15:275-283
Several genes in the Agrobacterium tumefaciens transferred (T)-DNA encode proteins that are involved in developmental alterations, leading to the formation of tumours in infected plants. We investigated the role of the protein encoded by the Atu6002
Autor:
Juliana Moreira Soares, Andrew N. Gifford, Joanna S. Fowler, Mihir K. Mandal, Pradeep Kachroo, Aardra Kachroo, Bidisha Chanda, Keshun Yu, Duroy A. Navarre, Caixia Wang
Publikováno v:
Cell Reports, Vol 3, Iss 4, Pp 1266-1278 (2013)
SummarySystemic acquired resistance (SAR), a highly desirable form of plant defense, provides broad-spectrum immunity against diverse pathogens. The recent identification of seemingly unrelated chemical inducers of SAR warrants an investigation of th
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 55:441-446
Fluorinated and deoxysucrose analogues have been proven useful in probing the substrate specificity and roles of sucrose processing enzymes and transporters in plants. To synthesize an 18F-labeled fluorodeoxysucrose analogue suitable for in vivo stud
Autor:
Andrew N. Gifford, Markus Piel, Sung Won Kim, Ben Babst, Joanna S. Fowler, Frank Rösch, Marcel Best
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 55:39-43
A recent report that the aliphatic dicarboxylic acid, azelaic acid (1,9-nonanedioic acid) but not related acids, suberic acid (1,8-octanedioic acid) or sebacic (1,10-decanedioic acid) acid induces systemic acquired resistance to invading pathogens in
Autor:
Helene Benveniste, Yu Ma, Igor Feinstein, Patrick R. Hof, Samuel C. Grant, Andrew N. Gifford, S. David Smith, Jasbeer Dhawan, Congwu Du
Publikováno v:
Annals of the New York Academy of Sciences. 1097:12-29
The wide variety of transgenic mouse models of Alzheimer's disease (AD) reflects the search for specific genes that influence AD pathology and the drive to create a clinically relevant animal model. An ideal AD mouse model must display hallmark AD pa