Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Andrew M. Boal"'
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionIdentification of early adaptive and maladaptive neuronal stress responses is an important step in developing targeted neuroprotective therapies for degenerative disease. In glaucoma, retinal ganglion cells (RGCs) and their axons undergo
Externí odkaz:
https://doaj.org/article/6b398316a73042a495ab710828d24ef4
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Neuronal type-specific physiologic heterogeneity can be driven by both extrinsic and intrinsic mechanisms. In retinal ganglion cells (RGCs), which carry visual information from the retina to central targets, evidence suggests intrinsic properties sha
Externí odkaz:
https://doaj.org/article/d3d7712c5f1048b58ecb99152f693a30
Autor:
Sarah Naguib, Carlisle R. DeJulius, Jon R. Backstrom, Ameer A. Haider, John M. Ang, Andrew M. Boal, David J. Calkins, Craig L. Duvall, Tonia S. Rex
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 556 (2023)
Erythropoietin (EPO) is neuroprotective in multiple models of neurodegenerative diseases, including glaucoma. EPO-R76E retains the neuroprotective effects of EPO but diminishes the effects on hematocrit. Treatment with EPO-R76E in a glaucoma model in
Externí odkaz:
https://doaj.org/article/f425def142764bd78d4e216706b866ad
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2021)
Early progression in neurodegenerative disease involves challenges to homeostatic processes, including those controlling axonal excitability and dendritic organization. In glaucoma, the leading cause of irreversible blindness, stress from intraocular
Externí odkaz:
https://doaj.org/article/98328bee1f684629a8b9579b5a1eb8ab
Autor:
Joseph M. Holden, Sara Al Hussein Al Awamlh, Louis-Philippe Croteau, Andrew M. Boal, Tonia S. Rex, Michael L. Risner, David J. Calkins, Lauren K. Wareham
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 3066 (2022)
The nitric oxide–guanylyl cyclase-1–cyclic guanylate monophosphate (NO–GC-1–cGMP) pathway is integral to the control of vascular tone and morphology. Mice lacking the alpha catalytic domain of guanylate cyclase (GC1−/−) develop retinal ga
Externí odkaz:
https://doaj.org/article/f267cc491cb14b9ba48426fddd832d27
Publikováno v:
Cells, Vol 10, Iss 6, p 1368 (2021)
Astrocytes are intimately involved in the response to neurodegenerative stress and have become an attractive target for the development of neuroprotective therapies. However, studies often focus on astrocytes as single-cell units. Astrocytes are dens
Externí odkaz:
https://doaj.org/article/9df58cb78f554b3fbed5e5dc7d68aba9
Autor:
Nolan R. McGrady, Andrew M. Boal, Michael L. Risner, Magali Taiel, Jose A. Sahel, David J. Calkins
Publikováno v:
Molecular Therapy.
Autor:
Andrew M. Boal, Nolan R. McGrady, Xitiz Chamling, Bhanu S. Kagitapalli, Donald J. Zack, David J. Calkins, Michael L. Risner
Publikováno v:
Translational Vision Science & Technology. 12:1
Autor:
Nolan R McGrady, Joseph M Holden, Marcio Ribeiro, Andrew M Boal, Michael L Risner, David J Calkins
Publikováno v:
Brain communications. 4(5)
Optic neuropathies are characterized by degeneration of retinal ganglion cell axonal projections to the brain, including acute conditions like optic nerve trauma and progressive conditions such as glaucoma. Despite different aetiologies, retinal gang
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2021)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
Early progression in neurodegenerative disease involves challenges to homeostatic processes, including those controlling axonal excitability and dendritic organization. In glaucoma, the leading cause of irreversible blindness, stress from intraocular