Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Andrew McKinney"'
Autor:
Andrew McKinney, Ming Hu, Amber Hoskins, Arian Mohammadyar, Nabeeha Naeem, Junzhan Jing, Saumil S Patel, Bhavin R Sheth, Xiaolong Jiang
Publikováno v:
eLife, Vol 12 (2023)
The locus coeruleus (LC) houses the vast majority of noradrenergic neurons in the brain and regulates many fundamental functions, including fight and flight response, attention control, and sleep/wake cycles. While efferent projections of the LC have
Externí odkaz:
https://doaj.org/article/dfb6e6cbb9a34f068098389bb06e2211
Autor:
Savannah J. Lusk, Andrew McKinney, Patrick J. Hunt, Paul G. Fahey, Jay Patel, Andersen Chang, Jenny J. Sun, Vena K. Martinez, Ping Jun Zhu, Jeremy R. Egbert, Genevera Allen, Xiaolong Jiang, Benjamin R. Arenkiel, Andreas S. Tolias, Mauro Costa-Mattioli, Russell S. Ray
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-26 (2022)
Abstract Background The functional understanding of genetic interaction networks and cellular mechanisms governing health and disease requires the dissection, and multifaceted study, of discrete cell subtypes in developing and adult animal models. Re
Externí odkaz:
https://doaj.org/article/b89d316edd62446cad90e9bc7fa9951d
Autor:
Nicholas Stevers, Carter Barger, Jimmy Yuan, Somang Kim, Chibo Hong, Olivia Lenzo, Andrew McKinney, Samuel Wu, Yu-Jin Lee, Darwin Kwok, Abigail Suwala, Christina Appin, John D. Gordan, Annette Molinaro, Jun Song, Joseph Costello
Activating mutations in the Telomerase Reverse Transcriptase (TERT) promoter are the single most common non-coding mutation in cancer and enable limitless cell division characteristic of immortal cells1–12. Solving the immortality mechanism represe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d868bcb291a7bbf7b80aacf31a2b1e5e
https://doi.org/10.21203/rs.3.rs-2849176/v1
https://doi.org/10.21203/rs.3.rs-2849176/v1
Autor:
Joanna J. Phillips, William A. Weiss, Monika E. Hegi, Albert Lai, William H. Yong, Theodore P. Nicolaides, C. David James, Joseph T.C. Shieh, Mitchel S. Berger, Andrew W. Bollen, Michael Prados, Linda M. Liau, Timothy F. Cloughesy, Erin F. Simonds, Kan V. Lu, Henry Gong, Anupam Kumar, Katharine Y. Chen, Jane R. Engler, Olle R. Lindberg, Andrew McKinney
Supplementary Figure S1 shows increased invasion is specific to EGFR inhibition, increased ALDH1A1 expression is not specific to erlotinib but also occurs with AG1478 and lapatinib, and EGFR inhibition increases expression of several genes implicated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00141c8ad56ed4fbd4e04e650a02b942
https://doi.org/10.1158/1535-7163.22506199
https://doi.org/10.1158/1535-7163.22506199
Autor:
Joanna J. Phillips, William A. Weiss, Monika E. Hegi, Albert Lai, William H. Yong, Theodore P. Nicolaides, C. David James, Joseph T.C. Shieh, Mitchel S. Berger, Andrew W. Bollen, Michael Prados, Linda M. Liau, Timothy F. Cloughesy, Erin F. Simonds, Kan V. Lu, Henry Gong, Anupam Kumar, Katharine Y. Chen, Jane R. Engler, Olle R. Lindberg, Andrew McKinney
Amplification of the epidermal growth factor receptor gene (EGFR) represents one of the most commonly observed genetic lesions in glioblastoma (GBM); however, therapies targeting this signaling pathway have failed clinically. Here, using human tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab7e13d5ba0dbfc1f50b929a8ae3a3d
https://doi.org/10.1158/1535-7163.c.6538321.v1
https://doi.org/10.1158/1535-7163.c.6538321.v1
Autor:
Andrew McKinney, Ming Hu, Amber Hoskins, Arian Mohammadyar, Nabeeha Naeem, Junzhan Jing, Saumil S Patel, Bhavin R Sheth, Xiaolong Jiang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea97169cdf225c0b5bd5f07ff4350e66
https://doi.org/10.7554/elife.80100.sa2
https://doi.org/10.7554/elife.80100.sa2
Autor:
Andrew McKinney, Ming Hu, Amber Hoskins, Arian Mohammadyar, Nabeeha Naeem, Junzhan Jing, Saumil S. Patel, Bhavin R. Sheth, Xiaolong Jiang
The locus coeruleus (LC) houses the vast majority of noradrenergic neurons in the brain and regulates many fundamental functions including fight and flight response, attention control, and sleep/wake cycles. While efferent projections of the LC have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82aedb6bc059d6383bf66beff6117a93
https://doi.org/10.1101/2022.03.01.481656
https://doi.org/10.1101/2022.03.01.481656
Autor:
Chibo Hong, Carter J. Barger, Andrew McKinney, Olivia Lenzo, Joseph F. Costello, Nicholas Stevers
Publikováno v:
Neuro Oncol
Tumor cell immortality is a fundamental hallmark of human cancers. Normally silenced during somatic cell differentiation, 90% of human tumors reactivate Telomerase Reverse Transcriptase (TERT) expression to achieve cellular immortality. TERT, the cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df1407eadf174b2f7d11aa97f233d0a1
https://europepmc.org/articles/PMC8598615/
https://europepmc.org/articles/PMC8598615/
Autor:
Savannah J. Lusk, Andrew McKinney, Patrick J. Hunt, Paul G. Fahey, Jay Patel, Andersen Chang, Jenny J. Sun, Vena K. Martinez, Ping Jun Zhu, Jeremy R. Egbert, Genevera Allen, Xiaolong Jiang, Benjamin R. Arenkiel, Andreas S. Tolias, Mauro Costa-Mattioli, Russell S. Ray
BackgroundA full understanding of circuits and cellular mechanisms governing health and disease requires the dissection and multi-faceted study of discrete cell subtypes in developing and adult animal models. Recombinase-driven expression of transgen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::161c9054d8b1a9c3b7e74a8a00d75fb1
https://doi.org/10.1101/2021.06.10.447908
https://doi.org/10.1101/2021.06.10.447908
Publikováno v:
The FASEB Journal. 35