Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Andrew N Freedman"'
Publikováno v:
Frontiers in Genetics, Vol 5 (2014)
Cancer pharmacogenomics have contributed a number of important discoveries to current cancer treatment, changing the paradigm of treatment decisions. Both somatic and germline mutations are utilized to better understand the underlying biology of canc
Externí odkaz:
https://doaj.org/article/73fb0bef040b4c10865dd3f6892b3d61
Autor:
A. Cecile J.W. Janssens, Cornelia M. van Duijn, Andrew N. Freedman, Suman Kundu, Jeroen B. van der Net, Moniek van Zitteren
Background: Genome-wide association studies identified novel breast cancer susceptibility variants that could be used to predict breast cancer in asymptomatic women. This review and modeling study aimed to investigate the current and potential predic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ee6f6c8eb80b4df218e016c98f7f81
https://doi.org/10.1158/1055-9965.c.6515094.v1
https://doi.org/10.1158/1055-9965.c.6515094.v1
Autor:
A. Cecile J.W. Janssens, Cornelia M. van Duijn, Andrew N. Freedman, Suman Kundu, Jeroen B. van der Net, Moniek van Zitteren
Hypothesis/Commentary for This Article from Genome-Based Prediction of Breast Cancer Risk in the General Population: A Modeling Study Based on Meta-Analyses of Genetic Associations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a20a3d283a969bd68f45fb7145ae826
https://doi.org/10.1158/1055-9965.22435770
https://doi.org/10.1158/1055-9965.22435770
Autor:
Lisa P. Spees, Eboneé N. Butler, Andrew N. Freedman, William M. P. Klein, Irene Prabhu Das, Janet S. de Moor, Megan C. Roberts
Publikováno v:
JCO Precis Oncol
PURPOSE This study examines oncologist-reported reasons for not using multimarker tumor panel testing and the association between these reasons and oncologist-level, facility-level, and patient-mix characteristics. METHODS We used data collected from
Autor:
Stephen E. Kimmel, Wei Zhou, Kelly K. Filipski, Andrew N. Freedman, Gillian Bartlett, Bruce Carleton, Amalia M. Issa, Geoffrey Liu, Cristina Longo, Anke H. Maitland-van der Zee, Leah B Sansbury, Tobias Gerhard
Publikováno v:
Pharmacoepidemiology and drug safety. 30(8):985-992
The advent of the genomic age has created a rapid increase in complexity for the development and selection of drug treatments. A key component of precision medicine is the use of genetic information to improve therapeutic effectiveness of drugs and p
Autor:
Mary Lou Smith, Liz Garrett-Mayer, Julianne S Dieterich, Janet S. de Moor, Stacy W. Gray, Hong Zhu, Suanna S. Bruinooge, Jason Y. Park, Anh Quynh Hoang, Mitchell S. von Itzstein, David E. Gerber, Carol B. White, Andrew N. Freedman, Elda Railey, Jingsheng Yan
Publikováno v:
JCO Oncol Pract
PURPOSE: Advances in genomic techniques have led to increased use of next-generation sequencing (NGS). We evaluated the extent to which these tests guide treatment decisions. METHODS: We developed and distributed a survey assessing NGS use and outcom
Autor:
Andrew N. Freedman, Elizabeth M. Gillanders, Kelly K. Filipski, Scott W. Rogers, Tram Kim Lam, Damali N. Martin, Stefanie A. Nelson, Rolando Barajas, Melissa Rotunno, Danielle Daee, Lisa Gallicchio, Rao L. Divi, Mukesh Verma, Danielle M. Carrick, Sarah Fagan
Publikováno v:
Cancer Epidemiol Biomarkers Prev
Background: The goals of this project were to assess the status of NCI's rare cancer–focused population science research managed by the Division of Cancer Control and Population Sciences (DCCPS), to develop a framework for evaluation of rare cancer
Autor:
Andrew N. Freedman, Lisa P. Spees, Eboneé N. Butler, Irene Prabhu Das, Megan C. Roberts, William M. P. Klein, Janet S. de Moor
Publikováno v:
Patient Educ Couns
Objective Next generation sequencing (NGS) may aid in tumor classification and treatment. Barriers to shared decision-making may influence use of NGS. We examined, from oncologists’ perspectives, whether barriers to involving patients/families in d
Autor:
Michael J. Barrett, Matthew P. Banegas, Angela B. Mariotto, Donna R. Rivera, Kelly K. Filipski, Clara J K Lam, Lindsey Enewold, Andrew N. Freedman
Publikováno v:
Journal of Managed Care & Specialty Pharmacy. 26:1494-1504
BACKGROUND: Following approval of imatinib, a breakthrough tyrosine kinase inhibitor (TKI), survival significantly improved by more than 20% since 2001 among treated chronic myelogenous leukemia (CML) patients. Subsequently, more expensive second-gen
Autor:
Elad Sharon, Andrew N. Freedman, Aracelis Z. Torres, Susan Spillane, David Lenis, Angela B. Mariotto, Shrujal S. Baxi
Publikováno v:
The Oncologist
Background Real‐world data enables evaluation of immune checkpoint inhibitor (ICI) use in advanced melanoma management. We examined characteristics and outcomes of ICI‐treated patients with advanced melanoma and organ dysfunction (baseline and em