Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Andrew Man Lok Chan"'
Autor:
Duan Zhuo, Zhenchuan Lei, Lin Dong, Andrew Man Lok Chan, Jiacheng Lin, Liwen Jiang, Beibei Qiu, Xiaohua Jiang, Youhua Tan, Xiaoqiang Yao
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Background One of major challenges in breast tumor therapy is the existence of breast cancer stem cells (BCSCs). BCSCs are a small subpopulation of tumor cells that exhibit characteristics of stem cells. BCSCs are responsible for progression
Externí odkaz:
https://doaj.org/article/63d4c9c768ef4ea1a736da1c5c8a38ac
Autor:
Yue Guo, Donghao Guo, Shaoting Zhang, Yuan Zhang, Xiaoyan He, Xiaohua Jiang, Andrew Man-Lok Chan, Lin Zou, Jianmin Sun, Hui Zhao
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Background In neuroblastoma, hyperactivation of the PI3K signaling pathway has been correlated with aggressive neuroblastomas, suggesting PI3Ks as promising targets for the treatment of neuroblastoma. However, the oncogenic roles of individu
Externí odkaz:
https://doaj.org/article/8073261e71984b618a782130ebc512c5
Autor:
Weijie Gao, Yuliang Wang, Shan Yu, Zhu Wang, Taiyang Ma, Andrew Man-Lok Chan, Peter Ka-Fung Chiu, Chi-Fai Ng, Dinglan Wu, Franky Leung Chan
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-17 (2022)
Abstract Background Accumulating evidence supports that prostate cancer stem-like cells (PCSCs) play significant roles in therapy resistance and metastasis of prostate cancer. Many studies also show that nitric oxide (NO) synthesized by NO synthases
Externí odkaz:
https://doaj.org/article/cf2b60e01a17434980b019592587884d
Autor:
Mengqi Shi, Qianyun Ge, Xinrong Wang, Wenbin Diao, Ben Yang, Sipeng Sun, Guohui Wang, Tian Liu, Andrew Man-Lok Chan, Zhiqin Gao, Yi Wang, Yubing Wang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The glycoprotein YKL-40 has been well studied as a serum biomarker of prognosis and disease status in glioblastoma. YKL-40 is a chitinase-like protein with defective chitinase activity that plays an important role in promoting cell proliferation, mig
Externí odkaz:
https://doaj.org/article/65a70e3049c3472e9b4a62f2d7fca402
Autor:
Andrew Man-Lok Chan, Stanley Kwok-Kuen Cheung, Jacinda Kwok, Penelope Mei-Yu Or, Chi Wai Wong, Bo Feng, Kwong Wai Choy, Raymond C.C. Chang, J. Peter H. Burbach, Alfred Sze-Lok Cheng
Background: PTEN Hamartoma Tumor Syndrome (PHTS) is characterized by frequent mutation in PTEN gene. PHTS patients have numerous neurological defects including macrocephaly and autism spectrum disorder. While clinical features of PHTS are likely the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::484546bb623c668dd7ca3804d1c1cc1c
https://doi.org/10.21203/rs.3.rs-1575672/v1
https://doi.org/10.21203/rs.3.rs-1575672/v1
Autor:
Chi Wai, Wong, Penelope Mei Yu, Or, Yubing, Wang, Lisha, Li, Jing, Li, Mingfei, Yan, Ye, Cao, Ho Ming, Luk, Tony Ming For, Tong, Nick R, Leslie, Ivan Fai-Man, Lo, Kwong Wai, Choy, Andrew Man Lok, Chan
Publikováno v:
Autism Research
PTEN is a tumor suppressor gene inactivated in over 30% of human cancers. It encodes a lipid phosphatase that serves as a gatekeeper of the phosphoinositide 3‐kinase signaling pathway. Germline mutation frequently occurs in this gene in patients di