Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Andrew N. Bayne"'
Publikováno v:
PLoS ONE, Vol 18, Iss 4 (2023)
Mitochondrial dysfunction is implicated in a wide array of human diseases ranging from neurodegenerative disorders to cardiovascular defects. The coordinated localization and import of proteins into mitochondria are essential processes that ensure mi
Externí odkaz:
https://doaj.org/article/79a55dcf676d4ddb8019c6c1a9e1d7a2
Publikováno v:
PLOS ONE. 18:e0284541
SummaryMitochondrial dysfunction is implicated in a wide array of human diseases ranging from neurodegenerative disorders to cardiovascular defects. The coordinated localization and import of proteins into mitochondria are essential processes that en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a54d9cb680d851cf8a2e0879f59bacb
https://doi.org/10.1371/journal.pone.0284541
https://doi.org/10.1371/journal.pone.0284541
Autor:
Jing Dong, Anthony Duchesne, Andrew N. Bayne, Nguyen-Vi Mohamed, Wei Yi, Meghna Mathur, Carol X.Q. Chen, Zhipeng You, Narges Abdian, Lorne Taylor, Edward A. Fon, Thomas M. Durcan, Jean-François Trempe
Publikováno v:
Methods (San Diego, Calif.). 203
Patient-derived organoids from induced pluripotent stem cells have emerged as a model for studying human diseases beyond conventional two-dimensional (2D) cell culture. Briefly, these three-dimensional organoids are highly complex, capable of self-or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7f0acc2b855728c4cf79d8b9edc9e3
https://pubmed.ncbi.nlm.nih.gov/35331912
https://pubmed.ncbi.nlm.nih.gov/35331912
Autor:
Thomas M. Durcan, Jean-François Trempe, Edward A. Fon, Duchesne A, Meghna Mathur, Wei Yi, Andrew N. Bayne, Dong J, Nguyen-Vi Mohamed
Patient-derived organoids from induced pluripotent stem cells have emerged as a model for studying human diseases beyond conventional two-dimensional (2D) cell culture. Briefly, these three-dimensional organoids are highly complex, capable of self-or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2402405094c95825fec46dbd855aebd2
https://doi.org/10.1101/2021.09.30.462679
https://doi.org/10.1101/2021.09.30.462679
Autor:
Jean-François Trempe, Andrew N. Bayne, Dominique Lévesque, Rosalind F. Roberts, François-Michel Boisvert, Thomas Goiran, Edward A. Fon
Publikováno v:
Journal of proteome research. 20(1)
The generation of mitochondrial-derived vesicles (MDVs) is implicated in a plethora of vital cell functions, from mitochondrial quality control to peroxisomal biogenesis. The discovery of distinct subtypes of MDVs has revealed the selective inclusion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29de806e2ec634bed8b5ba640f18f8e0
https://pubmed.ncbi.nlm.nih.gov/33242952
https://pubmed.ncbi.nlm.nih.gov/33242952
Publikováno v:
Trends in cell biology. 30(6)
Given their polyvalent functions, an inherent challenge that mitochondria face is the exposure to mitochondrial import stresses, culminating in their dysfunction. Recently, mitochondrial import of several mitochondrial substrates was shown to be regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bfc4b9e3c2dd61d7d9d2601ddef42c9
https://pubmed.ncbi.nlm.nih.gov/32345464
https://pubmed.ncbi.nlm.nih.gov/32345464
Autor:
Alexandra T. Star, Heidi M. McBride, Thomas M. Durcan, Elizabeth M. Meiering, Myriam Gagné, Janice Robertson, Christine Vande Velde, Jean-François Trempe, Sabrina Semmler, Neil R. Cashman, Pranav Garg, Elise Caron, Andrew N. Bayne, Nathalie Grandvaux, Steven S. Plotkin, Laurie Destroismaisons, Yousra Khalfallah, Sarah Pickles, Charlotte Baudouin, Mathilde Chaineau, Arsalan S. Haqqani, Emeline Hamon-Keromen
Publikováno v:
J Biol Chem
Amyotrophic lateral sclerosis (ALS) is a fatal disease, characterized by the selective loss of motor neurons leading to paralysis. Mutations in the gene encoding superoxide dismutase 1 (SOD1) are the second most common cause of familial ALS, and cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e140f4f50d7b9cd9106484395b1381a
https://nrc-publications.canada.ca/eng/view/object/?id=a04144de-e1cd-4b3e-a9fd-85a9f8650044
https://nrc-publications.canada.ca/eng/view/object/?id=a04144de-e1cd-4b3e-a9fd-85a9f8650044
Autor:
Dylan Pelletier, Khanh Huy Bui, Corbin Black, Andrew N. Bayne, Muneyoshi Ichikawa, Nimra Khan, Simon Veyron, Ahmad Abdelzaher Zaki Khalifa, Igor Kurinov, Susanne Bechstedt, Thomas S. McAlear, Jean-François Trempe, Sami Chaaban, Gary J. Brouhard, Nathalie Croteau
Publikováno v:
Structure
The Parkin co-regulated gene protein (PACRG) binds at the inner junction between doublet microtubules of the axoneme, a structure found in flagella and cilia. PACRG binds to the adaptor protein meiosis expressed gene 1 (MEIG1), but how they bind to m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::debe9c0408b27d3d4459e692128399f0
https://doi.org/10.1016/j.str.2021.01.001
https://doi.org/10.1016/j.str.2021.01.001
Autor:
Steven S. Plotkin, Neil R. Cashman, Elise Caron, Laurie Destroismaisons, Alexandra T. Star, Mathilde Chaineau, Andrew N. Bayne, Charlotte Baudouin, Christine Vande Velde, Thomas M. Durcan, Yousra Khalfallah, Elizabeth M. Meiering, Heidi M. McBride, Myriam Gagné, Pranav Garg, Janice Robertson, Sabrina Semmler, Sarah Pickles, Arsalan S. Haqqani, Nathalie Grandvaux, Jean-François Trempe, Emeline Hamon-Keromen
Amyotrophic lateral sclerosis (ALS) is a fatal disease, characterized by the selective loss of motor neurons leading to paralysis. Mutations in the gene encoding superoxide dismutase1(SOD1) are the second most common cause of familial ALS, and consid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::231767bf007cffe9a8e0311f65929bfb
Autor:
Andrew N. Bayne, Jean-François Trempe
Publikováno v:
Cellular and molecular life sciences : CMLS. 76(23)
Parkinson's disease (PD) is a degenerative movement disorder resulting from the loss of specific neuron types in the midbrain. Early environmental and pathophysiological studies implicated mitochondrial damage and protein aggregation as the main caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d49c03605b1281cdd4aabb50df69d6
https://pubmed.ncbi.nlm.nih.gov/31254044
https://pubmed.ncbi.nlm.nih.gov/31254044