Výsledky vyhledávání - "Andrew McGuire"

Akademický článek

Peripheral Blood Cell Ratios as Prognostic Indicators in a Neoadjuvant Chemotherapy-Treated Breast Cancer Cohort

Autor: Amirhossein Jalali, David Miresse, Matthew R. Fahey, Niamh Ni Mhaonaigh, Andrew McGuire, Emer Bourke, Michael J. Kerin, James A. L. Brown

Publikováno v: Current Oncology, Vol 29, Iss 10, Pp 7512-7523 (2022)

Breast cancer represents a heterogeneous condition in which the interaction between host immune response and primary oncogenic events can impact disease progression. Ratios of systemic blood-based immunocytes have emerged as clinically-relevant progn

Externí odkaz: https://doaj.org/article/91167e5e32da448fb6ed12c82562938d

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Akademický článek

Hair of the Dog? Periprosthetic Joint Infection with Streptococcus canis

Autor: Andrew McGuire, MD, BSc, Nicole Krysa, BSc, BDes, MD, Steve Mann, MD, MMEd, FRCS(C)

Publikováno v: Arthroplasty Today, Vol 8, Iss , Pp 53-56 (2021)

A 61-year-old man underwent elective primary total hip arthroplasty at an academic center and presented to the emergency department 2 weeks later with a periprosthetic infection. Intraoperative cultures were positive for Streptococcus canis. He was s

Externí odkaz: https://doaj.org/article/5b5df1143ec043e4982bdcc96ba8e291

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Akademický článek

Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization

Autor: K. Rachael Parks, Anna J. MacCamy, Josephine Trichka, Matthew Gray, Connor Weidle, Andrew J. Borst, Arineh Khechaduri, Brittany Takushi, Parul Agrawal, Javier Guenaga, Richard T. Wyatt, Rhea Coler, Michael Seaman, Celia LaBranche, David C. Montefiori, David Veesler, Marie Pancera, Andrew McGuire, Leonidas Stamatatos

Publikováno v: Cell Reports, Vol 29, Iss 10, Pp 3060-3072.e7 (2019)

Summary: Broadly HIV-1 neutralizing VRC01 class antibodies target the CD4-binding site of Env. They are derived from VH1-2∗02 antibody heavy chains paired with rare light chains expressing 5-amino acid-long CDRL3s. They have been isolated from infe

Externí odkaz: https://doaj.org/article/186a0f36c95d41e39e24afbc11ee4f79

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Akademický článek

Breast cancer subtype discordance: impact on post-recurrence survival and potential treatment options

Autor: Peter F. McAnena, Andrew McGuire, A. Ramli, C. Curran, C. Malone, R. McLaughlin, K. Barry, James A.L. Brown, M. J. Kerin

Publikováno v: BMC Cancer, Vol 18, Iss 1, Pp 1-8 (2018)

Abstract Background Recent studies have shown that breast cancer subtype can change from the primary tumour to the recurrence. Discordance between primary and recurrent breast cancer has implications for further treatment and ultimately prognosis. Th

Externí odkaz: https://doaj.org/article/b042a255a6ea45f7b4c678e688db5ffa

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