Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Andrew Melville"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract In a cardiac output (CO) sub-study of the Restrictive versus Liberal Fluid Therapy in Major Abdominal Surgery (RELIEF) trial, it was shown that restrictive fluid management was associated with lower cardiac index at the end of surgery. Howev
Externí odkaz:
https://doaj.org/article/50511d3944cc41ff8cb90820bcdb54c2
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Cardiovascular disease accounts for millions of deaths each year and is currently the leading cause of mortality worldwide. The aging process is clearly linked to cardiovascular disease, however, the exact relationship between aging and heart functio
Externí odkaz:
https://doaj.org/article/dc2ee6487edd43af951ea85a6e437964
Autor:
Marc Lipman, Elisha Pickett, Alison Rodger, Margaret Johnson, James Brown, Christianna Kyriacou, Kelly Edwards, Hemal Joshi, Nafeesah Stewart, Andrew Melville, Jan Flint, Angela Bartley
Publikováno v:
BMJ Open Respiratory Research, Vol 6, Iss 1 (2019)
Introduction People living with HIV (PLWH) are more likely to smoke than the general population and are at greater risk of smoking-related illness. Healthcare services need to address this burden of preventable disease.Methods We evaluated the impact
Externí odkaz:
https://doaj.org/article/6633b855eea547b083b088a2803840b1
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
The treatment of rheumatoid arthritis (RA) has been transformed with the introduction of biologic disease modifying anti-rheumatic drugs (bDMARD) and more recently, targeted synthetic DMARD (tsDMARD) therapies in the form of janus-kinase inhibitors.
Externí odkaz:
https://doaj.org/article/ca0b57f4014945c89d6d1461d71c76f8
Autor:
Andrew Melville
Publikováno v:
Rheumatology Advances in Practice. 6
Introduction/Background Dactylitis is a hallmark feature of PsA (PsA) and related spondyloarthritides and may affect up to half of PsA patients during the course of their disease(1). Presence of dactylitis may imply a more aggressive disease phenotyp
Publikováno v:
Fitton, J, Melville, A R, Emery, P, Nam, J L & Buch, M H 2020, ' Real-world single centre use of JAK inhibitors across the rheumatoid arthritis pathway ', Rheumatology . https://doi.org/10.1093/rheumatology/keaa858
Objectives To evaluate real-world efficacy of approved JAK inhibitors (JAKi) tofacitinib and baricitinib in a large, single-centre cohort of RA patients across the treatment pathway, including those refractory to multiple biologic drugs. Methods All
Autor:
John Fitton, Andrew Melville
Publikováno v:
Orthopaedics and Trauma. 33:204-211
Autor:
Benazir Saleem, Lynda Bailey, Shouvik Dass, Paul Emery, Andrew Melville, L. Garcia-Montoya, Maya H Buch, Yuzaiful Md Yusof, John Fitton
Publikováno v:
Rheumatology.
Objective To evaluate the impact of non-medical switch from rituximab originator (RTX-O) to biosimilar (RTX-B) in patients with RA. Methods Between October 2017 and October 2019, all patients on RTX-O in our centre requiring re-treatment were switche
Publikováno v:
Rheumatology. 59
Background There has been a national cost-saving drive to switch from originator rituximab (RTX-O) to biosimilar (RTX-B). Whilst regulatory clinical trials necessitate demonstration of equivalence, subtle physicochemical changes could theoretically a
Publikováno v:
Critical Care Medicine
Supplemental Digital Content is available in the text.
Objectives: To describe the characteristics, circumstances, change over time, resource use, and outcomes of patients admitted to ICUs in Australia and New Zealand for the purposes of “pall
Objectives: To describe the characteristics, circumstances, change over time, resource use, and outcomes of patients admitted to ICUs in Australia and New Zealand for the purposes of “pall