Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Andrew M. Garrett"'
Autor:
Michael J. Molumby, Rachel M. Anderson, Dillan J. Newbold, Norah K. Koblesky, Andrew M. Garrett, Dietmar Schreiner, Jason J. Radley, Joshua A. Weiner
Publikováno v:
Cell Reports, Vol 18, Iss 11, Pp 2702-2714 (2017)
The 22 γ-Protocadherin (γ-Pcdh) cell adhesion molecules are critical for the elaboration of complex dendritic arbors in the cerebral cortex. Here, we provide evidence that the γ-Pcdhs negatively regulate synapse development by inhibiting the posts
Externí odkaz:
https://doaj.org/article/efd28dc1daf948f7a9c622d38a4988a0
Autor:
Shan Meltzer, Katelyn C. Boulanger, Anda M. Chirila, Emmanuella Osei-Asante, Michelle DeLisle, Qiyu Zhang, Brian T. Kalish, Aniqa Tasnim, Erica L. Huey, Leah C. Fuller, Erin K. Flaherty, Tom Maniatis, Andrew M. Garrett, Joshua A. Weiner, David D. Ginty
Publikováno v:
Neuron.
Autor:
Shan Meltzer, Katelyn Comeau, Anda Chirila, Emmanuella Osei-Asante, Michelle DeLisle, Qiyu Zhang, Brian T. Kalish, Aniqa Tasnim, Erica Huey, Leah C. Fuller, Erin K. Flaherty, Julie L. Lefebvre, Tom Maniatis, Andrew M. Garrett, Joshua A. Weiner, David D. Ginty
SummaryLight touch sensation begins with activation of low-threshold mechanoreceptor (LTMR) endings in the skin and propagation of their signals to the spinal cord and brainstem. We found that the clustered protocadherin gamma (Pcdhg) gene locus, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e5bcc3e8fc24b75ff5077f527493f58
https://doi.org/10.1101/2022.05.25.493080
https://doi.org/10.1101/2022.05.25.493080
Autor:
David M. Steffen, Camille M. Hanes, Kar Men Mah, Paula Valiño Ramos, Peter J. Bosch, Dalton C. Hinz, Jason J. Radley, Robert W. Burgess, Andrew M. Garrett, Joshua A. Weiner
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience.
The establishment of a functional cerebral cortex depends on the proper execution of multiple developmental steps, culminating in dendritic and axonal outgrowth and the formation and maturation of synaptic connections. Dysregulation of these processe
Autor:
Cathy M. McLeod, Andrew M. Garrett
Publikováno v:
Current Topics in Developmental Biology ISBN: 9780128171318
Curr Top Dev Biol
Curr Top Dev Biol
Since their first description, the clustered protocadherins (cPcdhs) have sparked interest for their potential to generate diverse cell-surface recognition cues and their widespread expression in the nervous system. Through the use of mouse models, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0fbfe9b6c685bdbfc4478a8a5c33dbb
https://doi.org/10.1016/bs.ctdb.2021.12.006
https://doi.org/10.1016/bs.ctdb.2021.12.006
Publikováno v:
eLife, Vol 5 (2016)
Different types of neurons in the retina are organized vertically into layers and horizontally in a mosaic pattern that helps ensure proper neural network formation and information processing throughout the visual field. The vertebrate Dscams (DSCAM
Externí odkaz:
https://doaj.org/article/7d9c8033641341c7a4d94418307f81e3
Autor:
Andrew M Garrett, Robert W Burgess
Publikováno v:
eLife, Vol 4 (2015)
Proteins called gamma-protocadherins are essential for the establishment of working circuits of neurons in the retina.
Externí odkaz:
https://doaj.org/article/846ebec672294cd3884348227d593305
Publikováno v:
Progress in Retinal and Eye Research. 90:101038
Cadherins are a superfamily of calcium-dependent intercellular adhesion molecules that are widely expressed in living tissues. Within the retina and retinal pigment epithelium (RPE), cadherins contribute to tissue morphogenesis, neural circuit format
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 5 (2012)
Many of the models of neurodevelopmental processes such as cell migration, axon outgrowth, and dendrite arborization involve cell adhesion and chemoattraction as critical physical or mechanical aspects of the mechanism. However, the prevention of adh
Externí odkaz:
https://doaj.org/article/7544f0efa1ec4cf7962f159b0e5e8d4f