Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Andrew M Lynn"'
Autor:
Sonam Kumari, Mohit Kumar, Nitesh Kumar Khandelwal, Priya Kumari, Mahendra Varma, Poonam Vishwakarma, Garima Shahi, Suman Sharma, Andrew M Lynn, Rajendra Prasad, Naseem A Gaur
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202993 (2018)
ATP-binding cassette (ABC) is one of the two major superfamilies of transporters present across the evolutionary scale. ABC superfamily members came to prominence due to their ability to extrude broad spectrum of substrates and to confer multi drug r
Externí odkaz:
https://doaj.org/article/ad732fe984bf42029de54364917c6ba2
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11041 (2010)
By employing information theoretic measures, this study presents a structure and functional analysis of a multidrug-proton antiporter Mdr1p of Candida albicans. Since CaMdr1p belongs to drug-proton antiporter (DHA1) family of Major Facilitator Superf
Externí odkaz:
https://doaj.org/article/8aa941e7e78f4445987192f7d2a5ab11
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 12, p e1000624 (2009)
CaMdr1p is a multidrug MFS transporter of pathogenic Candida albicans. An over-expression of the gene encoding this protein is linked to clinically encountered azole resistance. In-depth knowledge of the structure and function of CaMdr1p is necessary
Externí odkaz:
https://doaj.org/article/426e93bf11a94f42a1992287ec3113c3
Autor:
Harbinder Kaur, Andrew M. Lynn
Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
Cytokinesis is an essential process in bacterial cell division, and it involves more than 25 essential/non-essential cell division proteins that form a protein complex known as a divisome. Central to the divisome are the proteins FtsB and FtsL bindin
Externí odkaz:
https://doaj.org/article/5442319a34d24660a8d7eefacb1c407b
Autor:
Ruiting Li, Ruhar Singh, Tara Kashav, ChunMin Yang, Ravi Datta Sharma, Andrew M. Lynn, Rajendra Prasad, Amresh Prakash, Vijay Kumar
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
TDP-43 proteinopathies is a disease hallmark that characterizes amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). The N-terminal domain of TDP-43 (NTD) is important to both TDP-43 physiology and TDP-43 proteinopathy. H
Externí odkaz:
https://doaj.org/article/5bc1704520564d32b0c17d9e3a8c39a6
Autor:
Rosy Khatoon, Suman Sharma, Poonam Vishwakarma, Amandeep Saini, Parth Aggarwal, Andrew M. Lynn, Amresh Prakash, Rajendra Prasad, Atanu Banerjee
Publikováno v:
Applied Microbiology and Biotechnology. 106:7085-7097
The last decade has witnessed the rise of an extremely threatening healthcare-associated multidrug-resistant non-albicans Candida (NAC) species, Candida auris. Since besides target alterations, efflux mechanisms contribute maximally to antifungal res
Publikováno v:
Applied Microbiology and Biotechnology. 106:4223-4235
The peptide transport (PTR) or proton-dependent oligopeptide transporter (POT) family exploits the inwardly directed proton motive force to facilitate the cellular uptake of di/tripeptides. Interestingly, some representatives are also shown to import
Autor:
Mohd Wasi, Nitesh Kumar Khandelwal, Alexander J. Moorhouse, Remya Nair, Poonam Vishwakarma, Gustavo Bravo Ruiz, Zoe K. Ross, Alexander Lorenz, Shivaprakash M. Rudramurthy, Arunaloke Chakrabarti, Andrew M. Lynn, Alok K. Mondal, Neil A. R. Gow, Rajendra Prasad
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
ATP-binding cassette (ABC) superfamily members have a key role as nutrient importers and exporters in bacteria. However, their role as drug exporters in eukaryotes brought this superfamily member to even greater prominence. The capacity of ABC transp
Externí odkaz:
https://doaj.org/article/3c8c88fc2ef04f649c4f31dc3da61b1c
Autor:
F. Aura Kullmann, Bronagh M. McDonnell, Amanda S. Wolf-Johnston, Andrew M. Lynn, Daniel Giglio, Samuel E. Getchell, Wily G. Ruiz, Irina V. Zabbarova, Youko Ikeda, Anthony J. Kanai, James R. Roppolo, Sheldon I. Bastacky, Gerard Apodaca, C. A. Tony Buffington, Lori A. Birder
Publikováno v:
Frontiers in Systems Neuroscience, Vol 12 (2018)
Externí odkaz:
https://doaj.org/article/a61996645ad24d2ea2815821f5fe8115
Autor:
F. Aura Kullmann, Bronagh M. McDonnell, Amanda S. Wolf-Johnston, Andrew M. Lynn, Daniel Giglio, Samuel E. Getchell, Wily G. Ruiz, Irina V. Zabbarova, Youko Ikeda, Anthony J. Kanai, James R. Roppolo, Sheldon I. Bastacky, Gerard Apodaca, C. A. Tony Buffington, Lori A. Birder
Publikováno v:
Frontiers in Systems Neuroscience, Vol 12 (2018)
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a debilitating chronic disease of unknown etiology. A naturally occurring disease termed feline interstitial cystitis (FIC) reproduces many features of IC/BPS patients. To gain insights into mec
Externí odkaz:
https://doaj.org/article/24038923312a41c28a01174ee0918ae4