Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Andrew Lagree"'
Autor:
Khadijeh Saednia, Andrew Lagree, Marie A. Alera, Lauren Fleshner, Audrey Shiner, Ethan Law, Brianna Law, David W. Dodington, Fang-I Lu, William T. Tran, Ali Sadeghi-Naini
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Complete pathological response (pCR) to neoadjuvant chemotherapy (NAC) is a prognostic factor for breast cancer (BC) patients and is correlated with improved survival. However, pCR rates are variable to standard NAC, depending on BC subtype.
Externí odkaz:
https://doaj.org/article/fce47cdfdcf143ec9bb40499db4f9497
Autor:
Audrey Shiner, Alex Kiss, Khadijeh Saednia, Katarzyna J. Jerzak, Sonal Gandhi, Fang-I Lu, Urban Emmenegger, Lauren Fleshner, Andrew Lagree, Marie Angeli Alera, Mateusz Bielecki, Ethan Law, Brianna Law, Dylan Kam, Jonathan Klein, Christopher J. Pinard, Alex Shenfield, Ali Sadeghi-Naini, William T. Tran
Publikováno v:
Genes, Vol 14, Iss 9, p 1768 (2023)
Up to 30% of breast cancer (BC) patients will develop distant metastases (DM), for which there is no cure. Here, statistical and machine learning (ML) models were developed to estimate the risk of site-specific DM following local-regional therapy. Th
Externí odkaz:
https://doaj.org/article/86541a385d4c44008cd2fe708c23af76
Autor:
Andrew Lagree, Audrey Shiner, Marie Angeli Alera, Lauren Fleshner, Ethan Law, Brianna Law, Fang-I Lu, David Dodington, Sonal Gandhi, Elzbieta A. Slodkowska, Alex Shenfield, Katarzyna J. Jerzak, Ali Sadeghi-Naini, William T. Tran
Publikováno v:
Current Oncology, Vol 28, Iss 6, Pp 4298-4316 (2021)
Background: Evaluating histologic grade for breast cancer diagnosis is standard and associated with prognostic outcomes. Current challenges include the time required for manual microscopic evaluation and interobserver variability. This study proposes
Externí odkaz:
https://doaj.org/article/e432955289cb4ecdacbc77ecf0a36083
Autor:
Andrew Lagree, Majidreza Mohebpour, Nicholas Meti, Khadijeh Saednia, Fang-I. Lu, Elzbieta Slodkowska, Sonal Gandhi, Eileen Rakovitch, Alex Shenfield, Ali Sadeghi-Naini, William T. Tran
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Breast cancer is currently the second most common cause of cancer-related death in women. Presently, the clinical benchmark in cancer diagnosis is tissue biopsy examination. However, the manual process of histopathological analysis is labori
Externí odkaz:
https://doaj.org/article/d7bbeb5b75be4d00a2d11586bba4830e
Autor:
Christopher J. Pinard, Andrew Lagree, Fang-I Lu, Jonathan Klein, Michelle L. Oblak, Roberto Salgado, Juan Carlos Pinto Cardenas, Barbara Brunetti, Luisa Vera Muscatello, Giuseppe Sarli, Maria Pia Foschini, Alexandros Hardas, Simon P. Castillo, Khalid AbdulJabbar, Yinyin Yuan, David A. Moore, William T. Tran
Publikováno v:
Cancers, Vol 14, Iss 20, p 5008 (2022)
Despite the important role of preclinical experiments to characterize tumor biology and molecular pathways, there are ongoing challenges to model the tumor microenvironment, specifically the dynamic interactions between tumor cells and immune infiltr
Externí odkaz:
https://doaj.org/article/d659e9b586be427b9bc90a1df3192ca7
Autor:
William T Tran, Harini Suraweera, Karina Quaioit, Daniel Cardenas, Kai X Leong, Irene Karam, Ian Poon, Deok Jang, Lakshmanan Sannachi, Mehrdad Gangeh, Sami Tabbarah, Andrew Lagree, Ali Sadeghi-Naini, Gregory J Czarnota
Publikováno v:
Future Science OA, Vol 6, Iss 1 (2020)
Aim: We aimed to identify quantitative ultrasound (QUS)-radiomic markers to predict radiotherapy response in metastatic lymph nodes of head and neck cancer. Materials & methods: Node-positive head and neck cancer patients underwent pretreatment QUS i
Externí odkaz:
https://doaj.org/article/e8818954383d4176870a39897b6c6830
Autor:
Romuald Ferre, Janne Elst, Seanthan Senthilnathan, Andrew Lagree, Sami Tabbarah, Fang-I Lu, Ali Sadeghi-Naini, William T. Tran, Belinda Curpen
Publikováno v:
Breast Disease. 42:59-66
OBJECTIVES: Early diagnosis of triple-negative (TN) and human epidermal growth factor receptor 2 positive (HER2+) breast cancer is important due to its increased risk of micrometastatic spread necessitating early treatment and for guiding targeted th
Autor:
Sonal Gandhi, Lauren Fleshner, Ali Sadeghi-Naini, Ethan Law, Katarzyna J. Jerzak, Andrew Lagree, Sami Tabbarah, Nicholas Meti, Elzbieta Slodkowska, Majid Mohebpour, William T. Tran, Alex Kiss, Fang-I Lu, Khadijeh Saednia
Publikováno v:
JCO Clinical Cancer Informatics. :66-80
PURPOSE Neoadjuvant chemotherapy (NAC) is used to treat locally advanced breast cancer (LABC) and high-risk early breast cancer (BC). Pathological complete response (pCR) has prognostic value depending on BC subtype. Rates of pCR, however, can be var
Autor:
Majid Mohebpour, Ali Sadeghi-Naini, Sami Tabbarah, Andrew Lagree, David W. Dodington, Fang-I Lu, William T. Tran
Publikováno v:
Breast Cancer Research and Treatment. 186:379-389
Neoadjuvant chemotherapy (NAC) is used to treat patients with high-risk breast cancer. The tumor response to NAC can be classified as either a pathological partial response (pPR) or pathological complete response (pCR), defined as complete eradicatio
Autor:
Eileen Rakovitch, Charmaine Childs, Ali Sadeghi-Naini, Khadijeh Saednia, Edward Chow, William T. Tran, Andrew Lagree, Eduardo Garcia, Michael Hall, Jonathan Klein, Sami Tabbarah, Tina Wu
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 106:1071-1083
Purpose\ud \ud Radiation-induced dermatitis is a common side effect of breast radiation therapy (RT). Current methods to evaluate breast skin toxicity include clinical examination, visual inspection, and patient-reported symptoms. Physiological chang