A Multicenter Evaluation of the Seraph 100 Microbind Affinity Blood Filter for the Treatment of Severe COVID-19

Autor: Stephen A. Chitty, MD, Sarah Mobbs, FNP-BC, Brian S. Rifkin, MD, Steven W. Stogner, MD, Michael S. Lewis, MD, Jaime Betancourt, MD, Jeffrey DellaVolpe, MD, Fadi Abouzahr, MD, Andrew M. Wilhelm, DO, Harold M. Szerlip, MD, Amay Parikh, MD, Robert M. Gaeta, DO, Ian Rivera, MD, Caroline Park, MD, MPH, Benjamin Levi, MD, George L. Anesi, MD, MSCE, MBE, Karl C. Alcover, PhD, Thomas B. Arnold, BA, Jeffrey T. Howard, PhD, Kumar Sharma, MD, Kathleen P. Pratt, PhD, Ian J. Stewart, MD, Kevin K. Chung, MD, for the PURIFY Investigators, Amay Parikh, Sarah Guyler, Harold Szerlip, Giselle Carino, Tanqunisha Coleman, Robert J. Walter, Mai Nguyen, Robert Gaeta, Ian M. Rivera, Ferdinand Bacomo, Sean C. Reilly, Susan D. Rogers, Delia Marshall, Melba Francis, Sholanda Henderson, Bob Ward, Keith McCrea, Erdie de Peralta, Lakhmir S. Chawla, Andrea Worsham, Michael Benjamin, Brian Rifkin, Steven Stogner, Steve Farrell, Karen Brooks, Maria Voelkel, Sophie Haralson, Marianne Spevak, Daniell Clark, Laura Osgood, Qianru Wu, Kevin Grant, Rittal Mehta, Jeffrey Dellavolpe, Fadi Abouzahr, Mohammed Ahmed, Ginger Dowell, Stephen Amerson, Stephen Chitty, Srah Mobbs, Gwen Gratto-Cox, Christy Jordan, George Peoples, Dan Hargrove, Karen Arrington, Lauren Zahra, Jessica Raley, Katie Lyon, Rachel Macomber, Ashlee Richie, Tineka Brown, Laura Richie, Susan Hargrove, Emily Scribe, Steven White, Kevin Chung, Ian Stewart, Kathleen Pratt, Karl Alcover, Thomas B. Arnold, Lauren Walker, Amy Laczek, Breandan Sullivan, Nick Naughton, Sabrina Espinoza, Vikhyat Bebarta, Adit Ginde, Anip Bansal, Ilona Dewald, Isidro Susano Basilio, Andrew Wilhelm, Delia Owens, George L. Anesi, Kumar Sharma, Subrata Debnath, Sean P. Barnett, Nicholas S. Niazi, Jeffrey Howard, Benjamin Levi, Caroline Park, Tamim Hamdi, Peiman Lahsaei, Nilum Rajora, Christopher Choi, Andriy I Batchinsky, Michael Lewis, Jaime Betancourt, Nancy Mohler, Natalia Dudek, Jasmine Bagnas, James Oliver, Stephen Olson, Jenny Nguyen

Publikováno v: Critical Care Explorations, Vol 4, Iss 4, p e0662 (2022)

OBJECTIVES:. The Seraph100 Microbind Affinity Blood Filter (Seraph 100) (ExThera Medical, Martinez, CA) is an extracorporeal therapy that can remove pathogens from blood, including severe acute respiratory syndrome coronavirus 2. The aim of this stud

Externí odkaz: https://doaj.org/article/3f6a8767ddbf40e0969d51375bf485d0

A Pharmacologic Approach to Acquired Cystic Fibrosis Transmembrane Conductance Regulator Dysfunction in Smoking Related Lung Disease

Autor: Yao Li, Suresh Shastry, Kyle Backer, Clifford A. Courville, Elina Levin, Suzanne Byan-Parker, Eric J. Sorscher, Mark T. Dransfield, Peter A. Sloane, Li Ping Tang, Andrew M. Wilhelm, Steven M. Rowe, S. Vamsee Raju, William E. Grizzle, Marina Mazur

Publikováno v: PLoS ONE
PLoS ONE, Vol 7, Iss 6, p e39809 (2012)

Background Mucus stasis in chronic obstructive pulmonary disease (COPD) is a significant contributor to morbidity and mortality. Potentiators of cystic fibrosis transmembrane conductance regulator (CFTR) activity pharmacologically enhance CFTR functi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c37864a40d4e50b6cedfccba00d41fb
http://europepmc.org/articles/PMC3387224

Cystic Fibrosis Transmembrane Conductance Regulator Function In Chronic Obstructive Pulmonary Disease

Autor: Navnit Mehta, Mark T. Dransfield, Andrew M. Wilhelm, Steve Rowe

Publikováno v: B42. COPD PATHOGENESIS: CELLULAR EXPRESSION AND PROTEIN RESPONSES.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::23d72d1d82cd6dcc8bb55831c7b81c9f
https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a3021

Reduced Cystic Fibrosis Transmembrane Conductance Regulator Function In Smoke Induced Chronic Obstructive Pulmonary Disease

Autor: Heather Young, Li Ping Tang, Mark T. Dransfield, Suresh Shastry, Gina Sabbatini, Cliff Courville, Andrew M. Wilhelm, Steven M. Rowe, Ginger Reeves

Publikováno v: B38. CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATHOGENESIS II.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::025decb1e53e8dcb7a33db2b7d321c4f
https://doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a2920