Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Andrew M Burrage"'
Autor:
Charlotte Montespan, Shauna A Marvin, Sisley Austin, Andrew M Burrage, Benoit Roger, Fabienne Rayne, Muriel Faure, Edward M Campell, Carola Schneider, Rudolph Reimer, Kay Grünewald, Christopher M Wiethoff, Harald Wodrich
Publikováno v:
PLoS Pathogens, Vol 13, Iss 2, p e1006217 (2017)
Cells employ active measures to restrict infection by pathogens, even prior to responses from the innate and humoral immune defenses. In this context selective autophagy is activated upon pathogen induced membrane rupture to sequester and deliver mem
Externí odkaz:
https://doaj.org/article/0551d04c28044773b91e82f586f80a39
Autor:
David Freeman, Rudy Cedillos, Samantha Choyke, Zana Lukic, Kathleen McGuire, Shauna Marvin, Andrew M Burrage, Stacey Sudholt, Ajay Rana, Christopher O'Connor, Christopher M Wiethoff, Edward M Campbell
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62143 (2013)
α-synuclein dysregulation is a critical aspect of Parkinson's disease pathology. Recent studies have observed that α-synuclein aggregates are cytotoxic to cells in culture and that this toxicity can be spread between cells. However, the molecular m
Externí odkaz:
https://doaj.org/article/41aa07bb8d2b404984b03817f68565d6
Autor:
Aisha T. Burton, Debora Kálalová, Elizabeth V. Snider, Andrew M. Burrage, Libor Krásný, Daniel B. Kearns
Publikováno v:
bioRxiv
Sigma factors bind and direct the RNA polymerase core to specific promoter sequences and alternative sigma factors direct transcription of different regulons of genes. Here, we study the pBS32 plasmid-encoded sigma factor SigN ofBacillus subtilisto d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7097f8a247f7491812927ef3d52753e4
https://europepmc.org/articles/PMC10055396/
https://europepmc.org/articles/PMC10055396/
Publikováno v:
Journal of Bacteriology. 200
Bacterial flagella contain an axle-like rod that transits the cell envelope and connects the transmembrane basal body to the extracellular hook and filament. Although the rod is a crucial component of the flagellum, its structure and assembly are poo
Autor:
Sandra Postel, Albina Orlova, Daniel B. Kearns, Eric J. Sundberg, Reece E. Clark, Andrew M. Burrage, Edward H. Egelman, Fengbin Wang
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
The bacterial flagellar filament has long been studied to understand how a polymer composed of a single protein can switch between different supercoiled states with high cooperativity. Here we present near-atomic resolution cryo-EM structures for fla
Autor:
Richard W. Moyer, Andrew J. Smith, Amanda D. Rice, Daniele M. Swetnam, Andrew M. Burrage, Mathew M. Adams, Amy L. MacNeill, Scott F. Lindsey, Brandi R. Manning, Greg Wallace
Publikováno v:
Journal of Virology. 88:7753-7763
The process of vaccination introduced by Jenner generated immunity against smallpox and ultimately led to the eradication of the disease. Procedurally, in modern times, the virus is introduced into patients via a process called scarification, perform
Autor:
Brandi R. Manning, Andrew M. Burrage, Richard W. Moyer, Daniele M. Swetnam, Amanda D. Rice, Amy L. MacNeill, Andrew J. Smith, Stacey A. Gray, Karen L. Denzler, Scott F. Lindsey, Greg Wallace, Bertram L. Jacobs, Nobuko Fukushima
Publikováno v:
Vaccine. 29:7659-7669
Vaccinia virus deleted for the innate immune evasion gene, E3L, has been shown to be highly attenuated and yet induces a protective immune response against challenge by homologous virus in a mouse model. In this manuscript the NYCBH vaccinia virus va
Autor:
Alice Robertson, Scott F. Lindsey, Richard W. Moyer, Andrew M. Burrage, Daniele M. Swetnam, Brandi R. Manning, Randall Lanier, George R. Painter, Andrew J. Smith, Stacey A. Gray, Bernhard Lampert, Mathew M. Adams, Amanda D. Rice, Scott Foster, Greg Wallace
Publikováno v:
Viruses
Viruses, Vol 3, Iss 1, Pp 47-62 (2011)
Viruses, Vol 3, Iss 1, Pp 47-62 (2011)
CMX001, a lipophilic nucleotide analog formed by covalently linking 3-(hexdecyloxy)propan-1-ol to cidofovir (CDV), is being developed as a treatment for smallpox. In the absence of human cases of smallpox, new treatments must be tested for efficacy i
Publikováno v:
Biophysical Journal. 112:334a
The bacterial flagellar filament has been an important model system in structural biology. Current models are based upon the notion that subunits can switch between two stable states, one forming left-handed 11-start protofilaments and the other form
Publikováno v:
Methods in Molecular Biology ISBN: 9781627036009
Imaging host-pathogen interactions in real time can provide significant insight into dynamic processes and provide information about time and space of their occurences. Here, we present detailed experimental instructions on how to image the membrane