Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Andrew Mark, Scott"'
Autor:
Pathum Thilakasiri, Jennifer Huynh, Ashleigh R Poh, Chin Wee Tan, Tracy L Nero, Kelly Tran, Adam C Parslow, Shoukat Afshar‐Sterle, David Baloyan, Natalie J Hannan, Michael Buchert, Andrew Mark Scott, Michael DW Griffin, Frederic Hollande, Michael W Parker, Tracy L Putoczki, Matthias Ernst, Ashwini L Chand
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 4, Pp 1-15 (2019)
Abstract Excessive signaling through gp130, the shared receptor for the interleukin (IL)6 family of cytokines, is a common hallmark in solid malignancies and promotes their progression. Here, we established the in vivo utility of bazedoxifene, a ster
Externí odkaz:
https://doaj.org/article/f3ddb855617e4e378193d6b8beddb2bb
Autor:
Hui Kong Gan, Bryan W. Day, Rosemary Harrup, Terrance G. Johns, Zarnie Lwin, Andrew Mark Scott, Hao-Wen Sim, Eng-Siew Koh
Publikováno v:
Current Oncology Reports. 25:589-598
Autor:
Sze Ting Lee, Niall Tebbutt, Hui Kong Gan, Zhanqi Liu, John Sachinidis, Kunthi Pathmaraj, Andrew Mark Scott
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
IntroductionTumor hypoxia and angiogenesis are implicated in tumor growth and metastases, and anti-angiogenic therapies have an important role in treating patients with metastatic colorectal cancer. However, the prevalence of hypoxia has not been ful
Externí odkaz:
https://doaj.org/article/f8cf3dbca693425ca78964b7071b7db1
Autor:
Samuel Tremblay, Mofarej Alhogbani, Andrew Weickhardt, Ian D. Davis, Andrew Mark Scott, Rodney J. Hicks, Ur Metser, Sue Chua, Reena Davda, Shonit Punwani, Heather Ann Payne, Nina Tunariu, Bao Ho, Sympascho Young, Glenn Bauman, Louise Emmett, Frederic Pouliot
Publikováno v:
Journal of Clinical Oncology. 41:316-316
316 Background: The impact of molecular imaging (MI) on patient management after biochemical recurrence (BCR) following radical prostatectomy has been described in many studies. However, it is not known if MI-induced management changes are appropriat
Autor:
Brian M. Shuch, Allan J. Pantuck, Jean-Christophe Bernhard, Michael A. Morris, Viraj A. Master, Andrew Mark Scott, Charles Van Praet, Clément Bailly, Tamer Aksoy, Robin Merkx, David M. Schuster, Sze Ting Lee, Neeta Pandit-Taskar, Alice C. Fan, Libuse Tauchmanova, Phillip Allman, Kavita Vadali, Colin Hayward, Peter Mulders
Publikováno v:
Journal of Clinical Oncology. 41:LBA602-LBA602
LBA602 Background: The increasing detection of renal masses presents a significant patient management challenge. Diagnostic options include cross-sectional imaging, which cannot reliably differentiate benign and malignant renal masses, and biopsy, wh
Autor:
Malaka Ameratunga, Yuliya Perchyonok, Diana Cao, Andrew Mark Scott, Eddie Lau, Graeme O'Keefe, Angela Rigopoulos, Sze Ting Lee, Andrew B. Lassman, David Maag, Hui K Gan, Sagun Parakh, Aidan Seow, Ingrid Burvenich, Erica Gomez
Publikováno v:
Neuro-oncology Advances
BackgroundThe adverse impact of increasing brain tumor size on the efficacy of antibody-drug conjugates (ADCs) was investigated preclinically then validated with clinical data.Methods—Preclinical studyThe impact of tumor size on ADC tumor delivery
Publikováno v:
Medical physicsREFERENCES. 49(3)
A method for calculating nuclear medicine ionization chamber (NMIC) calibration settings with a Monte Carlo model is presented and validated against physical measurements. This work provides Monte Carlo-calculated calibration settings for select isot
Autor:
Ingrid Julienne Georgette, Burvenich, Yit Wooi, Goh, Nancy, Guo, Hui Kong, Gan, Angela, Rigopoulos, Diana, Cao, Zhanqi, Liu, Uwe, Ackermann, Christian Werner, Wichmann, Alexander Franklin, McDonald, Nhi, Huynh, Graeme Joseph, O'Keefe, Sylvia Jie, Gong, Fiona Elizabeth, Scott, Linghui, Li, Wanping, Geng, Anup, Zutshi, Yan, Lan, Andrew Mark, Scott
Publikováno v:
European journal of nuclear medicine and molecular imaging. 48(10)
Τhis study aimed to optimize theBintrafusp alfa (anti-PD-L1 human IgG1 antibody fused to TGF-β receptor II (TGF-βRII), avelumab (anti-PD-L1 human IgG1 control antibody), isotype control (mutated inactive anti-PD-L1 IgG1 control antibody), and trap
Autor:
Andrew Mark Scott, Diana Cao, Hui K Gan, Puey Ling Chia, Thomas John, Angela Rigopoulos, Ed Reilly, Andrew C. Phillips
Publikováno v:
Cancer Research. 78:743-743
Introduction: Malignant mesothelioma (MM) is an aggressive malignancy of the pleura with limited therapeutic options, and is associated with a poor prognosis. EGFR is known to be highly over-expressed in mesothelioma with reported EGFR overexpression
Autor:
Puey Ling Chia, Prudence A. Russell, Marzena Walkiewicz, Thomas John, Carmel Murone, Andrew Mark Scott, Ulf Eriksson
Publikováno v:
Cancer Research. 78:1557-1557
Background: Malignant mesothelioma (MM) is an aggressive malignancy of the pleura and other serosal membranes originating from mesothelial cells. Agents targeting vascular endothelial growth factor (VEGF) receptor such as bevacizumab; and multi-kinas