Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Andrew M Kaz"'
Autor:
Kit Curtius, Chao-Jen Wong, William D Hazelton, Andrew M Kaz, Amitabh Chak, Joseph E Willis, William M Grady, E Georg Luebeck
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 5, p e1004919 (2016)
Biomarkers that drift differentially with age between normal and premalignant tissues, such as Barrett's esophagus (BE), have the potential to improve the assessment of a patient's cancer risk by providing quantitative information about how long a pa
Externí odkaz:
https://doaj.org/article/45b4777556654b089d73fc2f1d9aabb9
Autor:
Yanxin Luo, Andrew M Kaz, Samornmas Kanngurn, Piri Welsch, Shelli M Morris, Jianping Wang, James D Lutterbaugh, Sanford D Markowitz, William M Grady
Publikováno v:
PLoS Genetics, Vol 9, Iss 7, p e1003552 (2013)
NTRK3 is a member of the neurotrophin receptor family and regulates cell survival. It appears to be a dependence receptor, and thus has the potential to act as an oncogene or as a tumor suppressor gene. NTRK3 is a receptor for NT-3 and when bound to
Externí odkaz:
https://doaj.org/article/b0e3aaf7df6f4288b736c8dc7a308ba5
Autor:
William M. Grady, John M. Inadomi, Yanxin Luo, Andrew M. Kaz, Maria Westerhoff, Polly A. Newcomb, Cornelia M. Ulrich, Christopher I. Li, Paul D. Lampe, Wynn Burke, Kelly T. Carter, Ming Yu, Sean K. Maden, Kit Curtius, William D. Hazelton, Georg E. Luebeck
This file provides a list of drift-related CGI-gene pairs for which methylation is significantly correlated with gene expression (q-value ) in left colon (including rectum) and right colon.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f5289f92cf5546594bcfb2716dc9f86
https://doi.org/10.1158/0008-5472.22422023.v1
https://doi.org/10.1158/0008-5472.22422023.v1
Autor:
Yanxin Luo, Jianping Wang, William M. Grady, Andrew M. Kaz, Guangwen Cao, Meijin Huang, Shaoyong Peng, Baoyuan Huang, Xiaolin Wang, Du Cai, Huichuan Yu, Liangliang Bai, Yingjie Li
Supplemental Figures 1-10 and Reagent table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::886608fc41bed92f78da0fe617cd870e
https://doi.org/10.1158/0008-5472.22426489
https://doi.org/10.1158/0008-5472.22426489
Autor:
Yanxin Luo, Jianping Wang, William M. Grady, Andrew M. Kaz, Guangwen Cao, Meijin Huang, Shaoyong Peng, Baoyuan Huang, Xiaolin Wang, Du Cai, Huichuan Yu, Liangliang Bai, Yingjie Li
DNA methylation contributes to malignant transformation, but little is known about how the methylation drives colorectal cancer evolution at the early stages. Here we identify aberrant INA (α-internexin) gene methylation in colon adenoma and adenoca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad504cae5f054234e66147b5527d6bf4
https://doi.org/10.1158/0008-5472.c.6512353
https://doi.org/10.1158/0008-5472.c.6512353
Autor:
William M. Grady, John M. Inadomi, Yanxin Luo, Andrew M. Kaz, Maria Westerhoff, Polly A. Newcomb, Cornelia M. Ulrich, Christopher I. Li, Paul D. Lampe, Wynn Burke, Kelly T. Carter, Ming Yu, Sean K. Maden, Kit Curtius, William D. Hazelton, Georg E. Luebeck
Many normal tissues undergo age-related drift in DNA methylation, providing a quantitative measure of tissue age. Here, we identify and validate 781 CpG islands (CGI) that undergo significant methylomic drift in 232 normal colorectal tissues and show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfe81d072d3b4d98214b6bb6be3dc85d
https://doi.org/10.1158/0008-5472.c.6511112.v1
https://doi.org/10.1158/0008-5472.c.6511112.v1
Autor:
Yanxin Luo, Jianping Wang, William M. Grady, Andrew M. Kaz, Guangwen Cao, Meijin Huang, Shaoyong Peng, Baoyuan Huang, Xiaolin Wang, Du Cai, Huichuan Yu, Liangliang Bai, Yingjie Li
Table S1. The distribution and calculated pI of peptides in the peptide arrays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382a655cec386e7c1624caf83d95419f
https://doi.org/10.1158/0008-5472.22426486.v1
https://doi.org/10.1158/0008-5472.22426486.v1
Autor:
William M. Grady, Jill S. Barnholtz-Sloan, Yanwen Chen, Nicholas J. Shaheen, Chao-Jen Wong, Maria Westerhoff, Sharmila Anandabapasathy, Dean E. Brenner, Sanford D. Markowitz, Helen R. Moinova, Joseph E. Willis, Apoorva Chandar, Amitabh Chak, Kelly T. Carter, Shelli M. Morris, Andrew M. Kaz, Rachele M. O'Leary, Ming Yu
Supplemental Figure S1: Assessment of precision of pyrosequencing assay for methylated B3GAT2 and ZNF793. Supplemental Figure S2: Correlation of pyrosequencing results with HM450 array beta values.Supplemental Figure S3: Methylation status of B3GAT2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4d95f1274e095f79e0bb852c8f8a50
https://doi.org/10.1158/1055-9965.22437193
https://doi.org/10.1158/1055-9965.22437193
Autor:
William M. Grady, John M. Inadomi, Yanxin Luo, Andrew M. Kaz, Maria Westerhoff, Polly A. Newcomb, Cornelia M. Ulrich, Christopher I. Li, Paul D. Lampe, Wynn Burke, Kelly T. Carter, Ming Yu, Sean K. Maden, Kit Curtius, William D. Hazelton, Georg E. Luebeck
Derivation of adenoma to carcinoma sojourn times, with table S1 showing estimated methylation drift rate parameters and table S2 showing estimated sojourn times for three tissue age models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387086829e2f16edc62f32ab39e210d5
https://doi.org/10.1158/0008-5472.22422017.v1
https://doi.org/10.1158/0008-5472.22422017.v1
Autor:
William M. Grady, Jill S. Barnholtz-Sloan, Yanwen Chen, Nicholas J. Shaheen, Chao-Jen Wong, Maria Westerhoff, Sharmila Anandabapasathy, Dean E. Brenner, Sanford D. Markowitz, Helen R. Moinova, Joseph E. Willis, Apoorva Chandar, Amitabh Chak, Kelly T. Carter, Shelli M. Morris, Andrew M. Kaz, Rachele M. O'Leary, Ming Yu
Supplemental Table S2: Methylation levels for B3GAT2 and ZNF793 from Human Methylation450 arrays.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d589175f20dad46f6d562232a6a2c92
https://doi.org/10.1158/1055-9965.22437187
https://doi.org/10.1158/1055-9965.22437187