Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andrew Mahan"'
Autor:
Lauren E. Boucher, Elisabeth Geyer Prinslow, Michael Feldkamp, Fang Yi, Rupesh Nanjunda, Sheng-Jiun Wu, Tun Liu, Eilyn R. Lacy, Steven Jacobs, Natalia Kozlyuk, Brian Del Rosario, Bingyuan Wu, Patricia Aquino, Robert C. Davidson, Samantha Heyne, Nicholas Mazzanti, James Testa, Michael D. Diem, Elsa Gorre, Andrew Mahan, Hirsh Nanda, Harsha P. Gunawardena, Alexis Gervais, Anthony A. Armstrong, Alexey Teplyakov, Chichi Huang, Adam Zwolak, Partha Chowdhury, Wan Cheung Cheung, Jinquan Luo
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTSingle-chain fragment variable (scFv) domains play an important role in antibody-based therapeutic modalities, such as bispecifics, multispecifics and chimeric antigen receptor T cells or natural killer cells. However, scFv domains exhibit lo
Externí odkaz:
https://doaj.org/article/07a49e5767d741f0bc24b50e3af689e1
Autor:
Trina Mouchahoir, John E. Schiel, Rich Rogers, Alan Heckert, Benjamin J. Place, Aaron Ammerman, Xiaoxiao Li, Tom Robinson, Brian Schmidt, Chris M. Chumsae, Xinbi Li, Anton V. Manuilov, Bo Yan, Gregory O. Staples, Da Ren, Alexander J. Veach, Dongdong Wang, Wael Yared, Zoran Sosic, Yan Wang, Li Zang, Anthony M. Leone, Peiran Liu, Richard Ludwig, Li Tao, Wei Wu, Ahmet Cansizoglu, Andrew Hanneman, Greg W. Adams, Irina Perdivara, Hunter Walker, Margo Wilson, Arnd Brandenburg, Nick DeGraan-Weber, Stefano Gotta, Joe Shambaugh, Melissa Alvarez, X. Christopher Yu, Li Cao, Chun Shao, Andrew Mahan, Hirsh Nanda, Kristen Nields, Nancy Nightlinger, Ben Niu, Jihong Wang, Wei Xu, Gabriella Leo, Nunzio Sepe, Yan-Hui Liu, Bhumit A. Patel, Douglas Richardson, Yi Wang, Daniela Tizabi, Oleg V. Borisov, Yali Lu, Ernest L. Maynard, Albrecht Gruhler, Kim F. Haselmann, Thomas N. Krogh, Carsten P. Sönksen, Simon Letarte, Sean Shen, Kristin Boggio, Keith Johnson, Wenqin Ni, Himakshi Patel, David Ripley, Jason C. Rouse, Ying Zhang, Carly Daniels, Andrew Dawdy, Olga Friese, Thomas W. Powers, Justin B. Sperry, Josh Woods, Eric Carlson, K. Ilker Sen, St John Skilton, Michelle Busch, Anders Lund, Martha Stapels, Xu Guo, Sibylle Heidelberger, Harini Kaluarachchi, Sean McCarthy, John Kim, Jing Zhen, Ying Zhou, Sarah Rogstad, Xiaoshi Wang, Jing Fang, Weibin Chen, Ying Qing Yu, John G. Hoogerheide, Rebecca Scott, Hua Yuan
Publikováno v:
Journal of the American Society for Mass Spectrometry. 33:1659-1677
The multi-attribute method (MAM) was conceived as a single assay to potentially replace multiple single-attribute assays that have long been used in process development and quality control (QC) for protein therapeutics. MAM is rooted in traditional p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fbb68de4c53ee4678b9e74066d51588
https://doi.org/10.1021/jasms.2c00129
https://doi.org/10.1021/jasms.2c00129
Autor:
Irina Perdivara, Ben Niu, Kim F. Haselmann, St John Skilton, Anthony Leone, Gregory O. Staples, Carsten P. Sønksen, Helena Maria Barysz, Andrew Hanneman, Chun Shao, Rebecca Scott, Anders Lund, Carly Daniels, Michael Jahn, Da Ren, Nunzio Sepe, K. Ilker Sen, Zoran Sosic, David Ripley, Jing Zhen, Margo Wilson, Melissa Alvarez, John G Hoogerheide, Xinbi Li, Harini Kaluarachchi, Josh Woods, Wenqin Ni, Albrecht Gruhler, Keith A. Johnson, Arnd Brandenburg, Kristen Nields, Michelle Busch, Douglas D. Richardson, Yan Wang, Ahmet Cansizoglu, Xiaoxiao Li, Greg W Adams, Simon Letarte, Joe Shambaugh, Hua Yuan, Trina Mouchahoir, Tom Robinson, Xiaoshi Wang, Nancy S. Nightlinger, Alexander Julian Veach, Chris Chumsae, Eric Carlson, Dongdong Wang, Sean Shen, Jing Fang, Wei Wu, Stefano Gotta, Justin B. Sperry, Hirsh Nanda, X. Christopher Yu, Sibylle Heidelberger, Bhumit A. Patel, Jihong Wang, Sean McCarthy, Himakshi Patel, Thomas N. Krogh, Hunter Walker, Olga V. Friese, Daniela Tizabi, Yali Lu, Kristin Boggio, Ernest L. Maynard, Rich Rogers, Ying Zhou, Nick DeGraan-Weber, John E. Schiel, Weibin Chen, Jason C. Rouse, Li Tao, Thomas W. Powers, John Kim, Xu Guo, Bo Yan, Gabriella Leo, Ying Zhang, Oleg V. Borisov, Ying Qing Yu, Martha Stapels, Wael Yared, Yan-Hui Liu, Alan Heckert, Sarah Rogstad, Li Zang, Aaron Ammerman, Li Cao, Benjamin J. Place, Richard Ludwig, Anton V. Manuilov, Andrew Mahan, Andrew Dawdy, Yi Wang, Brian Schmidt, Peiran Liu
Publikováno v:
Journal of the American Society for Mass Spectrometry. 32:913-928
The Multi-Attribute Method (MAM) Consortium was initially formed as a venue to harmonize best practices, share experiences, and generate innovative methodologies to facilitate widespread integration of the MAM platform, which is an emerging ultra-hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4baf4a0ab2df01bdb011465e0f168239
https://doi.org/10.1021/jasms.0c00415
https://doi.org/10.1021/jasms.0c00415
Autor:
Santosh V. Thakkar, Danika Rodrigues, Bo Zhai, Dwaine Banton, Sandeep Somani, Alex Javidi, Andrew Mahan, Stuart Ember, Dominick DeGrazio, Subinay Ganguly, Ketan Amin, Hirsh Nanda
Publikováno v:
Journal of pharmaceutical sciences.
The rational design and selection of formulation composition to meet molecule-specific and product-specific needs are critical for biotherapeutics development to ensure physical and chemical stability. This work, based on three antibody-based (mAb) p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82868a3378cdaad24636527f8bb1c1cf
https://pubmed.ncbi.nlm.nih.gov/36130676
https://pubmed.ncbi.nlm.nih.gov/36130676
Publikováno v:
Structure
Structure (London, England : 1993), vol 27, iss 8
Structure (London, England : 1993), vol 27, iss 8
Summary The interleukin 1 (IL-1) receptor family, whose members contain three immunoglobulin-like domains (D1–D3) in the extracellular region, is responsible for transmitting pleiotropic signals of IL-1 cytokines. The inter-domain flexibility of IL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add8a3486c30222fa78c87c76233467f
https://pubmed.ncbi.nlm.nih.gov/31257107
https://pubmed.ncbi.nlm.nih.gov/31257107
Autor:
John E. Schiel, Darryl L. Davis, Oleg V. Borisov, Trina Formolo, Mellisa Ly, Michaella Levy, Lisa Kilpatrick, Scott Lute, Karen Phinney, Lisa Marzilli, Kurt Brorson, Michael Boyne, Darryl Davis, John Schiel, Melissa Alvarez, James A. Carroll, Paul W. Brown, Wenzhou Li, James L. Kerwin, Andrew Mahan, Sabrina A. Benchaar, Justin M. Prien, Henning Stöckmann, Simone Albrecht, Silvia M. Martin, Matthew Varatta, Marsha Furtado, Stephen Hosselet, Meiyao Wang, Pauline M. Rudd, David A. Michels, Anna Y. Ip, Thomas M. Dillon, Brittany Chavez, Ken M. Prentice, Lowell J. Brady, Karen J. Miller, Yatin Gokarn, Sanjeev Agarwal, Kelly Arthur, Alexander Bepperling, Eric S. Day, Dana Filoti, Daniel G. Greene, David Hayes, Rachel Kroe-Barrett, Thomas Laue, Jasper Lin, Brian McGarry, Vladimir Razinkov, Sanjaya Singh, Rosalynn Taing, Sathyadevi Venkataramani, William Weiss, Danlin Yang, Isidro E. Zarraga, Dorina Saro, Audrey Baker, Robert Hepler, Stacey Spencer, Rick Bruce, Steven LaBrenz, Mark Chiu, Steven E. Lang, Dean C. Ripple, Linda O. Narhi, Kesh Prakash, Weibin Che
Publikováno v:
Remesh, SG; Armstrong, AA; Mahan, AD; Luo, J; & Hammel, M. (2018). Conformational Plasticity of the Immunoglobulin Fc Domain in Solution. Structure, 26(7), 1007-1014.e2. doi: 10.1016/j.str.2018.03.017. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/21q3d6wg
Structure (London, England : 1993), vol 26, iss 7
Structure (London, England : 1993), vol 26, iss 7
© 2018 The Author(s) Fragment crystallizable (Fc) region of immunoglobulin G (IgG) antibody binds to specific Fc receptors (FcγRs) to control antibody effector functions. Currently, engineered specific Fc-FcγR interactions are validated with a sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f11f78ea6c437d2dbb861ad686345808
https://doi.org/10.1016/j.str.2018.03.017
https://doi.org/10.1016/j.str.2018.03.017
Autor:
Bruce E. Maryanoff, Harold R. Almond, Cynthia A. Maryanoff, Andrew Mahan, Mabel Alamino Cejas, Cailin Chen, Karin M. Balss, William A. Kinney, Jeremy G. Vinter, Eilyn Lacy, Michael Breslav, Ute Schmidt
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 105(25)
Collagens are integral structural proteins in animal tissues and play key functional roles in cellular modulation. We sought to discover collagen model peptides (CMPs) that would form triple helices and self-assemble into supramolecular fibrils exhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::725e40ac1bed9450de302b1bcfdaf007
https://pubmed.ncbi.nlm.nih.gov/18559857
https://pubmed.ncbi.nlm.nih.gov/18559857