Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Andrew Metha"'
Autor:
Paul Trlin, Jenny Gong, Katie K. N. Tran, Vickie H. Y. Wong, Pei Ying Lee, Anh Hoang, Da Zhao, Leah C. Beauchamp, Jeremiah K. H. Lim, Andrew Metha, Kevin J. Barnham, David I. Finkelstein, Bang V. Bui, Phillip Bedggood, Christine T. O. Nguyen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Retinal hyperspectral imaging (HSI) is a non-invasive in vivo approach that has shown promise in Alzheimer’s disease. Parkinson’s disease is another neurodegenerative disease where brain pathobiology such as alpha-synuclein and iron over
Externí odkaz:
https://doaj.org/article/4922d8416bbd4e5ca8336a9df43afadf
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292962 (2023)
Capillary flow is known to be non-homogenous between vessels and variable over time, for reasons that are poorly understood. The local properties of individual vessels have been shown to have limited explanatory power in this regard. This exploratory
Externí odkaz:
https://doaj.org/article/9208561ad81e431499c10e6d483011a7
Autor:
Jeremiah K. H. Lim, Qiao-Xin Li, Tim Ryan, Phillip Bedggood, Andrew Metha, Algis J. Vingrys, Bang V. Bui, Christine T. O. Nguyen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Hyperspectral imaging of the retina has recently been posited as a potentially useful form of spectroscopy of amyloid-beta (Aβ) protein in the eyes of those with Alzheimer’s disease (AD). The concept of using the retina as a biomarker for
Externí odkaz:
https://doaj.org/article/28ea0fabc8e749f5be0e21a89d4e8ea5
Autor:
Phillip Bedggood, Andrew Metha
Publikováno v:
PLoS ONE, Vol 16, Iss 6 (2021)
The high power of the eye and optical components used to image it result in “static” distortion, remaining constant across acquired retinal images. In addition, raster-based systems sample points or lines of the image over time, suffering from
Externí odkaz:
https://doaj.org/article/89bf853319d84db29a13230f4cb72044
Mapping flow velocity in the human retinal capillary network with pixel intensity cross correlation.
Autor:
Phillip Bedggood, Andrew Metha
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218918 (2019)
We present a new method for determining cellular velocity in the smallest retinal vascular networks as visualized with adaptive optics. The method operates by comparing the intensity profile of each movie pixel with that of every other pixel, after s
Externí odkaz:
https://doaj.org/article/fc0fbdb523654c72a395660ca7fc4512
Autor:
Phillip Bedggood, Andrew Metha
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174617 (2017)
A limitation of scanning laser ophthalmoscopy (SLO) is that eye movements during the capture of each frame distort the retinal image. Various sophisticated strategies have been devised to ensure that each acquired frame can be mapped quickly and accu
Externí odkaz:
https://doaj.org/article/1b6f9a2908394c11a0d4e37ddd785577
Autor:
Phillip Bedggood, Andrew Metha
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79251 (2013)
Capture of light in the photoreceptor outer segment initiates a cascade of chemical events that inhibit neurotransmitter release, ultimately resulting in vision. The massed response of the photoreceptor population can be measured non-invasively by el
Externí odkaz:
https://doaj.org/article/33690f1d34f247a0b6199d50046b2873
Publikováno v:
Biomed Opt Express
The optical density of visual pigment can be measured by imaging the dark-adapted eye while bleaching with visible light. This measurement can be made for individual photoreceptor cells using adaptive optics; however, activation of the phototransduct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7401acfdb7d2ab5d371f3a4c563b2e6c
https://pubmed.ncbi.nlm.nih.gov/36425640
https://pubmed.ncbi.nlm.nih.gov/36425640
Autor:
Andrew Metha, Phillip Bedggood
Publikováno v:
Optics letters. 46(18)
With each contraction of the heart’s left ventricle, a pulse pressure wave surges into the aorta and propagates throughout the vascular tree. The pulse wave drives blood flow forward. Its passage is complex, but it passes more quickly through non-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad2669d8500d1ce40b7c0be6f25d66d
https://pubmed.ncbi.nlm.nih.gov/34525019
https://pubmed.ncbi.nlm.nih.gov/34525019
Publikováno v:
Vision Research. 160:1-9
Even during fixation, our eyes constantly make small, involuntary eye movements that cause the retinal image to be swept across our retinae. Despite this, our world appears completely stable, due to powerful perceptual stabilisation mechanisms. Wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b91533330e20556ff06335df0a568c5d
https://doi.org/10.1016/j.visres.2019.04.007
https://doi.org/10.1016/j.visres.2019.04.007