Zobrazeno 1 - 10
of 254
pro vyhledávání: '"Andrew Menzies-Gow"'
Autor:
John Haughney, Trung N. Tran, Heath Heatley, Arnaud Bourdin, Andrew Menzies-Gow, David J. Jackson, Ekaterina Maslova, Jatin Chapaneri, Derek Skinner, Victoria Carter, Jeffrey Shi Kai Chan, David Price
Publikováno v:
npj Primary Care Respiratory Medicine, Vol 33, Iss 1, Pp 1-5 (2023)
Abstract An algorithm to describe patterns of intermittent oral corticosteroid use in the UK (n = 476,167) found that one-third of patients receiving intermittent oral corticosteroids for asthma only had short gaps (
Externí odkaz:
https://doaj.org/article/671d13db0b624043963fa8035203f4ad
Autor:
Tamotsu Ishizuka, Andrew Menzies-Gow, Hiroshi Okada, Yasushi Fukushima, Nobuya Hayashi, Gene Colice, Sandhia Ponnarambil, Gillian Hunter, Hiroshi Odajima, Motohiro Ebisawa
Publikováno v:
Allergology International, Vol 72, Iss 1, Pp 82-88 (2023)
Background: Tezepelumab, a human monoclonal antibody, blocks the activity of thymic stromal lymphopoietin. In the phase 3 NAVIGATOR study (NCT03347279), tezepelumab reduced exacerbations by 56% compared with placebo in adults and adolescents with sev
Externí odkaz:
https://doaj.org/article/9bd942d749d64d6dbc329b25ddc88795
Autor:
Ronald McDowell, Liam Heaney, Thomas Brown, Brendan Bunting, Hassan Burhan, Rekha Chaudhuri, Paddy Dennison, Shoaib Faruqi, Robin Gore, David J Jackson, Andrew Menzies-Gow, Thomas Pantin, Mitesh Patel, Paul Pfeffer, Salman Siddiqui, John Busby, UK Severe Asthma Registry
Publikováno v:
PLoS ONE, Vol 18, Iss 12, p e0295493 (2023)
BackgroundThe Asthma Control Questionnaire (ACQ) is used to assess asthma symptom control. The relationship between the questionnaire items and symptom control has not been fully studied in severe asthmatic patients, and its validity for making compa
Externí odkaz:
https://doaj.org/article/c70787ad03fa4ebeb84ba63d14041e19
Autor:
Andrew Menzies-Gow, Sandhia Ponnarambil, John Downie, Karin Bowen, Åsa Hellqvist, Gene Colice
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background Tezepelumab is a human monoclonal antibody that blocks the activity of the epithelial cytokine thymic stromal lymphopoietin. The efficacy, safety and oral corticosteroid-sparing potential of tezepelumab are being investigated in t
Externí odkaz:
https://doaj.org/article/666023d7ad3246cfacc77010fc431de5
Autor:
Andrew Menzies-Gow, Gene Colice, Janet M. Griffiths, Gun Almqvist, Sandhia Ponnarambil, Primal Kaur, Gennaro Ruberto, Karin Bowen, Åsa Hellqvist, May Mo, Esther Garcia Gil
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background Patients with severe, uncontrolled asthma have a significant unmet need for new treatments that have broader effects on airway inflammation, and that provide greater improvements in asthma outcomes than currently approved biologic
Externí odkaz:
https://doaj.org/article/1d95b73b0f56448095c718271556d711
Autor:
Joseph W. Lanario, Michael E. Hyland, Andrew Menzies-Gow, Adel H. Mansur, James W. Dodd, Stephen J. Fowler, Rupert C. Jones, Matthew Masoli
Publikováno v:
Health and Quality of Life Outcomes, Vol 18, Iss 1, Pp 1-10 (2020)
Abstract Background The Severe Asthma Questionnaire (SAQ) is a health related quality of life (HRQoL) questionnaire validated for use in severe asthma. It is scored using the mean value of 16 items (SAQ score) in addition to a single item global rati
Externí odkaz:
https://doaj.org/article/11d1035f5c4c4367aacea9d0ab280935
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-7 (2020)
Abstract Despite treatment with standard-of-care medications, including currently available biologic therapies, many patients with severe asthma have uncontrolled disease, which is associated with a high risk of hospitalization and high healthcare co
Externí odkaz:
https://doaj.org/article/51d5a4ee08ab4efe94db883c60d3884e
Autor:
J. Mark FitzGerald, Trung N. Tran, Marianna Alacqua, Alan Altraja, Vibeke Backer, Leif Bjermer, Unnur Bjornsdottir, Arnaud Bourdin, Guy Brusselle, Lakmini Bulathsinhala, John Busby, Giorgio W. Canonica, Victoria Carter, Isha Chaudhry, You Sook Cho, George Christoff, Borja G. Cosio, Richard W. Costello, Neva Eleangovan, Peter G. Gibson, Liam G. Heaney, Enrico Heffler, Mark Hew, Naeimeh Hosseini, Takashi Iwanaga, David J. Jackson, Rupert Jones, Mariko S. Koh, Thao Le, Lauri Lehtimäki, Dora Ludviksdottir, Anke H. Maitland-van der Zee, Andrew Menzies-Gow, Ruth B. Murray, Nikolaos G. Papadopoulos, Luis Perez-de-Llano, Matthew Peters, Paul E. Pfeffer, Todor A. Popov, Celeste M. Porsbjerg, Chris A. Price, Chin K. Rhee, Mohsen Sadatsafavi, Yuji Tohda, Eileen Wang, Michael E. Wechsler, James Zangrilli, David B. Price
Publikováno v:
BMC Medical Research Methodology, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background Severe asthma exerts a disproportionately heavy burden on patients and health care. Due to the heterogeneity of the severe asthma population, many patients need to be evaluated to understand the clinical features and outcomes of s
Externí odkaz:
https://doaj.org/article/e54dcc26c659484a946707247a18094b
Autor:
Steven J. Smith, John Busby, Liam G. Heaney, Paul E. Pfeffer, David J. Jackson, Freda Yang, Stephen J. Fowler, Andrew Menzies-Gow, Elfatih Idris, Thomas Brown, Robin Gore, Shoaib Faruqi, Paddy Dennison, James W. Dodd, Simon Doe, Adel H. Mansur, Radhika Priyadarshi, Joshua Holmes, Andrew Hearn, Hamsa Al-Aqqad, Lola Loewenthal, Angela Cooper, Lauren Fox, Mayurun Selvan, Michael G. Crooks, Alison Thompson, Daniel Higbee, Michelle Fawdon, Vishal Nathwani, LeanneJo Holmes, Rekha Chaudhuri
Publikováno v:
ERJ Open Research, Vol 7, Iss 1 (2021)
Externí odkaz:
https://doaj.org/article/03b4c23120c8423c9c3a95708a38e23a
Autor:
Catherine E. Hanratty, John G. Matthews, Joseph R. Arron, David F. Choy, Ian D. Pavord, P. Bradding, Christopher E. Brightling, Rekha Chaudhuri, Douglas C. Cowan, Ratko Djukanovic, Nicola Gallagher, Stephen J. Fowler, Tim C. Hardman, Tim Harrison, Cécile T. Holweg, Peter H. Howarth, James Lordan, Adel H. Mansur, Andrew Menzies-Gow, Sofia Mosesova, Robert M. Niven, Douglas S. Robinson, Dominick E. Shaw, Samantha Walker, Ashley Woodcock, Liam G. Heaney, on behalf of the RASP-UK (Refractory Asthma Stratification Programme) Consortium
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-13 (2018)
Abstract Background Patients with difficult-to-control asthma consume 50–60% of healthcare costs attributed to asthma and cost approximately five-times more than patients with mild stable disease. Recent evidence demonstrates that not all patients
Externí odkaz:
https://doaj.org/article/8b2b5c94718a45699e6b6b269b64f460