Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Andrew M, White"'
Autor:
Ilana Schlam, Sarah E. Church, Tyler D. Hether, Krysta Chaldekas, Briana M. Hudson, Andrew M. White, Emily Maisonet, Brent T. Harris, Sandra M. Swain
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background The characterization of the immune component of the tumor microenvironment (TME) of human epidermal growth factor receptor 2 positive (HER2+) breast cancer has been limited. Molecular and spatial characterization of HER2+ TME of p
Externí odkaz:
https://doaj.org/article/815f26c1bb0147c2a0736d6023a43c34
Cytotoxic Spiroepoxide Lactone and Its Putative Biosynthetic Precursor from Goniobranchus Splendidus
Autor:
Louise C. Forster, Gregory K. Pierens, Andrew M. White, Karen L. Cheney, Pradeep Dewapriya, Robert J. Capon, Mary J. Garson
Publikováno v:
ACS Omega, Vol 2, Iss 6, Pp 2672-2677 (2017)
Externí odkaz:
https://doaj.org/article/f193e61954dd474da0183f36c5846866
Autor:
Isabella R. Palombi, Nicole Lawrence, Andrew M. White, Caitlin L. Gare, David J. Craik, Brendan J. McMorran, Lara R. Malins
Publikováno v:
Bioconjugate Chemistry.
Autor:
Penelope‐Marie B. Clanor, Christine N. Buchholz, Jonathan E. Hayes, Michael A. Friedman, Andrew M. White, Ray A. Enke, Christopher E. Berndsen
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 90:1584-1593
The cone-rod homeobox (CRX) protein is a critical K50 homeodomain transcription factor responsible for the differentiation and maintenance of photoreceptor neurons in the vertebrate retina. Mutant alleles in the human gene encoding CRX result in a va
Autor:
Cedric P. van den Berg, Karen L. Cheney, Mary J. Garson, Anne E. Winters, Weili Chan, Andrew M. White
Publikováno v:
Journal of Animal Ecology. 91:831-844
Defensive chemicals are used by plants and animals to reduce the risk of predation through different mechanisms, including toxins that cause injury and harm (weapons) and unpalatable or odiferous compounds that prevent attacks (deterrents). However,
Autor:
Justin R Mascitelli, Pablo Harker, Christopher J Stapleton, Robert W. Regenhardt, David Case, Aman B. Patel, Scott B. Raymond, Matthew J. Koch, Andrew M. White, Jared B. Cooper, Adam A Dmytriw, Naif M. Alotaibi, T. Tyler Patterson, Joshua Seinfeld, Thabele M Leslie-Mazwi, Justin E Vranic, Chirag D. Gandhi, Fawaz Al-Mufti, Rajiv Gupta, Christopher Roark
Publikováno v:
The Neuroradiology Journal. 35:461-467
Purpose Flow diverting stents have revolutionized the treatment of intracranial aneurysms through endoluminal reconstruction of the parent vessel. Despite this, certain aneurysms require retreatment. The purpose of this study was to identify clinical
Autor:
Jennifer N. Pearson, Shane Rowley, Li-Ping Liang, Andrew M. White, Brian J. Day, Manisha Patel
Publikováno v:
Neurobiology of Disease, Vol 82, Iss , Pp 289-297 (2015)
Cognitive dysfunction is an important comorbidity of temporal lobe epilepsy (TLE). However, no targeted therapies are available and the mechanisms underlying cognitive impairment, specifically deficits in learning and memory associated with TLE remai
Externí odkaz:
https://doaj.org/article/8aa29d3d42d347fd8c98ce88ce74a2e9
Autor:
Marco I. González, Heidi L. Grabenstatter, Christian A. Cea-Del Rio, Yasmin Cruz Del Angel, Jessica Carlsen, Rick P. Laoprasert, Andrew M. White, Molly M. Huntsman, Amy Brooks-Kayal
Publikováno v:
Neurobiology of Disease, Vol 77, Iss , Pp 246-256 (2015)
In this study, we analyzed the impact that spontaneous seizures might have on the plasma membrane expression, composition and function of GABAA receptors (GABAARs). For this, the tissue of chronically epileptic rats was collected within 3 h of seizur
Externí odkaz:
https://doaj.org/article/c049b342e2c54635bd33858d0df35b9f
Autor:
Valentin Jakob, Ben G.E. Zoller, Julia Rinkes, Yingwen Wu, Alexander F. Kiefer, Michael Hust, Saskia Polten, Andrew M. White, Peta J. Harvey, Thomas Durek, David J. Craik, Andreas Siebert, Uli Kazmaier, Martin Empting
Small macrocyclic peptides are promising candidates for new anti-infective drugs. To date, such peptides have been poorly studied in the context of anti-virulence targets. Using phage display and a self-designed peptide library, we identified a cycli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e738afb2fdc11b9e7e791db3ccd0a1b
Autor:
Andrew M. White, Anita Dellsén, Niklas Larsson, Quentin Kaas, Frank Jansen, Alleyn T. Plowright, Laurent Knerr, Thomas Durek, David J. Craik
Publikováno v:
Journal of medicinal chemistry. 65(19)
In this work, cysteine staples were used as a late-stage functionalization strategy to diversify peptides and build conjugates targeting the melanocortin G-protein-coupled receptors [melanocortin receptor-1 (MC1R) and MC3R-MC5R]. Monocyclic and bicyc