Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Andrew Mike Rauth"'
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 317:1372-1381
The objectives of this study were to evaluate the potential of a polymer-lipid hybrid nanoparticle (PLN) system to enhance cellular accumulation and retention of doxorubicin (Dox), a widely used anticancer drug and an established P-glycoprotein (Pgp)
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 65(3)
The purpose of this study is to evaluate the in vivo efficacy, unwanted toxicity and loco-regional distribution of a doxorubicin-loaded polymer-lipid hybrid nanoparticle (Dox-PLN) formulation in a murine solid tumor model after intratumoral injection
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 116(3)
Multidrug-resistant (MDR) cancer may be treated using combinations of encapsulated cytotoxic drugs and chemosensitizers. To optimize for the effectiveness of this combinational approach, novel polymer-lipid hybrid nanoparticle (PLN) formulations capa
Publikováno v:
Journal of pharmaceutical sciences. 93(8)
The purpose of this study was to develop and characterize a solid lipid nanoparticle (SLN) system containing an anionic polymer for the delivery of cationic antineoplastic agents and chemosensitizers. Ionic complexation was utilized to enhance the lo