Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Andrew M Collins"'
Autor:
Aviv Omer, Ayelet Peres, Oscar L Rodriguez, Corey T Watson, William Lees, Pazit Polak, Andrew M Collins, Gur Yaari
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-19 (2022)
Abstract Background T and B cell receptor (TCR, BCR) repertoires constitute the foundation of adaptive immunity. Adaptive immune receptor repertoire sequencing (AIRR-seq) is a common approach to study immune system dynamics. Understanding the genetic
Externí odkaz:
https://doaj.org/article/3c50bc1277d7488e97ea543c541518b1
Autor:
Yan Wang, Katherine J L Jackson, Janet Davies, Zhiliang Chen, Bruno A Gaeta, Janet Rimmer, William A Sewell, Andrew M Collins
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89730 (2014)
Antigen selection of B cells within the germinal center reaction generally leads to the accumulation of replacement mutations in the complementarity-determining regions (CDRs) of immunoglobulin genes. Studies of mutations in IgE-associated VDJ gene s
Externí odkaz:
https://doaj.org/article/a1f0953652fc401faf7b688831877283
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
Both the B cell receptor (BCR) and the T cell receptor (TCR) repertoires are generated through essentially identical processes of V(D)J recombination, exonuclease trimming of germline genes and the random addition of non-template encoded nucleotides.
Externí odkaz:
https://doaj.org/article/409705b8d1934e879bac3c3f93796f48
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
The diversity of the human antibody repertoire that is generated by V(D)J gene rearrangement is extended by nine constant region genes that give antibodies their complex array of effector functions. The application of high throughput sequencing to th
Externí odkaz:
https://doaj.org/article/d2e75bcd7fab42d3a7e0e79a7eeb70c3
Autor:
Andrew M. Collins, Mats Ohlin, Martin Corcoran, James M. Heather, Duncan Ralph, Mansun Law, Jesus Martínez-Barnetche, Jian Ye, Eve Richardson, William S. Gibson, Oscar L. Rodriguez, Ayelet Peres, Gur Yaari, Corey T. Watson, William D. Lees
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
IntroductionAnalysis of an individual’s immunoglobulin (IG) gene repertoire requires the use of high-quality germline gene reference sets. When sets only contain alleles supported by strong evidence, AIRR sequencing (AIRR-seq) data analysis is more
Externí odkaz:
https://doaj.org/article/aa654cd36aa94db1a0e3b47ed8578d9f
Autor:
Katherine J. L. Jackson, Justin T. Kos, William Lees, William S. Gibson, Melissa Laird Smith, Ayelet Peres, Gur Yaari, Martin Corcoran, Christian E. Busse, Mats Ohlin, Corey T. Watson, Andrew M. Collins
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The immunoglobulin genes of inbred mouse strains that are commonly used in models of antibody-mediated human diseases are poorly characterized. This compromises data analysis. To infer the immunoglobulin genes of BALB/c mice, we used long-read SMRT s
Externí odkaz:
https://doaj.org/article/622ded152c8546b1835641d908b2d213
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/f6613a724a25481ea976b05351059f77
Autor:
Ayelet Peres, William D. Lees, Oscar L. Rodriguez, Noah Y. Lee, Pazit Polak, Ronen Hope, Meirav Kedmi, Andrew M. Collins, Mats Ohlin, Steven H. Kleinstein, Corey T Watson, Gur Yaari
In adaptive immune receptor repertoire analysis, determining the germline variable (V) allele associated with each T- and B-cell receptor sequence is a crucial step. This process is highly impacted by allele annotations. Aligning sequences, assigning
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84f48ab09732df7e614d75bacdf548eb
https://doi.org/10.1101/2022.12.26.521922
https://doi.org/10.1101/2022.12.26.521922
Autor:
William D. Lees, Scott Christley, Ayelet Peres, Justin T. Kos, Brian Corrie, Duncan Ralph, Felix Breden, Lindsay G. Cowell, Gur Yaari, Martin Corcoran, Gunilla B. Karlsson Hedestam, Mats Ohlin, Andrew M. Collins, Corey T. Watson, Christian E. Busse
Publikováno v:
ImmunoInformatics. 10:100025
Autor:
Andrew M. Collins
Publikováno v:
The International Journal of Accounting. 57
Synopsis The research problem I examine whether and how presenting a return measure (e.g., return on assets) on the face of the income statement influences non-professional investors’ judgments of a company as a potential investment. Motivation Acc